Health‐related quality of life among adolescents: a comparison between subjects at risk for psychosis and other help seekers

Abstract

Adolescents at risk for psychosis have a poorer HRQoL index than other help seekers and they also differ in several sub-items, particularly in the lower scores in mental function. In the future, these findings should be considered in the care of adolescents at risk for psychosis.

Lower functioning predicts identification of psychosis risk screening status in help‐seeking adolescents

“…According to previous findings and our previous studies, [25][26][27][28][29] we hypothesize that poor functioning ability is an independently associated factor for psychosis risk screening status. To our knowledge, there is no previous studies that have included all these associated factors and assessed how they may interact.…”

“…14 Rietdijk et al reported that mood and anxiety disorders were present in 39.1% of those cases who had been treated in secondary mental health care before the onset of psychosis. [25][26][27][28] Finally, in a previous study of our earlier study sample, 29 we reported with a moderate sample size of 80 adolescents that lower functioning ability explained at-risk status to psychosis independently after age, gender, QoL and depression were adjusted. Other longitudinal studies (that have not been able to control for treatment effects) have found a tendency for symptom reduction, suggesting a worse mental state at baseline/initial presentation to mental health services.…”

“…53 For example, Yung et al found a transition rate of 16% in 2-year follow-up; 53 Ruhrmann et al found a transition rate of 19% within 18-month follow-up; 54 Ziermans et al reported a transition rate of 15.6% within 2-year follow-up; 23 and Haroun et al reported a transition rate of 13% within 1-year follow-up. 56 Validation study of the PROD-screen suggests 75% specificity 25 0.80 (0.10) 0.87 (0.09)* Alcohol consumption (AUDIT) 3.9 (5.7) 2.9 (4.5) Depression (BDI-II) 26 18.4 (10.8) 11.9 (10.4)* Anxiety (BAI) 28 13.1 (8.0) 7.9 (6.9)* Hopelessness (BHS) 27 9. compared to the SIPS method. 56 Validation study of the PROD-screen suggests 75% specificity 25 0.80 (0.10) 0.87 (0.09)* Alcohol consumption (AUDIT) 3.9 (5.7) 2.9 (4.5) Depression (BDI-II) 26 18.4 (10.8) 11.9 (10.4)* Anxiety (BAI) 28 13.1 (8.0) 7.9 (6.9)* Hopelessness (BHS) 27 9. compared to the SIPS method.…”

EPA guidance on the early intervention in clinical high risk states of psychoses

“…This is demonstrated by their high levels of hopelessness, depression, anxiety, and poor quality of life, in comparison to other help-seeking patients and patients with first-episode psychosis [30,31,95]. In fact, they often fulfill the diagnostic criteria for other mental disorders that require treatment, in particular depression, anxiety, and substance abuse or dependence [25,42,100].…”

Subjective quality of life in At‐Risk Mental State for psychosis patients: relationship with symptom severity and functional impairment

“…In order to better understand the factors related to the worsening of sQoL in early psychosis, it is important to examine which features are already associated with poor sQoL in individuals presenting clinical high risk. Three studies have shown that sQoL is markedly lower in prodromal or At-Risk Mental State (ARMS) patients compared to healthy controls, 8 other help seekers 21 and FEP patients. 22 These findings lend support to the notion that this population is already in need for mental health care, especially considering their risk for transition to psychosis.…”