Hazardous organic pollutants in indoor dust from elementary schools and kindergartens in Greece: Implications for children's health

Besis, Athanasios; Avgenikou, Anna; Pantelaki, Ioanna; Serafeim, Eleni; Georgiadou, Eleni; Voutsa, Dimitra; Samara, Constantini

doi:10.1016/j.chemosphere.2022.136750

Cited by 18 publications

(5 citation statements)

References 86 publications

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“…Both locations were observed as the most ventilated and spacious locations among all the microenvironments. Furthermore, levels of total PAEs reported in this work were lower than those reported in other regions, such as Greece 797 μg/g 66 , China 592 μg/g 12 , Saudi Arabia 663 μg/g 10 , and USA 214 μg/g 55 . The gas/particle partitioning of PAEs is integral to their indoor fate and health risks.…”

Section: Resultscontrasting

confidence: 85%

Levels and health risk assessments of Phthalate acid esters in indoor dust of some microenvironments within Ikeja and Ota, Nigeria

Anake

Nnamani

2023

Sci Rep

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The levels, profiles of Phthalate acid esters (PAEs) and their associated health risk in children and adults using indoor dust samples were assessed from nine (9) microenvironments in Nigeria. Six PAEs congeners were determined using Gas Chromatography–Mass Spectrometry and the human health risk assessments of PAEs exposure to children and adults were computed using the United States Environmental Protection Agency (USEPA) exposure model. The mean concentrations of the total PAEs (Σ6PAEs) in indoor dust across the study locations ranged from 1.61 ± 0.12 to 53.3 ± 5.27 μg/g with 72.0% of di-n-octyl phthalate (DnOP) as the most predominant contributor of PAEs in sample locations B, C, D, E, F and G. PAEs estimated daily intake results exceeded the USEPA value of 20 and 50 kg/bw/day for children and adults respectively in some locations. Non-carcinogenic risk exposure indicated no risk (HI < 1), while the carcinogenic risk was within the recommended threshold of 1.00 × 10–4 to 1.00 × 10–6 for benzyl butyl phthalate and bis-2-ethylhexyl phthalate. From our findings, lower levels of PAEs were observed in locations with good ventilation system. Also, the human health risk evaluation indicated indoor dust ingestion as the dominant exposure route of PAEs for both children and adults, while the children were at a higher risk of PAEs exposure. To protect children susceptible to these endocrine-disrupting pollutants, soft vinyl children’s toys and teething rings should be avoided. Appropriate policies and procedures on the reduction of PAEs exposure to humans should be enacted by all stakeholders, including government regulatory agencies, industries, school administrators and the entire community.

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Section: Resultscontrasting

confidence: 85%

Levels and health risk assessments of Phthalate acid esters in indoor dust of some microenvironments within Ikeja and Ota, Nigeria

Anake

Nnamani

2023

Sci Rep

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“…Triphenyl phosphine oxide (TPPO) is a widely used synthetic intermediate in pharmaceutical products(29) and was detected here in 3% of samples ( Table 1, Figure S5 ). TPPO has begun to be widely detected in indoor air, dust and aquatic systems,(30,31) but has only rarely been detected in human samples. (24,29) Other confirmed industrial intermediates were the related isomers 1- and 2-naphthalene sulfonate ( Table 1, Figure S12 ), used in textile, pharmaceutical and agrochemical production(32,33).…”

Section: Resultsmentioning

confidence: 99%

Longitudinal Exposomics in a Multiomic Wellness Cohort Reveals Distinctive and Dynamic Environmental Chemical Mixtures in Blood

Sdougkou,

Papazian,

Bonnefille

et al. 2024

Preprint

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Chemical exposomes can now be comprehensively measured in human blood, but robust application of chemical exposomics in cohort studies requires knowledge of the longitudinal stability and interindividual variability of exogenous molecular profiles. Here we applied chemical exposomics to plasma of 46 adults, each sampled six times over two years in a multiomic wellness cohort. New chemicals were discovered, distinctive co-exposure patterns were observed, and intra-class correlation coefficients (ICC) for 519 confidently annotated substances are reported to support study design. Longitudinal stability of the chemical exposome (mean ICC 0.30) was significantly lower than the proteome, metabolome, lipidome or microbiome, and must be measured more frequently than other molecular profiles in health studies. Mixed-effects models nevertheless revealed significant associations between testosterone and perfluoroalkyl substances, and significant time-trends for low and high stability exposures alike. Complex exposome data structures were visualized and explored, demonstrating great potential for longitudinal exposomics in precision health research.

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“…These values are lower than the concentrations reported by Kim et al, (2022) (1310.00 µg/g), but in the range of those observed by Blanchard et al, (2014) in samples of settled dust. In this study, schools with higher DEHP likely re ect the presence of plastic toys in the classrooms, use of plastics in classroom material and of PVC ooring (major sources of phthalates in indoor dust) (Besis et al, 2023;Jeon et al, 2016).…”

Section: Organic Tracer Compound Concentrationsmentioning

confidence: 96%

“…Elementary school students are more vulnerable than adults to exposure to particulate matters ( ne dust) due to their earlier developmental stage. Children inhale the air 3-5 times more than adults and are exposed to a higher level of pollution per lung area (Besis et al, 2023;Sujeong et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

Determination of polycyclic aromatic hydrocarbons and organic molecular tracer compounds in dusts samples from schools in Puchuncavi and Quintero (Chile)

Parra,

Bravo,

Drooge

2024

Preprint

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This investigation was conducted in order to gain first insight into concentrations, distribution patterns and potential sources of 16 US EPA priority polycyclic aromatic hydrocarbons (PAHs) and organic molecular tracer compounds in dust samples collected in the Valparaiso region, Chile. Dust was sampled in schools (indoor and outdoor) that are ubicated in Puchuncavi (Greda, Greda los Alerces, Chocota,and Basica Horcon) and Quintero ( Liceo Politecnico, Inglès Quintero, Faro, Santa Filomena). Source apportionment analysis using the concentrations of PAHs; glucose, mannitol, sucrose, fructose; di-2-ethylhexyl phthalate; hopanes, and levoglucosan as molecular tracer compounds showed four sources of contribution; the first related to combustion, a source represented to traffic, a third source dominated for soil + plastic, and a source of biomass burning. Outdoor traffic emissions and combustion were the main pollution sources in the outdoor as well as indoor ambient air of the schools, while soil + plastic were an important indoor source.

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Hazardous organic pollutants in indoor dust from elementary schools and kindergartens in Greece: Implications for children's health

Cited by 18 publications

References 86 publications

Levels and health risk assessments of Phthalate acid esters in indoor dust of some microenvironments within Ikeja and Ota, Nigeria

Levels and health risk assessments of Phthalate acid esters in indoor dust of some microenvironments within Ikeja and Ota, Nigeria

Longitudinal Exposomics in a Multiomic Wellness Cohort Reveals Distinctive and Dynamic Environmental Chemical Mixtures in Blood

Determination of polycyclic aromatic hydrocarbons and organic molecular tracer compounds in dusts samples from schools in Puchuncavi and Quintero (Chile)

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