Hazardous Private Healthcare Waste Management and Forecast of Medical Waste Generation

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Anti-inflammatory-analgesic medication is known to have a wide spread, its indications going beyond the area of rheumatology, aimed at various fields, cardiology, nephrology, hematology,neurology, etc. Many years of aspirin has constituted the health expectation of millions of patients. Most nonsteroidal anti-inflammatory analgesics (ASNS) are acidic compounds derived mainly from carboxylic acids and enolic acids. The non-acidic compounds are numerically reduced and relatively unrelated. The main effects of non-steroidal anti-inflammatory analgesics arise following antipyretic action, analgesic action and anti-immflamatory in varying proportions to each structural group. Each drug has the specificity of single actions, the global way of explaining the clinical effects remains little known. Anti-inflammatory (anti-termic) in acute rheumatism or other inflammatory joint disorders, anti-platelet antiaggregant, aspirin prevents aggregation of blood platelets (which have a role in stopping bleeding).This is why it is used to prevent thrombosis (clotting of blood in the arteries or veins) with an impOliant role in preventing myocardial infarction. The study includes 126 patients who often used aspirin. Interaction of aspirin with other drugs mainly occurs in the plasma albumin, platelets, liver, kidney and gastrointestinal tract. Considered a common drug, often used by patients without the physician�s indication, some of them under maintenance medication (corticosteroid, anticoagulants, antiplatelet, antidiabetics, cytostatics), aspirin may cause important complications.

Section: Resultsmentioning

confidence: 99%

General and Particular Structural Characteristics of Acetylsalicylic Acid - Aspirine Chemical properties

Topor¹,

Nechita²,

Debita³

et al. 2019

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“…Numerous studies demonstrating the efficacy and versatility of that matrix-forming agent are provided in the literature [8]. Similar studies were carried out in the literature [9][10][11][12][13][14][15][16][17][18][19][20][21].…”

mentioning

confidence: 99%

Study on the Formulation and Pharmacotechnical Characterization of Hydrophilic Matrix Tables with Amiodarone Chlorhydrate

Crețeanu¹,

Ştefanache²,

Vieriu³

et al. 2019

The study is based on new oral matrix tablets based on Kollidon®SR and chitosan, formulated in order to optimize the low oral bioavailability of amiodarone, a class III antiarrhythmic drug. Pharmacotechnical characterization included the analysis of flowability and compressibility properties (flow time, friction coefficient, angle of repose, Hausner ratio, Carr Index), and of pharmaco-chemical characteristics (mass and dose uniformity, thickness, diameter, mechanical strength, friability, degree of softening, in vitro release profile) of the tablets obtained using direct compression method. The results obtained have shown that both Kollidon®SR and chitosan may be used as matrix forming agents when combined with amiodarone. In vitro dissolution tests revealed that the nine formulations studied provided a prolonged release of amiodarone when compared to an industrial pharmaceutical product formulated as conventional release tablets.

“…Learning difficulties are common in people with this condition, especially among children with epilepsy. The stigma of epilepsy can also affect the families of the patients [19][20][21][22][23][24][25][26]. People with epilepsy may experience certain disorders, depending partially on the current epileptic syndrome, including depression, anxiety, and migraines.…”

mentioning

confidence: 99%

The Role of Chemical Factors in the Occurrence of the Nervous System Disorders Posttraumatic epilepsy

Raftu¹,

Debita²,

Dinu³

et al. 2019

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Because an epilepsy occurring at a time interval after a cranio-cerebral trauma can be considered post-traumatic epilepsy, so in a causal relationship with the trauma, it must meet some conditions. Epilepsy is a chronic cerebral disorder manifested by recurrent, spontaneous epileptic seizures; with a sudden episode, a stereotype of motor, sensitive, sensory, behavioural manifestation, and / or alteration of the state of consciousness due to sudden, unprovoked activation of a neuronal population. To support the diagnosis of the first epileptic seizure, additional information is required from the anamnesis, the general and neurological clinical examination of the patient. The diagnostic approach continues, under the direct supervision of the neurologist, by identifying the aetiology of epilepsy. The study includes 27 epilepsy cases studied in 2014-2018. The most common type of epileptic seizure is the tonic-clonic one that affects the entire brain, and this is also the most visible form of epilepsy that manifests itself in the form of a generalized crisis, identified by involuntary convulsions that lead to partial or total loss of consciousness during the crisis. Epilepsy is caused by an explosion of intense electrical activity that suddenly occurs in the brain, and the resulting convulsions can occur in several forms depending on the area where this intense brain activity occurs.