Health-Related Quality of Life and Associated Factors among Women on Antiretroviral Therapy in Health Facilities of Jimma Town, Southwest Ethiopia

Weldsilase, Yetnayet Abebe; Likka, Melaku Haile; Wakayo, Tolossa; Gerbaba, Mulusew

doi:10.1155/2018/5965343

Cited by 29 publications

(48 citation statements)

References 51 publications

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“…This study also shows that the third tertile on the wealth index (or the poorest PLWHA in terms of asset possession) has a strong association with MHS, which is consistent with reports by Weldsilase et al [61] and Abebe [62] that least-wealth status is associated with poor overall HRQoL. From these reports it is very evident that a lack of assets affects the health of PLWHA as manifested psychologically in poor mental HRQoL.…”

Section: Health-related Quality Of Life (Hrqol)supporting

confidence: 91%

Health-related quality of life of people living with HIV/AIDS: the role of social inequalities and disease-related factors

Nigusso

Mavhandu-Mudzusi

2020

Preprint

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Background: Health-related quality of life (HRQoL) serves as a direct measure of individuals’ health, life expectancy and the impact that the utilization of health care has on quality of life. The purpose of this study is to assess the HRQoL of people living with HIV/AIDS (PLWHA), and to ascertain its association with the social inequalities and clinical determinants among people living with HIV in Benishangul Gumuz Regional State, Ethiopia.Methods: A cross-sectional study was conducted between December 2016 and February 2017; 390 people at two referral hospitals and three health centers participated in the study. The Patient-Reported Outcomes Measurement Information System Global Health Scale (PROMIS Global 10) was used to measure key HRQoL domains. Physical Health Summary (PHS) and Mental Health Summary (MHS) scores were employed. PHS and MHS scores below 50 (the standardized mean score) were determined to be poor and above 50 to be good. Bivariate and multivariate logistic regression analyses were used to identify factors associated with PHS and MHS scores. Results: This study included 259 (66.4%) females and 131 (33.6%) males. The PHS scores ranged from 16.2 to 67.7 with a mean of 48.8 (SD = 8.9). Almost 44.6% of the study population has a PHS score of below 50; the MHS scores ranged from 28.4 to 67.6 with a mean of 50.8 (SD = 8.1). About 41.8% of the study population has an MHS score of below 50. Unemployment, household food insecurity and comorbidities with HIV were associated with both poor PHS and poor MHS scores. Age below 25 years and being a member of Christian fellowship were inversely associated with poor PHS. The least wealth index score and CD4 count below 350 cells/mL were also associated with poor MHS. Conclusion: Overall, socioeconomic inequalities and HIV-related clinical factors play an important role in improving the HRQoL of PLWHA. Many of these determinants are alterable risk factors. Appropriate strategies can improve the holistic management of chronic HIV care and maximize PLWHAs’ HRQoL. Such strategies require the adoption of comprehensive interventions, including policies and programmes that would improve the health, wellbeing and livelihood of PLWHA.

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Section: Health-related Quality Of Life (Hrqol)supporting

confidence: 91%

Health-related quality of life of people living with HIV/AIDS: the role of social inequalities and disease-related factors

Nigusso

Mavhandu-Mudzusi

2020

Preprint

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“…The percentage of participants with good overall QOL in this study was slightly higher than the findings from similar studies conducted in Jimma town (46.5%) and Felege Hiwot referral hospital (43.6%). 14,23 This difference may be due to socioeconomic differences in the study populations and the way the outcome variables were measured. However, the overall QOL in our study was lower than in similar studies conducted in Ghana, Burkina Faso, and Central India.…”

Section: Discussionmentioning

confidence: 99%

“…This result was similar to studies carried out in Ethiopia in Jimma town public health facilities, Shewa and Addis Ababa, and in Burkina Faso. 13,19,23,32 Patients with good social support inevitably experience a better QOL and also usually comply more fully with chronic care follow-up, which in turn further improves their health and hence their QOL. Having a good overall QOL was nearly 3 times higher among patients without perceived stigma, which is consistent with the results studies carried out in Ethiopia in Mekelle and Addis Ababa, and in Iran.…”

Section: Discussionmentioning

confidence: 99%

“…12,13 In Ethiopia, a few studies have been conducted at Felege Hiwot Referral Hospital in the North of the country, and at Jimma town public health facilities, where good QOL was between 45% and 47%. 14,15 These studies indicate that sociodemographic characteristics of PLWH including age, gender, education, income/wealth index, employment status and disease-related variables, such as disease stage, opportunistic infection, CD4 count, and psychosocial characteristics, were associated with QOL. [16][17][18][19][20] The numerous studies conducted across the globe on the QOL of PLWH distinguished psychological, social relationships, environment and spiritual aspects of life.…”

Section: Introductionmentioning

confidence: 99%

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<p>Determinants of Poor Quality of Life Among Adults Living with HIV and Enrolled in Highly Active Anti-Retroviral Therapy at Public Health Facilities of Arba Minch Town Administration in Southern Ethiopia</p>

Tesemma¹,

Abate²,

Abebo³

et al. 2019

HIV

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Background: The human immunodeficiency virus (HIV) continues to be a major global public health problem with more than 35 million people worldwide infected so far. Evidence shows that HIV has been compromising the quality of life of people living with HIV (PLWH) even in this era of highly active anti-retroviral therapy (HAART). There has been little research into the quality of life of PLWH receiving HAART in Ethiopia. Purpose: The aim of this study was to assess the quality of life among PLWH attending anti-retroviral therapy at public health facilities of Arba Minch town, Southern Ethiopia, in 2019. Patients and methods: We conducted a cross-sectional study design on 391 randomly selected PLWH who were attending HAART. We used a systematic random sampling technique to select participants in public health facilities of Arba Minch town from February 16 to April 26, 2019. The interviewers administered a structured questionnaire consisting of the WHOQOL-HIV BREF tool to measure the quality of life. Socio-demographic variables of study participants were collected, together with variables related to their clinical status extracted from their clinical records. Percentage mean scores were calculated and the mean of percentage mean scores was taken as the cutoff to categorize participants into two groups representing poor and good quality of life. Simple binary logistic regression and multivariable logistic regression analyses were used to determine significant variables. All variables with p-value ≤ 0.25 in simple binary logistic regression were considered as eligible variables for multivariable logistic regression. Variables with p-value ≤ 0.05 in multivariable logistic regression were considered as predictor variables. Results: Out of the 391 enrolled adult PLWH, 184 of them (47.1%) had poor of overall quality of life status, as estimated by the WHOQOL-HIV BREF tool. Good quality of life was positively associated with recent CD4 count greater than or equal to 500 cell/mm 3 (AOR=1.96, 95% CI; 1.18-3.27), absence of depression (AOR=10.59, 95% CI; 6.16-18.21), normal body mass index (AOR=2.66, 95% CI; 1.18-3.27), social support (AOR= 6.18, 95% CI; 3.56-10.75) and no perceived stigma (AOR=2.75, 95% CI; 1.62-4.67). Conclusion: Nearly half of the adult PLWH receiving HAARTat Arba Minch town had poor quality of life. High CD4 count, lack of social support, depression, and perceived stigma were associated with poor quality of life of PLWH. PLWH should be encouraged to be part of structured social support systems, such as associations of people living with HIVand mother support groups, in order to improve their social and psychological health. The health system should give attention to counseling on chronic care adherence and nutritional support to improve the quality of life of PLWH receiving HAART.

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“…A sample size of 353 was used for our study based on an expected proportion (p = 50%) of adults on ART with good HRQOL [12]. Systematic sampling technique was used to recruit the subjects from the sampling frame using a calculated sampling interval of 13.…”

Section: Sample Size Estimation and Sampling Techniquementioning

confidence: 99%

Determinants of health-related quality of life among human immunodeficiency virus positive (HIV-positive) patients at Ahmadu Bello University teaching hospital, Zaria, Nigeria- 2015

et al. 2020

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Background: The advent of Highly Active Antiretroviral Therapy (HAART) is associated with improved clinical and laboratory outcomes resulting in prolonged life and well-being of people living with Human Immunodeficiency Virus (PLHIV). However, the needs for lifelong therapy, medications' side effects and stigma have raised concerns about their quality of life (QOL). This study assessed the determinants of Health-related quality of life (HRQOL) among HIV-positive patients at Ahmadu Bello University Teaching Hospital (ABUTH) Zaria. Methods: We conducted a cross-sectional study of 353 HIV-positive adults on HAART attending the HIV clinic of ABUTH, Zaria. The participants were recruited into the study using a systematic sampling technique. Data on sociodemographics, medical parameters, QOL and family functionality were collected using structured, intervieweradministered questionnaire. The World Health Organization (WHO) Quality of Life HIV short form instrument (WHOQOL-HIV BREF) item and Family APGAR tool were respectively used in assessing the QOL and family functionality of the participants. We performed univariate, bivariate and multivariate analysis. Results: Mean age was 39.1(±10.9) years, 239 (67.7%) were females, 208 (58.9%) were Hausa-Fulani, 240 (68.2%) married and up to 210 (59.4%) had at least a secondary education. The overall mean scores on the scale of 4-20 for HRQOL were similar in three domains: environment domain 14.5(±2.8); social relationship 14.4(±3.1) and level of independence 14.4(±2.5). Lower scores were recorded in spirituality/religion/personal beliefs 12.3(±4.3). Identified determinants of HRQOL were spousal HIV-positive status (AOR = 3.37; CI; 1.46-7.74) and high family function (AOR = 2.57; CI: 1.51-4.39). Conclusion: Having highly functional family and having HIV-positive partner were the major determinants of HRQOL. Routine family counselling and strengthening the HIV social-support network should be incorporated into the routine patients' care in HIV treatment centers.

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Health-Related Quality of Life and Associated Factors among Women on Antiretroviral Therapy in Health Facilities of Jimma Town, Southwest Ethiopia

Cited by 29 publications

References 51 publications

Health-related quality of life of people living with HIV/AIDS: the role of social inequalities and disease-related factors

Health-related quality of life of people living with HIV/AIDS: the role of social inequalities and disease-related factors

<p>Determinants of Poor Quality of Life Among Adults Living with HIV and Enrolled in Highly Active Anti-Retroviral Therapy at Public Health Facilities of Arba Minch Town Administration in Southern Ethiopia</p>

Determinants of health-related quality of life among human immunodeficiency virus positive (HIV-positive) patients at Ahmadu Bello University teaching hospital, Zaria, Nigeria- 2015

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