Head and neck cutaneous melanoma: A retrospective observational study on 146 patients

Koskivuo, Ilkka; Kinnunen, Ilpo; Suominen, Erkki; Talve, Lauri; Vihinen, Pia; Grénman, Reidar

doi:10.1080/02841860802404356

Cited by 15 publications

(12 citation statements)

References 27 publications

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“…We analyzed the 168 patients with primary CMHN who received treatment consistent with the NCCN guidelines . Our single‐institution study population is the largest cohort of patients with clinical stage 1 and 2 CMHN that includes data on initial treatment, recurrence, treatment of recurrence, and survival after recurrence …”

Section: Discussionmentioning

confidence: 99%

“…2 Our single-institution study population is the largest cohort of patients with clinical stage 1 and 2 CMHN that includes data on initial treatment, recurrence, treatment of recurrence, and survival after recurrence. 3,[6][7][8][9] Primary CMHN has distinctive characteristics not often found in its trunk and extremity counterparts. The unpredictable lymphatic flow, unique to the head and neck region, Values are presented as n (%) unless noted otherwise.…”

Section: Discussionmentioning

confidence: 99%

“…10 Koskivuo et al supports that the scalp subsite imparts worse prognosis, but when the head and neck region as a whole is compared to other regions of the body no survival difference is observed. 6 The Multicenter Selective Lymphadenectomy Trial (MSLT), which included mostly patients with intermediate thickness melanoma, found the 10-year melanoma-specific survival to be 81% in those patients who underwent SLNB, and 78% in those patients who were observed for regional metastases. 11 The MSLT also supports that discovering clinically occult metastases in the SLNB is a strong predictor of recurrence and death.…”

Section: Discussionmentioning

confidence: 99%

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Patterns of recurrence and retreatment outcomes among clinical stage I and II head and neck melanoma patients

et al. 2019

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Background The objective of this study was to determine survival outcomes in patients who underwent retreatment of recurrent cases of cutaneous melanoma of the head and neck (CMHN). Methods Retrospective review of all patients who were treated for primary clinical stage I or II CMHN between January 1, 2000 and December 31, 2015. Results Twenty percent (33/168) of the patients developed a recurrence. Sixty‐six percent (4/6) of patients who developed local recurrence first and 50% (3/6) of patients who developed regional recurrence first were alive without evidence (NED) of disease at last follow‐up, while 0% (0/21) of patients who developed distant or simultaneous recurrences first were NED at last follow‐up. Among the 7 patients who were NED, the mean time from recurrence to last follow‐up was 735 days. Conclusions Of patients with isolated local or regional recurrences, 58% (7/12) obtained durable curative treatment for recurrent melanoma.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Patterns of recurrence and retreatment outcomes among clinical stage I and II head and neck melanoma patients

et al. 2019

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“…reported an accuracy of 99.7% in a series of 353 SNBs in head and neck melanoma cases . Their results were compared with 19 studies of SNB in head and neck melanoma between 1997 and 2010, including pooled data examining 116 failed SNBs in 1857 patients . The overall SN identification rate was 94.7%, indicating that SNB in head and neck melanoma is an accurate procedure.…”

Section: Sentinel Lymph Node Biopsy In Head and Neck Melanomamentioning

confidence: 97%

Review of the role of sentinel node biopsy in cutaneous head and neck melanoma

Roy

Whitfield

Gill

2015

ANZ Journal of Surgery

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Sentinel node biopsy (SNB) is recommended for selected melanoma patients in many parts of the world. This review examines the evidence surrounding the accuracy and prognostic value of SNB and completion neck dissection in head and neck melanoma. Sentinel nodes were identified in an average of 94.7% of head and neck cases compared with 95.3-100% in all melanoma cases. More false-negative sentinel nodes were found in head and neck cases. A positive sentinel node was associated with both lower disease-free survival (53.4 versus 83.2%) and overall survival (40 versus 84%). We conclude that SNB should be offered to all patients with intermediate and high-risk melanomas in the head and neck area. To date, evidence does not exist to demonstrate the safety of avoiding completion lymph node dissection in sentinel node-positive patients with head and neck melanoma.

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“…The basic concept of SN biopsies dictates that when these nodes are free of tumor deposits, the need for elective treatment of the neck is limited. 2,3 Although technically feasible, the procedure of SN mapping and biopsy in the head and neck area is met with several specific challenges. The lymphatic drainage is highly unpredictable, and in many cases SNs are located close to the primary lesion.…”

mentioning

confidence: 99%

Detecting Near-the-Injection-Site Sentinel Nodes in Head and Neck Melanomas With a High-Resolution Portable Gamma Camera

Hellingman

Veen

Klop

et al. 2015

Clinical Nuclear Medicine

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Head and neck cutaneous melanoma: A retrospective observational study on 146 patients

Cited by 15 publications

References 27 publications

Patterns of recurrence and retreatment outcomes among clinical stage I and II head and neck melanoma patients

Patterns of recurrence and retreatment outcomes among clinical stage I and II head and neck melanoma patients

Review of the role of sentinel node biopsy in cutaneous head and neck melanoma

Detecting Near-the-Injection-Site Sentinel Nodes in Head and Neck Melanomas With a High-Resolution Portable Gamma Camera

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