“…ME: Until now, the correlation between high frequency in dialysis patients and high prevalence among the general population is the most plausible explanation. However, it is not known why such large geographical variations in the general population are observed, although some authors have pointed to an association with genetic characteristics and differences in socio-economic situations (9,11). Looking at other factors, the prevalence seems to increase with the number of blood transfusions, the duration of dialysis and the mode of treatment (higher among HD than among PD patients) (12).…”