Objective
Persons with serious mental illness have an increased mortality rate and a higher burden of many medical conditions compared to those without serious mental illness, but cancer risk in the serious mental illness population is uncertain. Cancer incidence in a community-based cohort of adults with schizophrenia or bipolar disorder was examined by race, sex, and cancer site.
Methods
We calculated standardized incidence ratios of total and site-specific cancers comparing a cohort of 3317 Maryland Medicaid adult beneficiaries with schizophrenia or bipolar disorder followed from 1994 through 2004 to the U.S. population.
Results
Total cancer incidence for adults with schizophrenia or bipolar disorder was 2.6 times higher than in the U.S. population. Elevated risk in persons with serious mental illness was greatest for cancer of the lung and bronchus. No differences in risk were found for African American versus white Medicaid beneficiaries with serious mental illness.
Conclusion
These findings suggest heightened risk for cancer among adults with schizophrenia or bipolar disorder. Clinicians should promote appropriate cancer screening and work to reduce modifiable risk factors, such as smoking, among persons with serious mental illness.