Health effects from reported exposure to methamphetamine labs: A poison center-based study

Thrasher, Dennis L.; Derau, Katie Von; Burgess, Jefferey L.

doi:10.1007/bf03178267

Cited by 32 publications

(24 citation statements)

References 10 publications

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“…Effects consistent with those derived from the range of chemicals and drugs stored and used in the clandestine laboratory include: death; burns and irritation of skin, eyes, nose and throat; lacrimation; pulmonary oedema; coughing; chest pain; shortness of breath; nausea/ vomiting; dizziness; headache; anxiety; bad taste and lethargy (5,31,34,61,71,74,83,98). Exposures to high concentrations of solvents are associated with liver and kidney effects (5).…”

Section: Acute Hazards and Effectsmentioning

confidence: 90%

“…Between 25% and 40% (61,(74)(75)(76)(77) of homes seized in the US were reported to have children present. The number of children in these premises in the US has been observed to be increasing with the rate doubling between 1999 and 2002 (78).…”

Section: Childrenmentioning

confidence: 99%

“…The available data (34,61,70,73,75,88) are considered sufficient to support that a range of individuals, including children in clandestine drug laboratories are at high risk for injury and illness associated with immediate hazards such as fires, explosions and chemical incidents, as well as acute and chronic exposure to the range of chemicals used to manufacture the drugs as well as the drugs themselves.…”

Section: Health Effectsmentioning

confidence: 99%

“…A volunteer fire-fighter's lung capacity was found to decrease by 85% after attendance at an explosion at a methamphetamine laboratory (11). The available studies suggest that 93% of first-responders are likely to seek medical treatment for effects and injuries reported from methamphetamine laboratories (61). No data is available that provide results of any biological monitoring that may have been undertaken to further evaluate the potential for exposure by first-responders.…”

Section: Acute Hazards and Effectsmentioning

confidence: 99%

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Exposures associated with clandestine methamphetamine drug laboratories in Australia

Wright

Edwards

Walker

2016

Reviews on Environmental Health

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AbstractThe clandestine manufacture of methamphetamine in residential homes may represent significant hazards and exposures not only to those involved in the manufacture of the drugs but also to others living in the home (including children), neighbours and first responders to the premises. These hazards are associated with the nature and improper storage and use of precursor chemicals, intermediate chemicals and wastes, gases and methamphetamine residues generated during manufacture and the drugs themselves. Many of these compounds are persistent and result in exposures inside a home not only during manufacture but after the laboratory has been seized or removed. Hence new occupants of buildings formerly used to manufacture methamphetamine may be unknowingly exposed to these hazards. Children are most susceptible to these hazards and evidence is available in the literature to indicate that these exposures may result in immediate and long-term adverse health effects. The assessment of exposure within the home can be undertaken by measuring contaminant levels or collecting appropriate biological data from individuals exposed. To gain a better understanding of the available data and key issues associated with these approaches to the characterisation of exposure, a review of the published literature has been undertaken.

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Section: Acute Hazards and Effectsmentioning

confidence: 90%

Section: Childrenmentioning

confidence: 99%

Section: Health Effectsmentioning

confidence: 99%

Section: Acute Hazards and Effectsmentioning

confidence: 99%

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Exposures associated with clandestine methamphetamine drug laboratories in Australia

Wright

Edwards

Walker

2016

Reviews on Environmental Health

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“…Clandestine methamphetamine labs are known to produce phosphine, iodine, hydrochloric acid, various solvents, methamphetamine and methamphetamine intermediates [14]. A descriptive study performed by the Washington State Poison Control Center reported the health outcomes of people exposed to clandestine methamphetamine labs most commonly to be headaches, respiratory/eye irritation, nausea, and vomiting [15]. Interestingly, a retrospective chart evaluation of 66 police officers exposed to clandestine methamphetamine labs reported memory loss in up to 77%, but without further description [16].…”

Section: Discussionmentioning

confidence: 99%

Anterograde Amnesia after Methamphetamine Lab Exposure

Sanders¹

2016

JNSK

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Anterograde Amnesia after Methamphetamine Lab Exposure Background: Some known toxic exposures can produce detrimental cognitive deficits. Yet, very few substances have been linked to the development of anterograde amnesia. Here, we report a novel case of a middle-age man who presented with a profound and apparently permanent anterograde amnesia following his exposure to a clandestine methamphetamine laboratory. Case Report: A 47 year-old, righthanded man presented in 2013 with a history of memory loss and seizures since 2001, when he was exposed during his work as a firefighter to the fumes of spilled material intended to synthesize methamphetamine in a clandestine laboratory. Following the exposure, he suffered a major and immediate impairment of multiple cognitive domains, with anterograde memory being most impaired. A formal neurobehavioral status examination NBSE showed a profound impairment in episodic/verbal memory and lesser impairment of executive function. The patient clinical course has to date been stable without further deterioration or improvement. Discussion: This case highlights a clear temporal relationship of methamphetamine laboratory exposure and the development of deficits in memory and executive dysfunction suggestive of involvement of both prefrontalstriatal circuits and medial temporal areas. This is in concordance with prior animal studies, and warrants further investigation in the future.

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Amphetamine and Methamphetamine

Barceloux

2012

Medical Toxicology of Drug Abuse

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Health effects from reported exposure to methamphetamine labs: A poison center-based study

Abstract: Poison control center data help characterize health outcomes from exposure to suspected illicit methamphetamine labs. Many of the reported symptoms in suspected former labs are consistent with exposure to persistent irritants.

Cited by 32 publications

References 10 publications

Exposures associated with clandestine methamphetamine drug laboratories in Australia

Exposures associated with clandestine methamphetamine drug laboratories in Australia

Anterograde Amnesia after Methamphetamine Lab Exposure

Amphetamine and Methamphetamine

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