Healing patterns of choroidal tubercles after antitubercular therapy

Abstract

A 28-year-old female patient with disseminated tuberculosis and choroidal tubercles on a regimen of systemic antitubercular therapy underwent fundus photography and optical coherence tomography (OCT). This was carried out monthly until complete healing of the tubercle was seen. The tubercle consisted of a central white-yellow core, consistent with choroiditis, with a faint hyperpigmentation surrounding it. There was a surrounding diffuse rim of inflammation. By the second month, the hyperpigmented rim was more prominent as were the outer edges of both the central core and the outer rim. Over time, the outer rim had largely faded with concurrent scar formation in the core. The initial OCT analysis revealed a raised RPE-choriocapillaris complex. With healing, there was a marked reduction in the choroidal lesional height suggesting resolution.

Coexistent miliary tuberculosis of choroid and tubercular panuveitis: A report

“…Mehta has recently published photographic and optical coherence tomography based healing patterns of choroidal tubercles. [ 2 ] However, serial photographic documentation of this disease entity is not available widely. Our case shows two different presentations occurring simultaneously in the two eyes from the same patient that is rarely reported.…”

Infectious uveitis: an Asian perspective

“…1). A choroidal granuloma may clinically resemble non-inflammatory conditions such as central serous chorioretinopathy, choroidal metastases, melanoma of the choroid, and other non-uveitic entities such as age-related macular degeneration [4,23,27,28]. The subretinal abscesses are more yellowish in color than a small choroidal granuloma and may have overlying retinal hemorrhages [29].…”

“…On ICGA, subretinal abscesses appear hypofluorescent throughout the early as well as late phase [30][31][32]. OCT is useful in detecting exudative retinal detachment associated with choroidal granulomas [28,33]. Enhanced-depth imaging OCT (EDI-OCT) shows choroidal changes that correlate well with the findings on indocyanine green angiography (ICGA).…”