Hazards of postoperative atrial arrhythmias

Creswell, Lawrence L.; Schuessler, Richard B.; Rosenbloom, Michael; Cox, James L.

doi:10.1016/0003-4975(93)90894-n

Cited by 883 publications

(480 citation statements)

References 39 publications

Supporting

Mentioning

419

Contrasting

Unclassified

Order By: Relevance

“…Atrial fibrillation (AF) is a common complication after coronary artery bypass graft (CABG) surgery [1, 2]. AF may lead to compromised cardiac function, thromboembolism, stroke, and prolonged hospitalization [3, 4].…”

Section: Introductionmentioning

confidence: 99%

Histologic Assessment of Right Atrial Appendage Myocardium in Patients with Atrial Fibrillation after Coronary Artery Bypass Graft Surgery

Nakai

Chandy²,

Nakai

et al. 2006

Cardiology

View full text Add to dashboard Cite

Atrial fibrillation (AF) is a common complication after coronary artery bypass graft (CABG) surgery. Despite the prevalence of AF occurring after cardiac surgery, its pathophysiology is incompletely understood. Our previous study demonstrated that age and left atrial enlargement were independent predictors of postoperative AF. Accordingly, the purpose of this study was to determine whether cellular changes such as fibrosis and/or hypertrophy occurred in the atrium in patients who subsequently developed postoperative AF. Right atrial appendage tissue was obtained during atriotomy in patients undergoing elective CABG surgery. Quantitative assessment of atrial fibrosis was performed with Sirius red stain, and atrial cell diameter was measured with the HE stain. Linear regression, t test, χ² test or Fisher exact test were used for statistical analysis. Sixty-one patients (mean age 71 ± 8 years) were studied. Increasing age was significantly associated with fibrosis (beta 0.3, 95% CI: 0.06–0.55, p = 0.017). The amount of right atrial fibrosis tended to correlate with the incidence of postoperative AF (p = 0.08). Cell diameter was not significantly different between patients with versus without postoperative AF (p = 0.85). These results suggest that the age-related atrial fibrosis rather than cellular hypertrophy may be important in the pathogenesis of AF after CABG surgery and should be further investigated.

show abstract

Section: Introductionmentioning

confidence: 99%

Histologic Assessment of Right Atrial Appendage Myocardium in Patients with Atrial Fibrillation after Coronary Artery Bypass Graft Surgery

Nakai

Chandy²,

Nakai

et al. 2006

Cardiology

View full text Add to dashboard Cite

show abstract

“…AF incidence has been reported between 20% to 40% in wide series [2] [3]. Previous studies exhibited that AF frequency did not change in patients underwent beating heart technique [20]- [22].…”

Section: Discussionmentioning

confidence: 98%

“…AF can be cause postoperative morbidity and mortality especially in older patients. The incidence of postoperative AF in CABG patients has been reported as 20% -40% of patients [2] [3]. The patient's pre-existing arrhythmia [4], advanced age [4], preoperative beta-blocker medication [5], hypertension, left ventricle dysfunction, angina pectoris, MI, right coronary artery stenosis [5] AF: Atrial Fibrillation, NT-proBNP: N-terminal natriuretic peptide, T1: pre-operation time, T2:1st day after the operation, T3: 3rd day after the operation, T4: 5th day after the operation (T4).…”

Section: Discussionmentioning

confidence: 99%

“…Especially in older patients AF as a postoperative complication can occur because of postoperative morbidity and mortality. The incidence of postoperative AF after CABG has been reported as 20% -40% of patients [2] [3]. The patient's pre-existing arrhythmia [4], advanced age [4], preoperative beta-blocker medication [5], hypertension, left ventricule dysfunction, angina pectoris, myocard infarction (MI), and right coronary artery stenosis [5] [6] are accepted the important factors for postoperative AF risk.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The Relationship between the Changes of Blood NT-proBNP Levels and Postoperative Atrial Fibrillation Occurance in Coronary Artery By-Pass Grafting Surgery Patients

Azboy¹,

Simsek²,

Erdolu³

et al. 2016

OALib

View full text Add to dashboard Cite

Background: The new onset of atrial fibrillation (NOAF) can be occurred after coronary artery bypass grafting (CABG) surgery. NOAF can be occurred because of postoperative severe hemodynamic instability, long duration of ICU and hospital staying time, morbidity and mortality. Our aim of this study was to investigate whether N-terminal pro-brain natriuretic peptide (NT-proBNP) is a cause of NOAF after CABG. Methods: Forty CABG patients were enrolled for this study. Twenty patients operated on cardiopulmonary bypass (Group I; n: 20). The remaining patients have operated using a beating heart technique (Group II; n: 20). The NT-proBNP levels were calculated preand postoperatively. Results: High rate of NOAF was detected in group I patients (P < 0.05). In both groups, the NT-proBNP levels were low with sinus rhythm. The NT-proBNP blood levels in different times (T1, T2, T3, T4) among Group I were found higher than Group II. Conclusions: Our research demonstrated that there was a strongly close relationship between blood NT-proBNP levels' and atrial fibrillation occurrence in CABG patients. According to our results to detect postoperative AF development in early time and its treatment, blood NT-proBNP levels can be calculated in those patients for reducing morbidity and mortality due to AF.

show abstract

“…AKK, distal anastomoz sayısı AF gelişimini etkileyebildiğinden kardiyak koruma önem kazanmaktadır [13,14] . Ancak AKK ve KPB zamanı ile aritmi insidansı arasın-da çelişkili bildirimler de bulunmaktadır.…”

Section: Patofizyolojiunclassified