Healing Septal Perforations by Secondary Intention Using Acellular Dermis as a Bioscaffold

Sharma, Ayushman; Janus, Jeffrey R.; Diggelmann, Henry R.; Hamilton, Grant

doi:10.1177/0003489414565002

Cited by 12 publications

(6 citation statements)

References 20 publications

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“…More recently, we described a simplified technique for closing perforations by relying on healing by secondary intention. 19 Interesting methods continue to be proposed for surgical closure of nasal septal perforations with impressive results. There continue to be reports of the use of the advancement 7 and rotation flaps.…”

Section: Treatment Options For Patients With Septal Perforationsmentioning

confidence: 99%

Three-dimensional Printing of Large Nasal Septal Perforations for Optimal Prosthetic Closure

Altunay

Bly

Edwards

et al. 2016

Am J Rhinol�Allergy

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Section: Treatment Options For Patients With Septal Perforationsmentioning

confidence: 99%

Three-dimensional Printing of Large Nasal Septal Perforations for Optimal Prosthetic Closure

Altunay

Bly

Edwards

et al. 2016

Am J Rhinol�Allergy

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“…Silastic sheets help to prevent the crust formation on repair sites and provide a moist microenvironment, resulting in a well-healed septum. 4,11,30,31 Silastic sheeting is usually secured in place for at least 3 weeks, but may be kept on nasal septum until the perforation is fully healed. 4 The healing process can be monitored postoperatively through the transparent silastic sheet at each visit.…”

Section: Discussionmentioning

confidence: 99%

Long-Term Outcomes of Nasoseptal Perforation Repair Using Anterior Maxillary Sinus Wall as an Interpositional Graft

Hwang

Han

Kang

et al. 2021

Am J Rhinol�Allergy

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Background Various graft materials have been used to repair nasoseptal perforation, but there is no standardized treatment method. The anterior maxillary sinus wall is flattened in appearance and can be easily obtained in a sufficient amount for a large-sized nasoseptal perforation. Objectives The aim of this study is to determine whether the anterior maxillary sinus wall is suitable as an interpositional graft in the surgical repair of septal or nasoseptal perforation. Methods This is a retrospective review of 21 patients who underwent repair of nasoseptal perforation using anterior maxillary sinus wall as an interpositional graft. The etiology, pre- and post-operative NOSE and GBI score, and perforation size were reviewed. The surgical outcome was considered successful if total closure was achieved after postoperative follow-up. Results 19 of the 21 perforations were successfully repaired with anterior maxillary sinus wall. Failure of the repair was found in 2 patients. Causal etiology of perforation was previous septoplasty in 10 patients, and electrocautery in 1 case, but not identified in 10 cases. The largest size was 2.7 × 2.2 cm. The most common symptoms were epistaxis, crusting, and nasal obstruction. Closure of septal perforation resulted in improved subjective symptoms and quality of life which were evaluated with NOSE and GBI score. Conclusion Anterior maxillary sinus wall as interpositional graft between mucoperichondrial flaps can be used to reliably repair nasoseptal perforations.

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“…15 Additionally, small nasal defects have been shown to heal secondarily with 2D acellular dermis scaffold reconstruction, paving the way for more complex defect closure with 3D dermal scaffolds. 24 3D bioprinting—directly depositing cellular suspensions into biocompatible scaffolds—has shown promise for rhinoplasty in its ability to recreate nasal cartilage. 15 25 Chondrocyte-bio printed nasal cartilage scaffolds have demonstrated neocartilage formation with de novo collagen and extracellular matrix deposition, as well as mechanical properties similar to native nasal cartilage.…”

Section: D Modeling and Tissue Engineeringmentioning

confidence: 99%

Three-Dimensional Technology in Rhinoplasty

et al. 2022

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Rhinoplasty is uniquely suited to capitalize on different aspects of three-dimensional (3D) modeling technology. Currently, 3D surface imaging of preoperative and postoperative nasal structure provides a platform for better surgical planning and patient counselling as well as objective postoperative measurements. Physical nasal models using 3D printing technology can improve rhinoplasty performance intraoperatively, postoperative outcomes, together with nasal prosthetic manufacture, by tailoring to specific patient anatomy. Advances in tissue engineering using 3D-printed biocompatible scaffolds have shown excellent nasal cartilage mimicry and hold promise for increasingly versatile directed tissue regeneration in rhinoplasty and nasal reconstructive surgery. As health care innovations are expected to become increasingly common in standard rhinoplasty practices in the future, we give an account of how 3D technologies can create new opportunities to optimize surgical planning and improve overall the patient experience.

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Healing Septal Perforations by Secondary Intention Using Acellular Dermis as a Bioscaffold

Cited by 12 publications

References 20 publications

Three-dimensional Printing of Large Nasal Septal Perforations for Optimal Prosthetic Closure

Three-dimensional Printing of Large Nasal Septal Perforations for Optimal Prosthetic Closure

Long-Term Outcomes of Nasoseptal Perforation Repair Using Anterior Maxillary Sinus Wall as an Interpositional Graft

Three-Dimensional Technology in Rhinoplasty

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