Health economic evaluation of patients with sepsis after gastrointestinal tumor surgery—a cost consequences analysis in China

Abstract

Background: The purpose of this study was to evaluate the health economics of patients with sepsis after gastrointestinal tumor operation in ICU.Methods: This case-control study used 1:1 propensity-score (PS) matched method and patients were matched according to tumor type, age and gender. The study group was composed of 181 patients with sepsis after operation of gastrointestinal tumor in ICU, while the control group was composed of 181 patients without sepsis after operation of gastrointestinal tumor. The medical expenses and length of stay in the hospital of these patients were analyzed. Results:The median of the total hospitalization cost for the study group was $26,038, which was 1.7 times of the control group (P<0.001). The costs of drugs, laboratory test, examination, treatment, operation, anesthesia, materials, ward and other costs in the study group were higher than those in the control group (P<0.001). The median length of stay in the hospital in the study group was 26 days, which were 12 days longer than that of the control group (P<0.001). However, there was no significant difference in daily average cost between the two groups (P=0.103). Conclusions:In ICU, patients with sepsis after operation of gastrointestinal tumor increased the cost of hospitalization and prolonged the length of stay in the hospital than those without sepsis.

Effects of Shenling Chengqi Decoction on Gastrointestinal Function and Immune Status of Patients with Gastrointestinal Injury in Severe Sepsis

“…(5) Give patients reasonable oxygen therapy. (6) Give early enteral or parenteral nutrition support, and actively supplement glutamine and probiotics. (7) For those who are unable to tolerate the treatment of emotional irritability, appropriate sedative drugs should be given to ICU.…”

“…The original inflammatory reaction was expanded, causing damage to the body again and accelerating the development of sepsis. At present, the treatment methods of western medicine for gastrointestinal dysfunction mainly include preventing and correcting intestinal flora disorder, promoting intestinal motility drugs, promoting mucosal repair drugs, and restoring intestinal nutrition as soon as possible, but they cannot achieve satisfactory results [ 6 ]. Therefore, there is an urgent need for new treatment ideas and methods in clinic.…”