Hazards of Improper Dispensary: Literature Review and Report of an Accidental Chloroform Injection

Verma, Prashant; Tordik, Patricia A.; Nosrat, Ali

doi:10.1016/j.joen.2018.02.024

Cited by 15 publications

(7 citation statements)

References 34 publications

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“…Even though not all the samples were completely free from remnants, due to the time-dependent dissolution effect [ 22 , 23 ], it can be expected that the longer the period of agitation, the better the cleanliness achieved in complex root canal anatomies. Due to the low cytotoxicity profile of the suggested solvents in the mixture, as compared to the traditional chloroform, damage to the dentine or other relevant cytotoxic hazards are not expected, even with longer periods [ 43 , 44 , 45 ]. Nevertheless, all procedures must follow the gold standard quality guidelines for endodontic treatment [ 46 ].…”

Section: Discussionmentioning

confidence: 99%

Effect of Sonic Agitation of a Binary Mixture of Solvents on Filling Remnants Removal as an Alternative to Apical Enlargement—A Micro-CT Study

Ferreira

Babo

Braga

et al. 2020

JCM

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Background: This work aimed to evaluate the efficacy of sonic agitation of a binary mixture of solvents (methyl ethyl ketone/tetrachloroethylene) on filling remnants removal and compare the effects of solvent agitation with the enlargement to the next instrument size. Methods: Twenty-four mandibular incisors were prepared with ProTaper Next (X1, X2) and obturated with the single-cone technique and AH Plus sealer. The teeth were retreated with ProTaper Universal Retreatment and ProTaper Next and divided into two groups (n = 12) according to the final instrument (X3 or X4). All canals were submitted to a supplementary procedure consisting of a mixture of solvents―methyl ethyl ketone/tetrachloroethylene, agitated with EndoActivator. The volume of filling remnants was assessed through micro-computed tomography in the apical 5 mm. Statistical analysis was performed with a significance level of 5%. Results: The supplementary procedure of agitation of the solvent mixture was beneficial in both groups (p < 0.05). There were no statistically significant differences between canals re-prepared until X4 and canals re-prepared until X3 plus solvent (p > 0.05). Conclusions: An additional step with a two-solvent solution potentiated by EndoActivator showed to be very effective for the removal of gutta-percha and resinous sealer remnants from apical root canals of mandibular incisors, avoiding further enlargement.

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Section: Discussionmentioning

confidence: 99%

Effect of Sonic Agitation of a Binary Mixture of Solvents on Filling Remnants Removal as an Alternative to Apical Enlargement—A Micro-CT Study

Ferreira

Babo

Braga

et al. 2020

JCM

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“…The exposure of humans to chloroform severely affects the central nervous system, kidneys, liver, etc. Long-term exposure may result in vomiting, nausea, dizziness, convulsions, depression, respiratory failure, coma, and even sudden death [6,7]. It is important to efficiently detect the release of chloroform because of its serious health hazards.…”

Section: Introductionmentioning

confidence: 99%

ZnO Nanocrystal-Based Chloroform Detection: Density Functional Theory (DFT) Study

et al. 2019

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We investigated the detection of chloroform (CHCl3) using ZnO nanoclusters via density functional theory calculations. The effects of various concentrations of CHCl3, as well as the deposition of O atoms, on the adsorption over ZnO nanoclusters were analyzed via geometric optimizations. The calculated difference between the highest occupied molecular orbital and the lowest unoccupied molecular orbital for ZnO was 4.02 eV. The most stable adsorption characteristics were investigated with respect to the adsorption energy, frontier orbitals, elemental positions, and charge transfer. The results revealed that ZnO nanoclusters with a specific geometry and composition are promising candidates for chloroform-sensing applications.

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“…Verma et al reported a case in which chloroform was injected accidentally instead of local anesthesia because chloroform was loaded into the anesthetic syringe. 6 But in the present case the dentist had used chloroform in an attempt to reach additional pulpal anesthesia.…”

Section: Discussionmentioning

confidence: 80%

“…We found three articles about chloroform iatrogenic burns related to dentistry, although their presentations, management and outcomes were different from the present case. 4 - 6 This paper presents a case of an ulcer in palatal and buccal mucosa due to chloroform injection in to the root canal in endodontic treatment and discusses its conservative treatment and effects on the patient’s quality of life.…”

Section: Introductionmentioning

confidence: 99%

Management of iatrogenic chloroform mucosal burn in the palate: a case report

Zonouz

Katebi

Ghavimi

et al. 2022

J Adv Periodontol Implant Dent

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Chloroform is used widely in endodontic treatments for solving gutta-percha points, but it can have-destructive effects if it comes in to contact with oral mucosa. This article presents a case of necrotic-ulcer of palatal and buccal mucosa due to injudicious use of chloroform in endodontic treatment, which-has caused severe destruction in maxilla. A conservative treatment method of repeated curettage and irrigation was used and although the lesion healed completely, it had major effects on the patient’s quality of life including loss of two teeth. It is important that dentist be aware of the devastating effects of imprudent application of various chemicals used in dentistry. The conservative treatment used for this case can be helpful option for similar cases.

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Hazards of Improper Dispensary: Literature Review and Report of an Accidental Chloroform Injection

Cited by 15 publications

References 34 publications

Effect of Sonic Agitation of a Binary Mixture of Solvents on Filling Remnants Removal as an Alternative to Apical Enlargement—A Micro-CT Study

Effect of Sonic Agitation of a Binary Mixture of Solvents on Filling Remnants Removal as an Alternative to Apical Enlargement—A Micro-CT Study

ZnO Nanocrystal-Based Chloroform Detection: Density Functional Theory (DFT) Study

Management of iatrogenic chloroform mucosal burn in the palate: a case report

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