Head and neck non-Hodgkin's lymphoma: a 20-year demographic study of 381 cases

Etemad‐Moghadam, Shahroo; Tirgary, Farrokh; Keshavarz, Samaneh; Alaeddini, Mojgan

doi:10.1016/j.ijom.2010.03.029

Cited by 66 publications

(64 citation statements)

References 23 publications

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“…The commonest histological subtype of NHL was reported as diffuse mixed variant (Chakrabarti et al, 2010). In a 20-year retrospective demographic study of 381 NHL cases from Iran; the mean age of NHL was found to be 39.3 years (Etemad-Moghadam et al, 2010). In a large series of 1785 cases from Pakistan, researchers found NHL in only 27 cases; which were more common in the males; and more prevalent in the second and third decades of their lives.…”

Section: Discussionmentioning

confidence: 98%

“…From the Asian continent, large bulk of lymph node pathology articles are from Indo-Pak Subcontinent; just to mention a couple of most recent works from India (Roy et al, 2013;Reddy et al, 2014) and similarly from Pakistan (Fatima et al, 2011;Naseem et al, 2011). From the neighbouring countries of Kingdom of Saudi Arabia (KSA), there are two recent studies, one from Turkey (Tatar et al, 2011) and one from Iran (Etemad-Moghadam et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

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Pattern of Lymph Node Pathology in Western Saudi Arabia

Albasri

El-Siddig²,

Hussainy³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Background: This study aimed to characterize the histopathological pattern of lymph node pathology among Saudi patients and to highlight the age and gender variations of these lesions as base line data. Materials and Methods: We retrospectively analyzed the data from lymph node biopsy specimens received at the Department of Pathology, King Fahad Hospital, Madinah, Saudi Arabia from January 2006 to December 2013. Results: Of the 289 lymph node biopsy specimens received, 154 (53.3%) were from males and 135 (46.7%) from females giving a male: female ratio of 1.14:1. Age of the patients ranged from 2.5 to 96 years with a mean age 33.9 years. The commonest lymph node group affected was the cervical (30.4%) followed by axillary (9.7%) and inguinal (8.7%). Malignant lymphoma [71 Hodgkin's disease (HD), 57 non Hodgkin's lymphoma (NHL)] 128 (44.3%), reactive hyperplasia 68 (23.5%), and tuberculosis 41 (14.2%) were the common causes of lymph node enlargement. While HD, reactive hyperplasia and tuberculosis were commonest in young adult patients (10-29 years old) and rare above the age of 50 years; NHL was the predominant cause of lymph node enlargement above 50 years. Conclusions: Lymph node biopsy plays an important role in establishing the cause of lymphadenopathy. Among the biopsied nodes, lymphomas were the most common (44.3%) followed by non-specific reactive hyperplasia (23.5%) and tuberculous lymphadenitis (14.2%).

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Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Pattern of Lymph Node Pathology in Western Saudi Arabia

Albasri

El-Siddig²,

Hussainy³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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“…Eisnbound et al (1983; in their study of 31 case of oral NHL found 14 patients with bone involvement, only 5 of them were in the mandible. However, Pazoki et al (2003) reported 3 mandibular and 1 maxillary intrabony NHLs, and Etemad-Moghadam et al (2010) found that the mandibular lesion exceed the maxillary. In this study 38.1% of the tumors were intra-bony however the mandible was more affected than the maxilla and other oral cavity sites.…”

Section: Discussionmentioning

confidence: 99%

Oral Extranodal Non Hodgkin's Lymphoma: Series of Forty Two Cases in Malaysia

Ramanathan¹,

Mahmoud²,

Hui³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Background: Lymphoma is a malignant neoplasm of lymphoid tissue classified into Hodgkin's and nonHodgkin's types. It mostly affects lymph nodes although a considerable proportion of Non-Hodgkin's cases occur in extranodal sites. Materials and Methods: Selected cases diagnosed as non-Hodgkin's lymphoma (NHL) during the period of 1980 to 2012 were retrieved from the archives of the Oral Pathology Diagnostic Laboratory, Faculty of Dentistry, University of Malaya. The sections from the formalin-fixed paraffin embedded tissue blocks were stained with H&E as well as with LCA, CD20, and CD3. Results: The mean age was 41.6 years with a male: female ratio of 1.3:1. Out of the forty two cases, nineteen were Malays, eighteen were Chinese, followed by Indians (3) and Indonesians (2). The most common site of involvement was the mandible (22.2%), followed by the maxilla and palate (19.4% each). Most of the lesions presented as a painless progressive swelling. Only thirty six cases were further subdivided into B or T cell types. The majority were B-cell type (26 cases), of these 6 cases were Burkitt's lymphomas. Only ten cases were T-cell lymphoma, with three cases of NK/T-cell lymphoma. Conclusions: In this series of 42 patients diagnosed as extranodal non-Hodgkin's lymphoma, the lesions appeared as painless swellings, mostly in men with the mandible as the most frequent site of involvement. Majority were B-cell lymphomas with Malays and Chinese being equally affected whereas lymphomas were rare in the Indian ethnicity. T-cell lymphomas were found to be common in the Chinese ethnic group.

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“…The SG is the anatomic site of 6-26 % of extranodal NHL in the head and neck (H&N), with Taiwan having the lowest incidence, and Iran reporting the highest incidence [20,[23][24][25][26]. Within the limited literature, there is some variability in the reported histological distribution of primary SG lymphomas (Table 3), but on the whole, low grade B-cell lymphomas predominate [10-13, 27, 28].…”

Section: Discussionmentioning

confidence: 99%

Salivary Gland Lymphoproliferative Disorders: A Canadian Tertiary Center Experience

Paliga

Farmer

Bence‐Bruckler

et al. 2013

Head and Neck Pathol

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Salivary gland lymphoproliferative disorders (SGLD) are very rare tumors and clinicopathological data is sparse. In a Canadian series of 30 cases, extracted from the surgical pathology files of The Ottawa Hospital between 1990 and 2010, a clinical, histopathological, and immunophenotypic analysis was conducted. Tumors were staged using the Ann Arbor staging and classified using the World Health Organization 2008 classification. There were 15 salivary gland (SG) primary lymphomas with localized disease, predominantly mucosa associated lymphoid tissue type marginal zone lymphoma (MALT-L), but with a significant incidence of low grade follicular lymphoma (FL) and diffuse large B cell phenotype as well. There were 7 systemic SG lymphomas and 5 patients were diagnosed with lymphoproliferative disorders originating from intraparotid lymph nodes. Finally, the remaining 3 cases represented reactive sialadenitis. A literature review was conducted and our primary lymphoma group was compared to those from other countries. SGLDs are predominantly B cell lymphomas that develop in older adults. Primary tumors, which have MALT-L and low grade FL characteristics, have a favorable survival, however MALT-L have a high rate of relapse. A minority of SG lesions are excised secondary to lymphomas that definitely arose from intraparotid lymph nodes.

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Head and neck non-Hodgkin's lymphoma: a 20-year demographic study of 381 cases

Cited by 66 publications

References 23 publications

Pattern of Lymph Node Pathology in Western Saudi Arabia

Pattern of Lymph Node Pathology in Western Saudi Arabia

Oral Extranodal Non Hodgkin's Lymphoma: Series of Forty Two Cases in Malaysia

Salivary Gland Lymphoproliferative Disorders: A Canadian Tertiary Center Experience

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