Background: Health literacy (HL) is perceived as one of the most important concepts for modern health promotion activities to be successful. The research undertaken in the context of HL usually focuses on its antecedents and consequences, either for specific groups of patients or society or for the whole population. Objectives: The main aim of this study was to assess the antecedents and consequences of limited health literacy (HL) in a nationally representative sample of the Polish population. Methods: The analysis was carried out on the data obtained from a sample of 1000 Polish citizens through a telephone-based survey undertaken using a short, 16-item questionnaire developed within the European Health Literacy Project (HLS-EU). The total HLS score was calculated according to the guidelines published by the HLS-EU project. Chi2 test and logistic regression models were used for the analysis of the relationships between the variables. Results: The mean HL score (standard deviation) in the study sample was 12.99 (3.11). HL was related to age, marital and vocational status. Limited HL was associated with a lower self-assessment of health (OR, 95% CI: 2.52, 1.54-4.13), the prevalence of obesity and disability (1.71, 1.13-2.57, and 1.92, 1.25-2.94, respectively), less frequent physical activity (0.70, 0.49-0.99), a lower consumption of fruits and vegetables (0.47, 0.34-0.65), and with more frequent hospitalisations (2.02, 1.38-2.95). Conclusions: The assessment of HL using the16-item HLS-EU questionnaire may be a useful tool to enable health behaviours and utilisation of health care resources by society to be predicted.The research undertaken in the context of HL usually focuses on its antecedents and consequences, either for specific groups of patients or citizens or for the whole population. The available evidence from population studies shows that health literacy may depend on sex, age, level of education, economic and/or social status, and the type of vocational activities. In the research carried out to date, it has been demonstrated that lower HL is displayed by men rather than by women [4][5][6][7], by people having lower levels of educational attainment than by those with higher levels [4][5][6][7][8][9][10][11][12], by single people than by married people [7,13], by people with lower social status than by those with a higher status [8,11,14], by people of lower rather than those of higher economic status or income [4,[7][8][9]13,15,16] and, finally, by people living in more challenging conditions [6,8]. In most studies, there was also a general trend for HL decreasing with age [4,6,8,9,15].The efforts undertaken in the last decade resulted in a comprehensive assessment of the consequences of limited health literacy. In 2011, the updated version of the systematic review authored by Berkman et al. [16] was published. This stated that low HL might be associated with more frequent hospital admissions and the use of emergency care; lower participation in screening programmes, e.g., mammography; lower receipt of ...