Health-Related Quality of Life Among Patients With Peripheral Arterial Disease

Maksimović, M.; Vlajinac, Hristina; Marinković, Jelena; Kocev, Nikola; Voskresenski, Tatjana; Radak, Djordje

doi:10.1177/0003319713488640

Cited by 46 publications

(37 citation statements)

References 35 publications

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“…27 The association of impaired physical function and HRQoL with PAD, with or without symptoms, has been reported. 28,29 In our study, patients with borderline ABI had worse HRQoL and lower scores in all EQ-5D (mobility, self-care and usual activity) except for anxiety/depression and pain/discomfort compared to those with normal ABI. Other researchers have also reported poorer HRQoL in individuals with borderline ABI than in those with normal ABI.…”

Section: Discussionmentioning

confidence: 49%

Borderline ankle–brachial index is associated with increased prevalence of micro- and macrovascular complications in type 2 diabetes: A cross-sectional analysis of 12,772 patients from the Joint Asia Diabetes Evaluation Program

Yan¹,

Zhang

Kong³

et al. 2015

Diabetes and Vascular Disease Research

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Borderline ankle-brachial index is increasingly recognised as a marker of cardiovascular risk. We evaluated the impact of borderline ankle-brachial index in 12,772 Chinese type 2 diabetes patients from the Joint Asia Diabetes Evaluation Program between 2007 and 2012. Cardiovascular risk factors, complications and health-related quality of life were compared between patients with normal ankle-brachial index (1.0-1.4), borderline ankle-brachial index (0.90-0.99) and peripheral arterial disease (ankle-brachial index < 0.9). The prevalence of peripheral arterial disease and borderline ankle-brachial index was 4.6% and 9.6%, respectively. Borderline ankle-brachial index patients were older, more likely to be smokers and hypertensive, had longer duration of diabetes, poorer kidney function and poorer health-related quality of life than patients with normal ankle-brachial index. After adjustment for traditional cardiovascular risk factors, borderline ankle-brachial index was an independent predictor of diabetes-related micro-and macrovascular complications including retinopathy (odd ratios: 1.19 (95% confidence interval: 1.04-1.37)), macroalbuminuria (1.31 (1.10-1.56)), chronic kidney disease (1.22 (1.00-1.50)) and stroke (1.31 (1.05-1.64)). These findings suggest that patients with diabetes and borderline ankle-brachial index are at increased cardiovascular risk and may benefit from more intensive management.

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Section: Discussionmentioning

confidence: 49%

Borderline ankle–brachial index is associated with increased prevalence of micro- and macrovascular complications in type 2 diabetes: A cross-sectional analysis of 12,772 patients from the Joint Asia Diabetes Evaluation Program

Yan¹,

Zhang

Kong³

et al. 2015

Diabetes and Vascular Disease Research

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show abstract

“…However, the difference in all other domains also clearly exceeded the minimum clinically relevant difference of 4 points. It seems to be a general finding that subjects with PAD report an impaired generic health status; this has been demonstrated using the Medical Outcomes Study 36-Item Short-Form Health Survey (46). Although differences in generic health status, as measured by EQ-5D-3L, were statistically significant in the current study, their clinical relevance might be disputable.…”

Section: Original Articlementioning

confidence: 55%

Peripheral Artery Disease and Its Clinical Relevance in Patients with Chronic Obstructive Pulmonary Disease in the COPD and Systemic Consequences–Comorbidities Network Study

Houben-Wilke

Jörres

Bals

et al. 2017

Am J Respir Crit Care Med

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Rationale: Knowledge about the prevalence of objectively assessed peripheral artery disease (PAD) and its clinical relevance in patients with chronic obstructive pulmonary disease (COPD) is scarce.Objectives: We aimed to: (1) assess the prevalence of PAD in COPD compared with distinct control groups; and (2) study the association between PAD and functional capacity as well as health status.Methods: The ankle-brachial index was used to diagnose PAD (ankle-brachial index < 0.9). The 6-minute-walk distance, health status (St. George's Respiratory Questionnaire), COPD Assessment Test, and EuroQol-5-Dimensions were assessed in patients enrolled in the German COPD and Systemic Consequences-Comorbidities Network cohort study. Control groups were derived from the Study of Health in Pomerania. Conclusions: In a large cohort of patients with COPD, 8.8% were diagnosed with PAD, which is higher than the prevalence in control subjects without COPD. PAD was associated with a clinically relevant reduction in functional capacity and health status.

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“…These data are similar to those found in literature. Indeed, patients with ischemic or hypertrophic cardiomyopathy, atrial fibrillation or obliterative arteriopathy have an impaired QOL compared to the general population and patients undergoing valve replacement have a better QOL after surgery [31][32][33][34].…”

Section: Resultsmentioning

confidence: 99%

Quality of life of patients treated for giant cell arteritis: a case-control study

et al. 2017

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The objective of the study was to assess the quality of life (QOL) of patients with giant cell arteritis (GCA), following high dose of corticosteroids (CS). Thirty patients with GCA who had stopped CS or who were under long-term low dose of CS were included and matched to 60 controls. QOL was measured by the SF-36 score and a specific questionnaire. GCA patients had no impairment of QOL compared to controls according to SF-36. Most of them (57%) estimated that their general condition was improved following treatment. Patients with GCA complications or CS therapy side effects had no significant impairment of their QOL compared with patients without complications or adverse effects. Only the patients who had gained weight had a lower score on the domain "Vitality" (VT; p = 0.013). Walking difficulties were the most frequent complaints. They were associated with impaired scores on the physical summary score (p = 0.0340) and on the "General Health" (GH; p = 0.005) and "Physical Functioning" (PF, p = 0.0298) domains. Falls among GCA patients were associated with altered scores on the domain VT (p = 0.0058) and on the mental summary score if they had fallen at least three times (p = 0.0460). GCA patients following high dose of CS or under long-term low doses of CS have no significant impairment of their QOL compared to controls. GCA complications, including visual impairment, do not seem to have any major impact on QOL.

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Health-Related Quality of Life Among Patients With Peripheral Arterial Disease

Cited by 46 publications

References 35 publications

Borderline ankle–brachial index is associated with increased prevalence of micro- and macrovascular complications in type 2 diabetes: A cross-sectional analysis of 12,772 patients from the Joint Asia Diabetes Evaluation Program

Borderline ankle–brachial index is associated with increased prevalence of micro- and macrovascular complications in type 2 diabetes: A cross-sectional analysis of 12,772 patients from the Joint Asia Diabetes Evaluation Program

Peripheral Artery Disease and Its Clinical Relevance in Patients with Chronic Obstructive Pulmonary Disease in the COPD and Systemic Consequences–Comorbidities Network Study

Quality of life of patients treated for giant cell arteritis: a case-control study

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