Health ministry accepts liability in Japanese HIV-infected blood row

Barker, Stephen M.; Swinbanks, David

doi:10.1038/379663a0

Nature

1996

DOI: 10.1038/379663a0

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Health ministry accepts liability in Japanese HIV-infected blood row

Stephen M. Barker¹,

David Swinbanks²

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“…In the early 1980s, unknowingly contaminated therapeutic proteins from human plasma caused widespread transmission of viruses such as human immunodeficiency virus (HIV) to people with hemophilia who received these treatments 5,6 . As a result, public trust in the plasma industry's ability to safely make these therapies declined 7,8 . To ensure that current plasma-derived, vaccine, and recombinant biotherapeutics are safe, complementary safety strategies to reduce the risk of virus contamination were developed and implemented [9][10][11] .…”

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confidence: 99%

Viral contamination in biologic manufacture and implications for emerging therapies

et al. 2020

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mentioning

confidence: 99%

Viral contamination in biologic manufacture and implications for emerging therapies

et al. 2020

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History of Public Health Crises in Japan

Imamura¹,

Ide

Yasunaga³

2007

J Public Health Pol

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In Japan, a number of serious public health crises involving environmental pollution, food-borne diseases, and health hazards due to pharmaceuticals (i.e., "Yakugai") have occurred in the past 50 years. Based on the literature, we summarize the initial investigations and the subsequent measures. Some common points emerge: (1) prolonged cause identification, (2) lack of countermeasures after the cause was identified, and (3) discrimination against victims and they contributed to spreading the damage. We identify lack of corporate ethics and ill-timed disclosure of information as the principal problems in Japan's crisis-management systems. Defects in information gathering were common to all of the cases, thus we suggest necessary corrective measures, such as the establishment of a new reporting system for health hazard-related information.

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Legal, Financial, and Public Health Consequences of HIV Contamination of Blood and Blood Products in the 1980s and 1990s

Weinberg

Hounshell²,

Sherman³

et al. 2002

Ann Intern Med

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Ensuring the safety of the blood supply connects politics and science. The business and service sectors share responsibility for the collection and processing of blood donations, and government agencies perform regulatory and surveillance roles. The onset of the AIDS epidemic has challenged the interface among these systems, leading to widespread fears about compromised safety of the blood supply. Because of public concern about blood-supply decisions made in the 1980s, developed countries in the 1990s established reimbursement programs for persons with transfusion-acquired viral infections from blood or blood products, adopted diagnostic tests and procedures that improved the safety of the blood supply, and held criminal judicial investigations of government officials and industry leaders accused of delaying implementation of potential blood-safety measures. In contrast, developing countries continue to struggle with blood-supply safety issues. This paper summarizes the current status of these safety concerns in developed countries, where viral transmission from contaminated blood or blood products is extremely rare, and in developing countries, where up to 10% of HIV infections result from transfusion of blood or blood products.

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Health ministry accepts liability in Japanese HIV-infected blood row

Cited by 3 publications

References 0 publications

Viral contamination in biologic manufacture and implications for emerging therapies

Viral contamination in biologic manufacture and implications for emerging therapies

History of Public Health Crises in Japan

Legal, Financial, and Public Health Consequences of HIV Contamination of Blood and Blood Products in the 1980s and 1990s

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