Health as an inseparable part of human beings needs to be maintained to achieve a complete human health degree. The role of health literacy in attaining optimum health is significant. When associated with nursing, health literacy must be interpreted as a part of the role and function of nursing. However, to understand health literacy, it is necessary to study it from the aspect of scientific formation itself and a nursing perspective. This review proposes an alternative conceptualization of health literacy from a nursing perspective. This review used an integrative search through four databases: ScienceDirect, ProQuest, SAGE Journal, and Google Scholar. Search using various combinations of keywords with the help of Boolean operators, including: health literacy, nursing perspective, nursing, and conceptualization combined as MESH terms. The inclusion criteria are peer-reviewed articles in English that discuss health literacy and nursing perspective. Articles published within the last six years (2017-2022). Research such as literature reviews, dissertations, editorials, commentaries, and other expert opinions are excluded. Ten articles were considered in this literature review. We describe the conceptualization of health literacy from the nurse’s point of view, the predictors that influence it, the dimensions surrounding health literacy, the implication of health literacy, and how nurses will participate in supporting this health literacy. In the end, this conceptualization will be used as an illustration material to integrate the concept of health literacy into various problems that become nursing tasks.