Healing of self‐inflicted thermal injury of palatal mucosa by low‐level laser therapy

Abstract

Self-inflicted injury to oral mucosa is a rare entity. These injuries can be premeditated, accidental, or can result from an abnormal habit. These uncommon gingival injuries can sometimes test the clinician's diagnostic abilities as well as treatment planning skills. In conventional treatment, removal of etiology and application of topical drugs is usually sufficient for healing. However, some cases require alternative or adjunctive wound healing methods. Low-level laser therapy (LLLT) has been reported to be effective in pain management and improvement in wound healing through promotion, fortification, and commissioning of cellular cycle to generate productive and substitute cells. This report presents a case of 25-year-old female with complaints of a painful, nonhealing wound on the palate for last 6 months. She had an unusual habit of keeping burning matchsticks in her mouth. Although she had quit the habit 2 months ago after psychiatric counseling, the wound on her palate did not show any improvement in symptoms. Based on the history and clinical findings, diagnosis of chronic wound by self-inflicted thermal injury was made. LLLT was administered on the wound every 48 hours for next 10 days. The burn wound healed completely after five applications of LLLT.

The Combination of Antimicrobial Photodynamic Therapy and Photobiomodulation Therapy for the Treatment of Palatal Ulcers: A Case Report

“…When compared with antibiotic therapy used alone, 10 the present clinical results demonstrated a substantial relief from the painful sensation in a short period of time, achieving healthy tissue marked by the absence of bleeding in few days and more organized wound healing, which resulted from the combination with/activation by light and protocols proposed here. 26,27,34,35 In the present report, no pain scale measurement was applied (e.g. visual analogic scale).…”

“…Relative to protocols, the number of wound healing sessions varied among studies. Ahad et al 34 used 5 sessions (10 days) to reach a substantial effect on a self-inflicted thermal injury in the palate by using a 1 W output laser, whereas da Silva Neves et al 35 used a higher dosage (60 J/ cm 2 ) with 0.3 W applied in 7 sessions to promote faster wound healing after the removal of a connective tissue graft in the palatal region. Comparing these protocols with those used in the present case was difficult.…”

Effect of Low-Level Laser Therapy in Treatment of Chemotherapy Induced Oral Mucositis

“…Cytokines play a major role in the pathogenesis of anti-cancer therapy induced OM and understanding their role may be helpful in developing management strategies. 10,22,23 Among these, are the pro-inflammatory cytokines IL-6 and TNF-α which were studied and conducted in more than one study, [22][23][24] in which they examined the impact of LLLT on inflammatory cytokines during COM among patients undergoing hematopoietic stem cell transplantation. They found a significant difference in plasma level of IL-10 only.…”

Heat injured stromal cells‐derived exosomal EGFR enhances prostatic wound healing after thulium laser resection through EMT and NF‐κB signaling

“…In skin wound healing, it is known that this process is complicated and depends on many different cell types and their interactions in sophisticated temporal sequences . Previous studies have revealed that low‐level laser therapy (LLLT) effectively improved wound healing through the promotion of the cell cycle, whereas heat injuries upregulated the expression of heat shock proteins and increased cell viability . Shallow heat injury was also reported to manipulate the XIST/miR‐29a/LIN28A pathway to restore normal tissue morphology and functions …”