Health metrics for helminth infections

King, Charles H.

doi:10.1016/j.actatropica.2013.12.001

Cited by 47 publications

(37 citation statements)

References 56 publications

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“…Consequently, the potential that the burden of a disease or its sequelae may be worse for those that are living in poverty is not accounted for. It has been argued that this aspect of DALY calculations may significantly underestimate the burden of poverty‐related diseases . The DALY disability weights do not fully account for the psycho‐social implications of a disease or its sequelae and its overall impact on quality of life. They also do not explicitly account for the impact of the disease on patients’ informal caregivers.…”

Section: Resultsmentioning

confidence: 99%

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Economic evaluations of onchocerciasis interventions: a systematic review and research needs

Turner

Walker

Pion

et al. 2019

Tropical Med Int Health

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Objective To provide a systematic review of economic evaluations that has been conducted for onchocerciasis interventions, to summarise current key knowledge and to identify research gaps. Method A systematic review of the literature was conducted on the 8th of August 2018 using the PubMed ( MEDLINE ) and ISI Web of Science electronic databases. No date or language stipulations were applied to the searches. Results We identified 14 primary studies reporting the results of economic evaluations of onchocerciasis interventions, seven of which were cost‐effectiveness analyses. The studies identified used a variety of different approaches to estimate the costs of the investigated interventions/programmes. Originally, the studies only quantified the benefits associated with preventing blindness. Gradually, methods improved and also captured onchocerciasis‐associated skin disease. Studies found that eliminating onchocerciasis would generate billions in economic benefits. The majority of the cost‐effectiveness analyses evaluated annual mass drug administration ( MDA ). The estimated cost per disability‐adjusted life year ( DALY ) averted of annual MDA varies between US $3 and US $30 (cost year variable). Conclusions The cost benefit and cost effectiveness of onchocerciasis interventions have consistently been found to be very favourable. This finding provides strong evidential support for the ongoing efforts to eliminate onchocerciasis from endemic areas. Although these results are very promising, there are several important research gaps that need to be addressed as we move towards the 2020 milestones and beyond.

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Section: Resultsmentioning

confidence: 99%

Section: Economic Evaluations Of Alternative Interventionsmentioning

confidence: 99%

Economic evaluations of onchocerciasis interventions: a systematic review and research needs

Turner

Walker

Pion

et al. 2019

Tropical Med Int Health

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“…However, QALYs have been criticised for the high variability of self-rated health effects across different countries and cultures that minimise comparability. 14 In conclusion, the studies by Smith et al 7 and Martindale et al 8 provide a detailed account of the numbers and the many faces of LF-related morbidity in southern Malawi, both of which remain all too often hidden. It is likely that the issues highlighted here are equally relevant for other LF-endemic areas, particularly the need for clinical surveys to define the extent of ADLA, lymphoedema and hydrocoele.…”

mentioning

confidence: 93%

Assessing numbers and faces: a prerequisite for improving access to lymphatic filariasis morbidity care

Becker

Fürst

Addiss

et al. 2015

Trans R Soc Trop Med Hyg

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Concerted efforts to eliminate lymphatic filariasis worldwide have registered success; multiple rounds of mass drug administration have led to the interruption of transmission in many previously endemic areas. However, the management of patients with established clinical disease (e.g., lymphoedema, hydrocoele and acute dermatolymphangioadenitis) has not been addressed sufficiently. Two recent studies from Malawi underscore the need for accurate epidemiological and clinical data, and comprehensive morbidity assessments across various domains of daily life. Addressing these issues will guide the implementation of programmes to improve access to treatment and disability prevention for affected individuals in Malawi and beyond.

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“…Although there are effective treatments for helminthic and protozoan infections, it appears that access to treatment is not always available to the public in endemic areas [4]. Among the intestinal protozoa responsible for important diseases in public health worldwide and in Brazil, there are: Entamoeba hystolitica [5,6] and Giardia lamblia [7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Quality of life of patients with intestinal parasites assessed through a logistic regression model

Cavalcante¹,

Melo²,

Pequeno³

et al. 2016

Int Arch Med

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Introduction: The agents that cause intestinal parasitic diseases are protozoa and helminthes, through the involvement of the intestine of living beings. The concern about such diseases arises from the consequences caused in man, after installed in the body, and the symptoms they cause, such as nausea and vomiting. It is noteworthy that the intestinal parasitic diseases are among the neglected diseases in Brazil. Objective: To evaluate the quality of life of patients with intestinal parasites treated at a Public Service, applying a Logistic Regression Model. Method: This is an observational, analytical study, with cross-sectional design. Data were collected in the laboratory of the service. The sample consisted of 135 patients, aged 18-59 years, who had request for stool analysis. Their invitation occurred through an individual approach and, then, they received the Quality of Life Questionnaire SF-36. Results: The sample consisted of 135 patients: 80 had diagnosis of some intestinal parasitic disease-56 had the pathogenic form and 24, intestinal commensals. Statistical analysis revealed that, among the studied variables, the type of animal; marital status; constipation; functional capacity domain; pain domain; mental health domain; vomiting and abdominal colic, provided evidence about which associates with the presence or absence of intestinal parasites, making the first final model.

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Health metrics for helminth infections

Cited by 47 publications

References 56 publications

Economic evaluations of onchocerciasis interventions: a systematic review and research needs

Economic evaluations of onchocerciasis interventions: a systematic review and research needs

Assessing numbers and faces: a prerequisite for improving access to lymphatic filariasis morbidity care

Quality of life of patients with intestinal parasites assessed through a logistic regression model

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