Health‐related issues in individuals with agenesis of the corpus callosum

Doherty, D.; Tu, Shihfen; Schilmoeller, Kathryn J.; Schilmoeller, Gary L.

doi:10.1111/j.1365-2214.2006.00602.x

Cited by 53 publications

(51 citation statements)

References 18 publications

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“…This problem may reflect some other as yet unknown disorder not visible in an MRI that is typically associated with ACC (unrelated to absence of the corpus callosum). Doherty and colleagues [72] report that children with ACC have significantly more problems getting to sleep, waking up in the night, and enuresis than their siblings who have a corpus callosum.…”

Section: Cbcl Resultsmentioning

confidence: 99%

Social and Behavioral Problems of Children with Agenesis of the Corpus Callosum

Badaruddin

Andrews

Bölte

et al. 2007

Child Psychiatry Hum Dev

141

116

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Archival data from a survey of parent observations was used to determine the prevalence of social and behavioral problems in children with agenesis of the corpus callosum (ACC). Parent observations were surveyed using the Child Behavior Checklist (CBCL) for 61 children with ACC who were selected from the archive based on criteria of motor development suggesting a relatively high general level of functioning. Younger children with ACC (ages 2-5) were rated as primarily having problems with sleep. Older children with ACC (ages 6-11) manifested problems in attention, social function, thought, and somatic complaints. The older children with ACC were also compared to CBCL data from 52 children with autism who were selected from a previous study. Children with ACC were generally less impaired than children with autism on nearly all scales, with significantly less severe problems in the areas of attention, anxiety/depression, social function, and unusual thoughts. A further questionnaire related to diagnostic criteria for autism indicated that some children with ACC had traits that are among those that contribute to the diagnosis of autism within the domains of social interaction and social communication, but fewer who manifest repetitive and restricted behaviors.

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Section: Cbcl Resultsmentioning

confidence: 99%

Social and Behavioral Problems of Children with Agenesis of the Corpus Callosum

Badaruddin

Andrews

Bölte

et al. 2007

Child Psychiatry Hum Dev

141

116

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“…These two anomalies were more frequent in patients with hearing loss -in particular cleft palate. Although hearing loss related with recurring otitis has been reported as being more frequent in patients with agenesis of the corpus callosum compared to normal individuals 23 , in the present study this type of alteration appeared to be related with cleft palate, which is a known risk factor for conduction hearing loss 17,24 . Few of the study subjects had altered peripheral auditory pathways (the middle ear and cochlea).…”

Section: Discussionmentioning

confidence: 39%

Frontonasal dysplasia: clinical evaluation on audiological and brainstem electrophysiological profiles

Antoneli¹,

Giacheti²,

Genaro³

et al. 2011

Braz. j. otorhinolaryngol. (Impr.)

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Front onasal dysplasia (FND) is a rare malformative complex affecting the frontal portion of the face, the eyes and the nose; it may occur singly or associated with other clinical signs. No systematic studies describing hearing in this condition were found. Aim:To evaluate hearing sensitivity and sound stimulus conduction from cochlea to brainstem in patients with clinical signs of FND.Methods: 21 patients with isolated or syndromic FND were submitted to a clinical (otological/ vestibular antecedents and otoscopy) and instrumental (pure tone and speech audiometry, tympanometry and brainstem auditory evoked response) hearing evaluation.Design: A clinical, cross-sectional observational prospective study. Results:Hearing thresholds were normal in 15 (70%) patients, abnormal in 5 (25%), mostly with conductive hearing loss; one patient did not cooperate with testing. The tympanometric curve was type A in 30 (72%) ears, type C in 5 (12%), type As in 4 (9%) and type B in 3 (7%). The auditory brainstem response (ABR) showed no abnormalities. Conclusion:Patients with FND showed no abnormalities in the auditory system from cochlea to brainstem in this study. Mild conductive hearing loss found in some is probably related to cleft palate. Further evaluation of hearing pathways at higher levels is recommended. Braz J Otorhinolaryngol. 2011;77(5):611-5. ORIGINAL ARTICLE BJORL

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“…[6] Children with callosal conditions experience motor impairments such as hypotonia, spasticity, poor motor coordination and cerebral palsy. [7] Epilepsy and seizures are more common in these children and adolescents, with the reported prevalence varying from 27 to 86% depending on the population studied. Researchers have also reported early sucking, chewing, and swallowing difficulties and esophageal reflux.…”

Section: Discussionmentioning

confidence: 99%

Corpur Callosum Dysgenesis : A Case Report

Gursale¹,

Gursale²

2015

jemds

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Agenesis of corpus callosum can have various neuropsychiatric and developmental manifestations. Following case report highlights the case of a young female child presenting with features of not ability to hold head and delayed speech. The child showed no other positive findings and is conscious and oriented at the time of examination. Following this complains the patient was subjected for a non-contrast MRI. Neuroimaging revealed agenesis of corpus callosum. There were no other findings which could explain the current situation experienced by the patient.

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Health‐related issues in individuals with agenesis of the corpus callosum

Abstract: These data raise important questions for future research and suggest the need for increased vigilance by caregivers and health-care professionals of individuals with callosal disorders. Early detection and intervention may help prevent or ameliorate health problems in this population.

Cited by 53 publications

References 18 publications

Social and Behavioral Problems of Children with Agenesis of the Corpus Callosum

Social and Behavioral Problems of Children with Agenesis of the Corpus Callosum

Frontonasal dysplasia: clinical evaluation on audiological and brainstem electrophysiological profiles

Corpur Callosum Dysgenesis : A Case Report

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