Health‐related quality of life among thyroid cancer survivors: a systematic review

Husson, Olga; Haak, Harm R.; Oranje, W.A.; Mols, Floortje; Reemst, P. H. M.; Poll‐Franse, Lonneke V. van de

doi:10.1111/j.1365-2265.2011.04114.x

Cited by 126 publications

(114 citation statements)

References 44 publications

(193 reference statements)

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“…Reduction in quality of life (QOL) after thyroid surgery is multifactorial and may include need for lifelong medication, thyroid suppression, radioactive scanning/treatment, temporary and permanent hypoparathyroidism, temporary or permanent dysphonia postoperatively, and dysphagia. [7][8][9][10][11] Voice disturbance may be identified at least temporarily in up to 80% of patients after thyroid surgery, but prevention, evaluation, and management are incompletely defined. 8 About 1 in 10 patients experience temporary laryngeal nerve injury after surgery, with longer lasting voice problems in up to 1 in 25.…”

Section: Introductionmentioning

confidence: 99%

Clinical Practice Guideline: Improving Voice Outcomes after Thyroid Surgery

Chandrasekhar

Randolph

Seidman³

et al. 2013

Otolaryngol.--head neck surg.

353

100

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Objective. Thyroidectomy may be performed for clinical indications that include malignancy, benign nodules or cysts, suspicious findings on fine needle aspiration biopsy, dysphagia from cervical esophageal compression, or dyspnea from airway compression. About 1 in 10 patients experience temporary laryngeal nerve injury after surgery, with longer lasting voice problems in up to 1 in 25. Reduced quality of life after thyroid surgery is multifactorial and may include the need for lifelong medication, thyroid suppression, radioactive scanning/treatment, temporary and permanent hypoparathyroidism, temporary or permanent dysphonia postoperatively, and dysphagia. This clinical practice guideline provides evidence-based recommendations for management of the patient's voice when undergoing thyroid surgery during the preoperative, intraoperative, and postoperative period.Purpose. The purpose of this guideline is to optimize voice outcomes for adult patients aged 18 years or older after thyroid surgery. The target audience is any clinician involved in managing such patients, which includes but may not be limited to otolaryngologists, general surgeons, endocrinologists, internists, speech-language pathologists, family physicians and other primary care providers, anesthesiologists, nurses, and others who manage patients with thyroid/voice issues. The guideline applies to any setting in which clinicians may interact with patients before, during, or after thyroid surgery. Children under age 18 years are specifically excluded from the target population; however, the panel understands that many of the findings may be applicable to this population. Also excluded are patients undergoing concurrent laryngectomy. Although this guideline is limited to thyroidectomy, some of the recommendations may extrapolate to parathyroidectomy as well.Results. The guideline development group made a strong recommendation that the surgeon should identify the recurrent laryngeal nerve(s) during thyroid surgery. The group made recommendations that the clinician or surgeon should (1) document assessment of the patient's voice once a decision has been made to proceed with thyroid surgery; (2) examine vocal fold mobility, or refer the patient to a clinician who can examine vocal fold mobility, if the patient's voice is impaired and a decision has been made to proceed with thyroid surgery; (3) examine vocal fold mobility, or refer the patient to a clinician who can examine vocal fold mobility, once a decision has been made to proceed with thyroid surgery if the patient's voice is normal and the patient has (a) thyroid cancer with suspected extrathyroidal extension, or (b) prior neck surgery that increases the risk of laryngeal nerve injury (carotid endarterectomy, anterior approach to the cervical spine, cervical esophagectomy, and prior thyroid or parathyroid surgery), or (c) both; (4) educate the patient about the potential impact of thyroid surgery on voice once a decision has been made to proceed with thyroid surgery; (5) inform the anesthesi...

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Section: Introductionmentioning

confidence: 99%

Clinical Practice Guideline: Improving Voice Outcomes after Thyroid Surgery

Chandrasekhar

Randolph

Seidman³

et al. 2013

Otolaryngol.--head neck surg.

353

100

View full text Add to dashboard Cite

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“…Os sintomas decorrentes da doença e sua terapêutica afetam o dia-a-dia dos pacientes e não aparecem de forma isolada, pois geralmente são acompanhados de sinais físicos resultantes do tratamento (14)(15) . Manifestações como fadiga, insônia, dor e depressão ocorrem com frequência (16)(17) e a convivência com essa condição de saúde é desafiadora.…”

Section: Discussionunclassified

“…Autores (25) também evidenciaram associação negativa entre a utilização de medicamentos para reposição hormonal e QV. Outros estudos que também avaliaram as repercussões do tratamento medicamentoso mostraram que os pacientes possuíam QV semelhante ou ligeiramente diminuída em comparação com a população geral (14) . Portanto, o planejamento pactuado do tratamento com o paciente e sua família é fundamental.…”

Section: Discussionunclassified

“…Vários fatores podem estar ligados a esse achado, como: estar inserido numa atividade laboral (29) ; mudanças comportamentais e de visão de mundo positivas adotadas após a vivência da neoplasia (18) , com adesão a comportamento saudáveis como a prática de atividade física (17) ; tempo decorrido após o diagnóstico e tratamento do CDT (14); suporte familiar e social (26) ; medidas de apoio financeiro garantidas pela legislação brasileira.…”

Section: Discussionunclassified

“…Uma revisão integrativa (14) , que objetivou analisar a associação entre CDT e QV, identificou resultados contraditórios. Alguns estudos mostraram que a QV apresenta-se diminuída nos sobreviventes do CDT em comparação com a população saudável ou outros grupos de referência, enquanto outros encontraram resultado oposto, assim com o presente estudo (12,30) .…”

Section: Discussionunclassified

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Avaliação Da Qualidade De Vida De Indivíduos Com Carcinoma Bem Diferenciado De Tireoide Pelo Whoqol-100

Furino

2017

Cogitare Enferm.

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RESUMO: Este estudo objetivou avaliar a qualidade de vida de pacientes em acompanhamento clínico por carcinoma bem diferenciado de tireoide, por meio do questionário WHOQOL-100. Trata-se de estudo quantitativo realizado entre março de 2015 e março de 2017 em São Carlos, SP, Brasil, descritivo e transversal, que avaliou 280 indivíduos, sendo 70 com carcinoma de tireoide e 210 controles, divididos em ≤45 e >45 anos. Os resultados mostraram que o grupo carcinoma de tireoide ≤ 45 anos apresentou prejuízo nos domínios físico (p=0,0032) e nível de independência (p<0,0001), e melhora no domínio meio ambiente (0,0138 RESUMEN: Este estudio objetivó evaluar la cualidad de vida de pacientes en seguimiento clínico por carcinoma bien diferenciado de tiroides, mediante el cuestionario WHOQOL-100. Se trata de estudio cuantitativo desarrollado entre marzo del 2015 y marzo del 2017 en São Carlos, SP, Brasil, descriptivo y trasversal, que evaluó 280 individuos, siendo 70 con carcinoma de tiroides y 210 controles, divididos en ≤45 y >45 años. Los resultados mostraron que el grupo carcinoma de tiroides ≤ 45 años presentó perjuicio en los dominios físico (p=0,0032) y nivel de independencia (p<0,0001), y mejora en el dominio medio ambiente (0,0138). El grupo con carcinoma de tiroides > 45 años presentó mejora en el dominio medio ambiente (0,0002) y calidad de vida global (p=0,00146) con relación a los controles. Eses hallazgos, frutos de un análisis amplio de la calidad de vida de pacientes con carcinoma diferenciado de tiroides, pueden contribuir a la comprensión de las repercusiones de la enfermedad y su tratamiento.

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Effect of a Change in Papillary Thyroid Cancer Terminology on Anxiety Levels and Treatment Preferences

Nickel

Barratt

McGeechan

et al. 2018

JAMA Otolaryngol Head Neck Surg

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IMPORTANCE Given evidence of overdiagnosis and overtreatment of small papillary thyroid cancers (PTCs), strategies are needed to promote the consideration of less invasive treatment options for patients with low-risk PTC. OBJECTIVE To determine the association of treatment preferences and anxiety levels for PTC with the terminology used to describe the condition. DESIGN, SETTING, AND PARTICIPANTS This randomized crossover study involved a community sample of 550 Australian men and women 18 years or older without a history of thyroid cancer. Between March 16, 2016, and July 26, 2016, participants accessed an online study that presented 3 hypothetical but clinically realistic scenarios, each of which described PTC as papillary thyroid cancer, papillary lesion, or abnormal cells. Participants were exposed to all 3 scenarios with the different terminologies, and participants were randomized by the order (first, second, or third) in which they viewed the terminologies. Data analysis was conducted from September 1, 2016, to May 15, 2017. MAIN OUTCOMES AND MEASURES Treatment choice (total thyroidectomy, hemithyroidectomy, or active surveillance), diagnosis anxiety, and treatment choice anxiety. RESULTS Of the 550 participants who completed the online study and were included in the analysis, 279 (50.7%) were female and the mean (SD) age was 49.9 (15.2) years. A higher proportion of participants (108 [19.6%]) chose total thyroidectomy when papillary thyroid cancer was used to describe the condition compared with the percentage of participants who chose total thyroidectomy when papillary lesion (58 [10.5%]) or abnormal cells (60 [10.9%]) terminology was used. At first exposure, the papillary thyroid cancer terminology led 60 of 186 participants (32.3%) to choose surgery compared with 46 of 191 participants (24.1%) who chose surgery after being exposed to papillary lesion terminology first (risk ratio [RR], 0.73; 95% CI, 0.53-1.02) and 47 of 173 participants (27.2%) after being exposed to abnormal cells (RR, 0.82; 95% CI, 0.60-1.14) terminology first. After the first exposure, participants who viewed papillary thyroid cancer terminology reported significantly higher levels of anxiety (mean, 7.8 of 11 points) compared with those who viewed the papillary lesion (mean, 7.0 of 11 points; mean difference,-0.8; 95% CI,-1.3 to-0.3) or abnormal cells (mean, 7.3 of 11 points; mean difference,-0.5; 95% CI,-1.0 to 0.01). Overall, interest in active surveillance was high and higher levels of anxiety were reported by those who chose surgery, regardless of which terminology was viewed first (mean difference, 1.5; 95% CI, 1.0-1.9). CONCLUSIONS AND RELEVANCE Changing the terminology of small PTCs may be one strategy to reduce patients' anxiety levels and help them consider less invasive management options. To curtail overdiagnosis and overtreatment in PTC, other strategies may include providing balanced information about the risks and advantages of alternative treatments.

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Health‐related quality of life among thyroid cancer survivors: a systematic review

Cited by 126 publications

References 44 publications

Clinical Practice Guideline: Improving Voice Outcomes after Thyroid Surgery

Clinical Practice Guideline: Improving Voice Outcomes after Thyroid Surgery

Avaliação Da Qualidade De Vida De Indivíduos Com Carcinoma Bem Diferenciado De Tireoide Pelo Whoqol-100

Effect of a Change in Papillary Thyroid Cancer Terminology on Anxiety Levels and Treatment Preferences

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