Hazards of challenge tests in atopic dermatitis

David, T J

doi:10.1111/j.1398-9995.1989.tb02464.x

Cited by 28 publications

(3 citation statements)

References 39 publications

(53 reference statements)

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“…Altbough there are several pitfalls when conducting blinded food challenges (7,8) no procedure can exclude the need for proper double-blind, placebo-controlled food challenge (DBPCFC). DBPCFC may be performed in various ways, e.g.…”

mentioning

confidence: 99%

Other IgE‐ and Non‐IgE‐Mediated Reactions of the Skin

Bindslev‐Jensen

Østerballe

2008

Food Allergy

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Respiratory reactions induced by food challenges in adultsBindslev-Jensen C. Respiratory reactions itiduced by food challenges in adults. Pedialr Allergy Immunol 1992: 3: 2UI-205.Respiratory symptoms (asthma and/or rhinoconjunctivitis) upon oral intake of foods is most frequently seen in children, although sensitization in adulthood occurs. The diagnosis of food allergy must ecxlusive be based on the outcome of Double-Blind, Placebo-Controlled Food Challenges (DBPCFC) false positive results in the challenge tests and resulting unnecessary diet therapy. Only a proportion of true food allergic patients also develop respiratory symptoms, the most predominant symptoms being skin-and gastrointestinal sympoms upon intake. A striking feature in DBPCFC' positive patients, is the concomitant development of symptoms and signs from more than one organ system {respiratory, skin and/or gastrointestinal). Treatment of food induced respiratory symptoms should be strict avoidance, since no pharmacologic agents has convincingly been shown to protect against development of asthma.

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confidence: 99%

Other IgE‐ and Non‐IgE‐Mediated Reactions of the Skin

Bindslev‐Jensen

Østerballe

2008

Food Allergy

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“…It appears that asthmatics are at increased risk for severe or fatal anaphylaxis,20 and adrenal atrophy and adrenal-pituitary axis suppression is one possible explanation. (8) Observation for several hours -There is a risk of relapse when the effect of antianaphylactic drugs has begun to wear off, or where there is continued absorption of the trigger food from the gastrointestinal tract.…”

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confidence: 99%

“…(8) Where the life threatening reaction comprises severe bronchoconstriction, then adrenaline is less effective3l and more toxic than the use of selective ,2-agonists (for example, nebulised salbutamol or terbutaline). (9) Supply of preloaded syringes with adrenaline has been associated with exclusion from school in some cases.…”

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confidence: 99%

Management of anaphylactic reactions to food.

Patel¹,

Radivan²,

David³

1994

Archives of Disease in Childhood

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A 12 year old boy with eczema, asthma, and severe intolerance to cows' milk protein ate a small amount of food which contained casein. He developed a severe anaphylactic reaction, and within minutes he was dead.' After recent publicity of similar cases in the press, this is a scenario now greatly feared by parents of children with food intolerance. This article addresses two controversial issues, the immediate treatment of anaphylactic reactions, and the role of adrenaline for home use. The terms anaphylaxis or anaphylactic shock are used in this context to mean a severe reaction of rapid onset, with circulatory collapse and hypotension. Some have used the term anaphylaxis to describe any immediate allergic reaction mediated by IgE antibodies, however mild, but such usage fails to distinguish between a trivial event (for example, a skin test reaction) and a life threatening one. Others use the terms local anaphylaxis and systemic anaphylaxis to describe respectively local reactions (for example, acute angioedema) and generalised reactions; we confine the term anaphylaxis to the latter.

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Anaphylaxis

Pediatric Allergy, Asthma and Immunology

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Hazards of challenge tests in atopic dermatitis

Cited by 28 publications

References 39 publications

Other IgE‐ and Non‐IgE‐Mediated Reactions of the Skin

Other IgE‐ and Non‐IgE‐Mediated Reactions of the Skin

Management of anaphylactic reactions to food.

Anaphylaxis

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