Health-related quality of life and associated factors among people living with HIV/AIDS in Sichuan, China: A cross-sectional study

Abstract

PurposeThis study aimed to explore health-related quality of life (HRQoL) and its associated factors among people living with HIV/AIDS (PLWH) in Sichuan, China.MethodsA total of 401 PLWH were recruited from the city of Panzhihua between August 2018 and January 2019. Demographic characteristics and disease-related data were collected by self-administered questionnaires and medical system records. Health-related quality of life (HRQoL) was measured by the medical outcome study HIV health survey (MOS-HIV), which measured ten subdimensions and two summarized dimensions, the physical health summary score (PHS) and the mental health summary score (MHS). Logistic regression models were used to explore the variables independently associated with quality of life.ResultsThe PHS and MHS measured by MOS-HIV were 53.66 ± 6.80 and 51.31 ± 7.66, respectively. Younger age, higher educational level, no methadone use, higher CD4 lymphocyte counts, less symptom counts and heathy BMI significantly were associated with higher HRQOL in the univariate χ2-test analysis. Education level was found to have a significant influence on patients' quality of life, both in physical health (P = 0.022) and mental health (P = 0.002) dimensions. Younger age (P = 0.032), higher CD4 lymphocyte counts (P = 0.007), less symptom counts (P < 0.001) and health BMI level (P < 0.001) were positively related to the PHS of quality of life in the multivariable logistic regression model.ConclusionThe HRQoL of PLWH in Sinchuan Province was relatively low. Age, educational level, methadone use, CD4 lymphocyte counts, symptom counts and BMI were positively related to quality of life. This study indicates that health caregivers should pay more attention to comorbidity issues and mental health in PLWH, especially for those with lower education levels, unhealthy body mass index, more symptomatic presentation and older age.

State of mental health, sleep status, and the interaction with health-related quality of life in HIV-infected Chinese patients during the COVID-19 pandemic

“…Indeed, it has been shown that PLWHA often have a lower HRQOL than healthy people [3]. Many factors have been reported to affect the HRQOL of PLWHA, such as age, educational status, social support, economic status, stigma, CD4 lymphocyte count, antiretroviral therapy, and body mass index [4][5][6][7][8][9]. Intervention measures target these factors will contribute to improve the HRQOL for PLWHA.…”

Factors related ART adherence and quality of life in PLHIV: Mediating role of positive self-care management and brain gym

“…The quality of life experienced by PLHIV in Sinchuan Province is comparatively substandard. Several factors have been found to have a good correlation with quality of life, including age, education level, methadone use, CD4, lymphocyte count, number of symptoms, and body mass index [26]. A study with minimal variations was carried out in Zhejiang Province.…”

Measuring the health-related quality of life in HIV patients with integrase strand transfer inhibitor-based regimens in China

“…Various patient-reported outcome (PRO) measures could be utilized to support HIV management by capturing patients' ART experience accurately, evaluating and differentiating treatment strategy and predict clinical outcomes [5]. Previous studies have evaluated and found the low HRQoL and associated factors in HIV patients [6][7][8][9]. Nevertheless, majority of the studies were conducted before BIC/FTC/TAF or DTG/3TC included in NRDL and have no restriction on the regimen received.…”