2024
DOI: 10.15789/2220-7619-hdr-16597
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HCV drug resistance mutations in HIV-infected patients

D. E. Reingardt,
Yu. V. Ostankova,
E. V. Anufrieva
et al.

Abstract: Aim. The aim of our work was to assess the mutations prevalence in the HCV drug resistance in the NS3, NS5A, NS5B genes in HIVinfected patients. Materials and methods. The material of the study was 157 blood plasma samples from HIV patients living in the Leningrad Region, with virological inefficiency of antiretroviral therapy. Samples were examined for the presence of anti-HCV antibodies and HCV RNA. In the case of detecting HCV RNA, amplification was carried out using a set of primers co-flanking the N… Show more

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