Health-related quality of life and hypertension: a systematic review and meta-analysis of observational studies

Trevisol, Daisson José; Moreira, Leila Beltrami; Kerkhoff, Alessandra Cristina; Fuchs, Sandra Costa; Fuchs, Flávio Danni

doi:10.1097/hjh.0b013e328340d76f

Cited by 229 publications

(219 citation statements)

References 34 publications

Supporting

Mentioning

184

Contrasting

Unclassified

Order By: Relevance

“…We also found a negative association between high blood pressure and HRQoL. Such an association has previously been found in the general population with hypertension, although the difference compared with normotensive individuals is rather small (Trevisol et al, 2011). From a clinical perspective, treatment of hypertension seems important as good blood pressure control can improve HRQoL (Zygmuntowicz et al, 2013).…”

Section: Comparisons With Other Studiessupporting

confidence: 77%

Health-related quality of life and metabolic risk in patients with psychosis

Foldemo

Wärdig

Bachrach‐Lindström

et al. 2014

Schizophrenia Research

View full text Add to dashboard Cite

Health-related quality of life was assessed using the questionnaire EQ5D, both for patients and the population, and several other health status outcomes were used. Results: At 73%, schizophrenia and schizoaffective disorder were the most common diagnoses in the patient group. The results in patients (n=903) and population (n=7238) showed significant differences in lower EQ5D among patients. According to the definition by the International Diabetes Federation (IDF), elevated blood pressure was the only metabolic risk associated with lower HRQoL in patients. Raised LDL-cholesterol levels were also significantly related to lower HRQoL. Conclusion: patients suffering from psychosis had significantly lower HRQoL regarding all components in EQ5D, except for the pain/discomfort component.Almost half of the patient group met the criteria for metabolic syndrome. According to the IDF criteria, elevated blood pressure was the only metabolic risk factor that had an impact on HRQoL.

show abstract

Section: Comparisons With Other Studiessupporting

confidence: 77%

Health-related quality of life and metabolic risk in patients with psychosis

Foldemo

Wärdig

Bachrach‐Lindström

et al. 2014

Schizophrenia Research

View full text Add to dashboard Cite

show abstract

“…11,12 A systematic review of 20 original contributions identified lower quality of life among hypertensive individuals in most but not all studies. 13 Studies that could be included in a meta-analysis, and that had HRQoL evaluated by The Short-Form Health Survey (SF)-36 À or its reduced version SF-12 À , identified lower scores among individuals with hypertension or that reported to be hypertensive. 13 The studies were very heterogeneous with regard to selection criteria and comparison groups, limiting their external validity.…”

Section: Introductionmentioning

confidence: 99%

“…13 Studies that could be included in a meta-analysis, and that had HRQoL evaluated by The Short-Form Health Survey (SF)-36 À or its reduced version SF-12 À , identified lower scores among individuals with hypertension or that reported to be hypertensive. 13 The studies were very heterogeneous with regard to selection criteria and comparison groups, limiting their external validity. Moreover, some aspects on the relationship between high blood pressure (BP) and quality of life are still unsolved.…”

Section: Introductionmentioning

confidence: 99%

Health-related quality of life is worse in individuals with hypertension under drug treatment: results of population-based study

et al. 2011

View full text Add to dashboard Cite

Patients with hypertension usually report lower healthrelated quality of life (HRQoL), but it is unclear whether this is secondary to high blood pressure (BP) per se, drug treatment or awareness of disease. In a crosssectional study using a multistage population-based sample, participants were interviewed and examined at home. Hypertension was defined by BP X140/90 mm Hg or use of BP-lowering drugs. HRQoL was assessed through the Short-Form Health Survey (SF-12) and presented as the physical component summary (PCS), mental component summary (MCS) and the SF-12 eightdomain scale. In total, 1858 individuals were evaluated, being 60.1% women, aged 52.5 ± 4.1 years old, and 39.9% men, aged 47.2±9.1 years old. Prevalence of hypertension was 34.2% (95% CI 31.5-36.9). The PCS scores for hypertensive and normotensive participants were 49.4 (CI 48.6-50.2) and 51.06 (CI 50.4-51.7) (P ¼ 0.01), respectively, and the MCS scores were 49.1 (CI 47.9-50.3) and 50.5 (CI 49.6-51.2) (P ¼ 0.06), respectively. Participants with hypertension and not using BP drugs had higher HRQoL scores (PCS 49.6; MCS 51.9) than those using BP drugs either with uncontrolled (PCS 45.3; MCS 49.4) or controlled BP (PCS 46.2; MCS 47.7; Po0.05). We concluded that individuals with hypertension have worse quality of life, particularly when their BP is controlled by drugs. This perception may lead to lower rates of adherence to treatment.

show abstract

“…[2] It is noted that the management and control of hypertension reduce morbidity and mortality, the percentage fluctuates between 5.4 and 58 % of patients with controlled hypertension, worldwide. [3] The uncontrolled hypertension may be related to worsened quality of life. [4] The relationships between patient, disease, treatment variables and HRQoL have been reported.…”

Section: Introductionmentioning

confidence: 99%

“…[5] Lower HRQoL in patients with hypertension compared with normotensive individuals has been reported recent systematic review and meta-analysis of observational studies of health-related quality of life (HRQoL) in hypertensive patients. [3] This conceptual model suggests that physiological changes due to illness or treatment can lead to symptoms which affect functional status or HRQoL. These relationships are influenced by disease-related patient characteristics and environmental variables that may affect patient perception of symptoms and changes in HRQoL.…”

Section: Introductionmentioning

confidence: 99%

Assessment of Health-Related Quality of Life among Hypertensive Patients of Loralai, Pakistan

Khan¹,

Haq²,

Riaz³

et al. 2018

JPPCM

View full text Add to dashboard Cite

Health-related quality of life and hypertension: a systematic review and meta-analysis of observational studies

Abstract: Quality of life of individuals with hypertension is slightly worse than that of normotensive individuals. The influence of high blood pressure and of the awareness to have hypertension requires further investigation.

Cited by 229 publications

References 34 publications

Health-related quality of life and metabolic risk in patients with psychosis

Health-related quality of life and metabolic risk in patients with psychosis

Health-related quality of life is worse in individuals with hypertension under drug treatment: results of population-based study

Assessment of Health-Related Quality of Life among Hypertensive Patients of Loralai, Pakistan

Contact Info

Product

Resources

About