Health Ownership: A Concept Analysis

Tlusty, Gisele; Hanna, Kathleen M.

doi:10.1177/08943184211031600

Cited by 2 publications

(2 citation statements)

References 22 publications

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“…The concept of health ownership has been defined as taking control, accepting responsibility, and being accountable for one’s health [ 6 ]. Achieving health ownership involves having the necessary knowledge about one’s condition to implement and sustain behaviors that positively impact outcomes.…”

Section: Introductionmentioning

confidence: 99%

“…Achieving health ownership involves having the necessary knowledge about one’s condition to implement and sustain behaviors that positively impact outcomes. Patient education and empowerment from providers and caregivers form vital components of this process [ 6 , 7 ]. For young children, parental guidance and education through early conversations create opportunities to support them as they learn about their condition.…”

Section: Introductionmentioning

confidence: 99%

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Conversations About Congenital Clubfoot: Investigating How Parents Share Information About a Structural Diagnosis With Their Children

Baskar,

Ngnepieba,

Paul

et al. 2023

Cureus

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Background and objective Clubfoot is a common congenital musculoskeletal condition that is treated with manipulation and casting in the first few weeks of life, followed by bracing that extends into early childhood. While children typically do not recall treatment with Ponseti casting in infancy, childhood treatment and monitoring may result in a sense of heightened awareness. In light of this, this study explores how parents share information about clubfoot diagnosis and guide their children in understanding the importance of treatment. Methods Parents of clubfoot children aged 5-18 years were eligible to participate. Primary recruitment was done through social media via Facebook clubfoot support groups. Participants who gave consent completed an electronic survey and were invited to take part in a semi-structured interview to share additional experiences. Significant themes elicited from study interviews were analyzed along with survey responses. Results Survey responses were received from 74 parents, and 23 participated in the semi-structured interview. Of note, 91% of parents indicated discussing clubfoot with their children, beginning at a median age of three years. The age at which parents first discussed clubfoot with their child was significantly earlier for those who “strongly agree” that their children understand their condition versus those who “agree". Although 68% of parents indicated that receiving guidance from their orthopedic provider would be helpful for these discussions, only 18% noted receiving direct advice. Recurrent themes across interviews included being open and honest about the children's diagnosis and treatment, aiding the children in taking ownership of their diagnosis, and validating emotional responses throughout treatment. Conclusions This study provides valuable insights into initiating conversations with children about structural diagnoses like congenital clubfoot. Recurrent themes from conversations with families provide information on helpful strategies to encourage early discussions about clubfoot diagnosis and treatment to aid children in taking ownership of their diagnosis.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Conversations About Congenital Clubfoot: Investigating How Parents Share Information About a Structural Diagnosis With Their Children

Baskar,

Ngnepieba,

Paul

et al. 2023

Cureus

View full text Add to dashboard Cite

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Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma

Duraj,

Kalamian,

Zuccoli

et al. 2024

BMC Med

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Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, with a universally lethal prognosis despite maximal standard therapies. Here, we present a consensus treatment protocol based on the metabolic requirements of GBM cells for the two major fermentable fuels: glucose and glutamine. Glucose is a source of carbon and ATP synthesis for tumor growth through glycolysis, while glutamine provides nitrogen, carbon, and ATP synthesis through glutaminolysis. As no tumor can grow without anabolic substrates or energy, the simultaneous targeting of glycolysis and glutaminolysis is expected to reduce the proliferation of most if not all GBM cells. Ketogenic metabolic therapy (KMT) leverages diet-drug combinations that inhibit glycolysis, glutaminolysis, and growth signaling while shifting energy metabolism to therapeutic ketosis. The glucose-ketone index (GKI) is a standardized biomarker for assessing biological compliance, ideally via real-time monitoring. KMT aims to increase substrate competition and normalize the tumor microenvironment through GKI-adjusted ketogenic diets, calorie restriction, and fasting, while also targeting glycolytic and glutaminolytic flux using specific metabolic inhibitors. Non-fermentable fuels, such as ketone bodies, fatty acids, or lactate, are comparatively less efficient in supporting the long-term bioenergetic and biosynthetic demands of cancer cell proliferation. The proposed strategy may be implemented as a synergistic metabolic priming baseline in GBM as well as other tumors driven by glycolysis and glutaminolysis, regardless of their residual mitochondrial function. Suggested best practices are provided to guide future KMT research in metabolic oncology, offering a shared, evidence-driven framework for observational and interventional studies.

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Health Ownership: A Concept Analysis

Cited by 2 publications

References 22 publications

Conversations About Congenital Clubfoot: Investigating How Parents Share Information About a Structural Diagnosis With Their Children

Conversations About Congenital Clubfoot: Investigating How Parents Share Information About a Structural Diagnosis With Their Children

Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma

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