HDN in a mother undergoing in vitro fertilization with donor ova

ABO hemolytic disease of the fetus and newborn: an iatrogenic complication of heterologous assisted reproductive technology‐induced pregnancy

“…Cases of other pathologies in newborns resulting from complications from ART are rare. These clinical cases permit a focused look at possible complications in newborns resulting from blood type incompatibilities (e.g., ABO and Rh) and using heterologous maternal and/or paternal type ART 17,18 …”

“…These clinical cases permit a focused look at possible complications in newborns resulting from blood type incompatibilities (e.g., ABO and Rh) and using heterologous maternal and/or paternal type ART. 17,18 We believe that knowing donor blood type is invaluable in preventing complications with ART. Furthermore, this case suggests ethical problems, raising concerns not uncommon to pregnancies induced by ART.…”

Homozygous expression of fetal red cell antigen in donor oocyte pregnancy complicated by allo‐immunisation: are current antibody thresholds to trigger increased monitoring relevant?

“…Unexpectedly severe haemolytic disease has previously been reported in cases of donor oocyte pregnancy (Mitchell & James, 1999;Mair & Scofield, 2003), with homozygous expression of the causal red cell antigen being a possible contributory factor in some reported cases (Mair & Scofield, 2003;Patel et al, 2003). Notably, Mair and Scofield reported a case of HDFN requiring transfusion due to an anti-c which had a maximum titre of 4.…”

A novel homozygous splice‐site mutation of JK gene leads to Jk(a‐b‐) phenotype

“…1,2 The coding gene of the glycoprotein is located on chromosome 18q12.3 and is encoded by the SLC14A1 (HUT11/UT-B/JK) gene. 3 The gene contains 10 exons, with exons 3-10 (previously numbered exons [4][5][6][7][8][9][10][11] encoding mature proteins. The Kidd antigen is a part of the transmembrane glycoprotein, which is a urea transporter of red blood cells and renal vascular endothelial cells.…”