Health-care workers: source, vector, or victim of MRSA?

Albrich, Werner C.; Harbarth, Stéphan Juergen

doi:10.1016/s1473-3099(08)70097-5

Cited by 461 publications

(511 citation statements)

References 171 publications

Supporting

Mentioning

458

Contrasting

Unclassified

Order By: Relevance

“…However, routine screening is not recommended, unless healthcare personnel are epidemiologically associated with ongoing transmission. 20,[250][251][252] In contrast, healthcare personnel without CF who develop symptomatic MRSA infections (eg, draining wounds, sinusitis with drainage, and superinfection of chronic dermatitis) should be placed on administrative leave, treated until no longer infectious, and obtain clearance from the facility's occupational health service before returning to work. 5,8 Other nonhealthcare settings, including sports teams.…”

Section: Iiib2 S Aureusmentioning

confidence: 99%

Infection Prevention and Control Guideline for Cystic Fibrosis: 2013 Update

Saiman

Siegel

LiPuma

et al. 2014

Infect. Control Hosp. Epidemiol.

352

382

View full text Add to dashboard Cite

The 2013 Infection Prevention and Control (IP&C) Guideline for Cystic Fibrosis (CF) was commissioned by the CF Foundation as an update of the 2003 Infection Control Guideline for CF. During the past decade, new knowledge and new challenges provided the following rationale to develop updated IP&C strategies for this unique population:1. The need to integrate relevant recommendations from evidence-based guidelines published since 2003 into IP&C practices for CF. These included guidelines from the Centers for Disease Control and Prevention (CDC)/Healthcare Infection Control Practices Advisory Committee (HICPAC), the World Health Organization (WHO), and key professional societies, including the Infectious Diseases Society of America (IDSA) and the Society for Healthcare Epidemiology of America (SHEA). During the past decade, new evidence has led to a renewed emphasis on source containment of potential pathogens and the role played by the contaminated healthcare environment in the transmission of infectious agents. Furthermore, an increased understanding of the importance of the application of implementation science, monitoring adherence, and feedback principles has been shown to increase the effectiveness of IP&C guideline recommendations.2. Experience with emerging pathogens in the non-CF population has expanded our understanding of droplet transmission of respiratory pathogens and can inform IP&C strategies for CF. These pathogens include severe acute respiratory syndrome coronavirus and the 2009 influenza A H1N1. Lessons learned about preventing transmission of methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant gram-negative pathogens in non-CF patient populations also can inform IP&C strategies for CF.

show abstract

Section: Iiib2 S Aureusmentioning

confidence: 99%

Infection Prevention and Control Guideline for Cystic Fibrosis: 2013 Update

Saiman

Siegel

LiPuma

et al. 2014

Infect. Control Hosp. Epidemiol.

352

382

View full text Add to dashboard Cite

show abstract

“…49 Albrich et al recently published a systematic review revealing 18 studies showing proven transmission, and 26 studies showing likely transmission, to patients from MRSA-colonized HCWs. 50 The latter review suggested that screening of HCWs should not be restricted to outbreak settings because there is a trend for higher colonization rates in settings where MRSA is endemic. 50 Others have also suggested that screening should take place irrespective of the presence of risk factors or purulent infections, as part of pre-employment examination, or even periodically and unannounced before a work shift, to avoid detecting only transient carriers.…”

Section: Active Surveillance Culture For Healthcare Workersmentioning

confidence: 99%

“…50 The latter review suggested that screening of HCWs should not be restricted to outbreak settings because there is a trend for higher colonization rates in settings where MRSA is endemic. 50 Others have also suggested that screening should take place irrespective of the presence of risk factors or purulent infections, as part of pre-employment examination, or even periodically and unannounced before a work shift, to avoid detecting only transient carriers. 49 However, implementing routine HCW screening is not feasible in many healthcare settings because of its high cost.…”

Section: Active Surveillance Culture For Healthcare Workersmentioning

confidence: 99%

“…Therefore, HCWs most frequently act as vectors and not as the main source of MRSA transmission. 50 Furthermore, HCWs may also be innocent bystanders without any role in transmission to patients, a scenario that might become increasingly frequent with rising prevalence of MRSA in the community. The dynamics of MRSA colonization in HCW are not well known and may be difficult to establish.…”

Section: Active Surveillance Culture For Healthcare Workersmentioning

confidence: 99%

“…However, many studies addressing MRSA decolonization strategies among HCWs have shown marked heterogeneity in terms of the definition of successful decolonization, the length of follow-up, and the number and source of repeated specimens. 50 Although S. aureus and MRSA decolonization may be achieved, at least in certain patient populations, further studies are required to identify more effective agents for long-term eradication of nasal and extra-nasal sites of colonization, to evaluate the efficacy of this strategy for preventing infection in various clinical situations, and to determine whether it has any significant role to play as an infection control measure. 54 For example, adequately powered, randomized controlled trials of decolonization for preventing postoperative infections in surgical patients known to be colonized with S. aureus should be conducted.…”

Section: Decolonizationmentioning

confidence: 99%

See 2 more Smart Citations

Prevention strategies for methicillin-resistant Staphylococcus aureus (MRSA) in Latin America

Labarca¹,

Salles²

2010

Braz J Infect Dis

View full text Add to dashboard Cite

After the first reports of the emergence of methicillin-resistant Staphylococcus aureus (MRSA) in the 1970s, numerous measures intended to prevent its transmission were initiated in hospitals. However, in most cases, large-scale measures failed to be implemented and the transmission of MRSA has since led to a global pandemic. Presently, doubts still remain about the best approach to prevent and control MRSA and more often than not, control measures are not implemented. Therefore, we review here the current situation in Latin America with respect to existing policies for control of MRSA, and evaluate the evidence for control measures in hospitals and the community. We look at the risk factors for infection and transmission of MRSA between hospital patients and within specific populations in the community, and at the effect of antibiotic usage on the spread of MRSA in these settings. Finally, we summarize recommendations for the prevention and control of MRSA, which can be applied to the Latin American hospital environment and community setting.

show abstract

Patients With Infectious Diseases, Overcrowding, and Health in Hospital Staff

Virtanen¹

2011

Arch Intern Med

View full text Add to dashboard Cite

torials, and protocols; and watch laboratory video tutorials (Figure and eFigure 2).Smartphone-attached "laboratory on chip" (LOC) devices with modular microfluidic chips based on optoelectrowetting technology can perform sample preparation and detection steps in a simple and automated manner; LOC devices to run capillary electrophoresis, real-time polymerase chain reaction, flow cytometry, enzymatic assays, biomarker screening, and immunoassays have been developed. 8,9 Outlook. Real-time medical and scientific communication and information is already at our fingertips, literally. A breakthrough will be "biocommunicators" incorporating a whole new dimension of information. Feasible potential applications include population-based cancer screening; prediction of drug response for biological or targeted therapies using genetic polymorphisms; environmental monitoring; on-site and bedside detection of critical laboratory and drug values on house calls by emergency responders; as well as clinical research with homebased collection of real-life biomedical data and FDA (Food and Drug Administration)-demanded patientreported outcomes.

show abstract

Health-care workers: source, vector, or victim of MRSA?

Cited by 461 publications

References 171 publications

Infection Prevention and Control Guideline for Cystic Fibrosis: 2013 Update

Infection Prevention and Control Guideline for Cystic Fibrosis: 2013 Update

Prevention strategies for methicillin-resistant Staphylococcus aureus (MRSA) in Latin America

Patients With Infectious Diseases, Overcrowding, and Health in Hospital Staff

Contact Info

Product

Resources

About