Health Effects Associated with Welding

Antonini, James M.

doi:10.1016/b978-0-08-096532-1.00807-4

Cited by 30 publications

(28 citation statements)

References 146 publications

(122 reference statements)

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“…8,9 It is estimated that more than 110 million workers across the world are subject to some form of weldingrelated exposure, whether they are full-time welders or employed in other industries such as construction, farming, ship-building or vehicle servicing. 3,10 Welders are exposed to a number of direct hazards including high heat and radiation, as well as respiratory, cardiovascular and reproductive hazards through inhalation of carcinogenic welding fumes. Dermal toxicity from welding-associated UVR is also a concern.…”

Section: Ultraviolet Radiation Exposure In Weldingmentioning

confidence: 99%

“…3 It is known that welders are exposed to the full UV spectrum, including UVA, UVB and UVC radiation, artificially from the welding arc. 8,9 Notably, the UVR from the welding arc can result in erythema of unprotected areas of the welder's skin, particularly in the head and neck region, 10 and many welders also experience burns from radiation or flying sparks and hot metal. 11 The severity of such erythema or burns depends on factors such as distance from the source, susceptibility of the host, use of protective clothing, exposure time and wavelength.…”

Section: Ultraviolet Radiation Exposure In Weldingmentioning

confidence: 99%

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Skin cancer and welding

Falcone

Zeidler-Erdely

2018

Clin Exp Dermatol

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Summary Many workers in several different occupations can be exposed to ultraviolet radiation (UVR), which may increase their risk of developing skin cancer. Welding, an occupation employing an estimated 11 million people worldwide, is one such occupation. Welders are known to be exposed to the full spectrum of UVR from the welding arc and often experience burns and localized cutaneous erythema. In 2017, UVR from welding was classified as carcinogenic to humans based on sufficient evidence of ocular melanoma in humans. It has been hypothesized that exposure to UVR from the welding arc also may increase the risk of skin cancer among workers in this occupation. This review summarizes the current literature on skin cancer risk in welders.

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Section: Ultraviolet Radiation Exposure In Weldingmentioning

confidence: 99%

Section: Ultraviolet Radiation Exposure In Weldingmentioning

confidence: 99%

Skin cancer and welding

Falcone

Zeidler-Erdely

2018

Clin Exp Dermatol

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“…The chemical composition of welding fumes is highly dependent on the welding technique; the type of welding electrode, the flux material added to the electrode, the technological conditions and the type of base material to be welded [1,6]. Epidemiological studies suggest that welders have an increased risk for developing lung cancer [1,[7][8][9][10]. Welding fumes, especially fumes generated during stainless steel welding, may contain considerable amounts of hexavalent chromium (Cr(VI)).…”

Section: Introductionmentioning

confidence: 99%

“…During the welding procedure, metals are vaporized followed by condensation into very fine particles [1][2][3][4][5]. The chemical composition of welding fumes is highly dependent on the welding technique; the type of welding electrode, the flux material added to the electrode, the technological conditions and the type of base material to be welded [1,6].…”

Section: Introductionmentioning

confidence: 99%

Simultaneous speciation analysis of chromate, molybdate, tungstate and vanadate in welding fume alkaline extracts by HPLC–ICP-MS

Ščančar

Berlinger

Thomassen

et al. 2015

Talanta

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“…Because welding processes generate inhalable metal fumes, welders are at risk for the development for adverse cardiovascular effects. Until recently, few reports on the study of cardiovascular health in welders existed (Sjögren et al, 2002; Ibfelt at al., 2010; Scharrer et al, 2007; Cavallari et al, 2008; Fang et al, 2009; Erdely et al, 2011; Antonini, 2014). Most of these studies indicated that exposure to welding particles led to cardiovascular alterations.…”

mentioning

confidence: 99%

Alterations in Cardiomyocyte Function After Pulmonary Treatment with Stainless Steel Welding Fume in Rats

Popstojanov

Antonini

Salmen

et al. 2014

Journal of Toxicology and Environmental Health, Part A

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Welding fume is composed of a complex of different metal particulates. Pulmonary exposure to different welding fumes may exert a negative impact on cardiac function, although the underlying mechanisms remain unclear. To explore the effect of welding fumes on cardiac function, Sprague-Dawley rats were exposed by intratracheal instillation to 2 mg/rat of manual metal arc hard surfacing welding fume (MMA-HS) once per week for 7 wk. Control rats received saline. Cardiomyocytes were isolated enzymatically at d 1 and 7 postexposure. Intracellular calcium ([Ca2+]i) transients (fluorescence ratio) were measured on the stage of an inverted phase-contrast microscope using a myocyte calcium imaging/cell length system. Phosphorylation levels of cardiac troponin I (cTnI) were determined by Western blot. The levels of nonspecific inflammatory marker C-reactive protein (CRP) and proinflammatory cytokine interleukin-6 (IL-6) in serum were measured by enzyme-linked immunosorbent assay (ELISA). Contraction of isolated cardiomyocytes was significantly reduced at d 1 and d 7 postexposure. Intracellular calcium levels were decreased in response to extracellular calcium stimulation at d 7 postexposure. Changes of intracellular calcium levels after isoprenaline hydrochloride (ISO) stimulation were not markedly different between groups at either time point. Phosphorylation levels of cTnI in the left ventricle were significantly lower at d 1 post-exposure. The serum levels of CRP were not markedly different between groups at either time point. Serum levels of IL-6 were not detectable in both groups. Cardiomyocyte alterations observed after welding fume treatment were mainly due to alterations in intracellular calcium handling and phosphorylation levels of cTnI.

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Health Effects Associated with Welding

Cited by 30 publications

References 146 publications

Skin cancer and welding

Skin cancer and welding

Simultaneous speciation analysis of chromate, molybdate, tungstate and vanadate in welding fume alkaline extracts by HPLC–ICP-MS

Alterations in Cardiomyocyte Function After Pulmonary Treatment with Stainless Steel Welding Fume in Rats

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