Health-related quality of life and its association with sociodemographic, economic, health status and lifestyles among HIV-positive patients in northern Malaysia

Chow, Ngah Kuan; Harun, Sabariah Noor; Khan, Amer Hayat

doi:10.1080/09540121.2021.1981220

Cited by 4 publications

(1 citation statement)

References 13 publications

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“…Recent studies underscored the psycho-social factors and disease-related factors in the HRQoL among PLWH during ART. For example, sociodemographic factors were strongly associated with lower HRQoL of PLWH [ 3 , 4 ]. Meanwhile, social support from community [ 5 , 6 ] and family [ 7 ] might improve HRQoL among PLWH.…”

Section: Introductionmentioning

confidence: 99%

Associations between treatment burden, self-reported treatment qualities, antiretroviral therapy obtainment, and health-related quality of life among Ugandan PLWH

Guan

2023

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Background Understanding related risk factors of health-related quality of life (HRQoL) could avoid treatment failure and provide an insight of personalized treatment approach among people living with HIV/AIDS (PLWH). The objective of this study was to identify factors associated with self-reported treatment qualities and domains of health-related quality of life (HRQoL) among PLWH in Uganda. Method Data were from “Life on antiretroviral therapy: People’s adaptive coping and adjustment to living with HIV as a chronic condition in Wakiso District, Uganda” in English. The World Health Organization Quality of Life Brief Version (WHOQOL-BREF) questionnaire was used to assess the HRQoL of 263 PLWH in the sample. Considering variance inflation factors, multiple regression analyses were performed to assess the associations between demographic factors, ART obtainment, treatment burden, and self-reported treatment qualities, associations between demographic factors, self-reported treatment qualities, and HRQoL, and association between ART obtainment and HRQoL. Controlling for the confounding effects, several regression anatomies were employed to explore the associations between self-reported treatment qualities and six domains of HRQoL. Results In the sample, the geographical distribution were urban (5.70%), semi-urban (37.26%), and rural (57.03%). 67.30% of the participants were females. The mean age of the sample was 39.82 years (standard deviation = 9.76) ranging from 22 to 81 years. Multiple logistic regressions reported statistically significant associations of distance to ART facility with self-reported quality of services, advice, manners, and counseling, statistically significant association between self-reported manners quality and four domains of HRQoL, and statistically significant association between TASO membership and domains of HRQoL. Plots from regression anatomies reported that self-reported treatment qualities had statistically significant associations with six domains of HRQoL. Conclusions Treatment burden, self-reported treatment qualities, ART obtainment, and TASO were possible determinants of individual domains of HRQoL among PLWH in Uganda. PLWH’s HRQoL might be improved by promoting medical quality and optimizing ART obtainment in the healthcare providers’ practice. Findings in this study had important implications for the redesign of clinical guidelines, healthcare delivery, and health care co-ordination among PLWH globally.

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Section: Introductionmentioning

confidence: 99%

Associations between treatment burden, self-reported treatment qualities, antiretroviral therapy obtainment, and health-related quality of life among Ugandan PLWH

Guan

2023

Cost Eff Resour Alloc

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The role of socioeconomic and behavioral factors in HIV-related deaths

Dinçer,

Köse,

Ünal

2024

Humanit Soc Sci Commun

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Effects of Perceived Social Support on Health-Related Quality of Life in Asymptomatic and Symptomatic People Living with HIV in China: A Cross-Sectional Study

Xie

Wang

et al. 2023

CHR

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Objective: Improving health-related quality of life (HRQOL) in people living with HIV (PLWH) is one of the critical goals of HIV prevention and control in the following decades, and perceived social support (PSS) has always exhibited a positive influence on patients' HRQOL. This study aims to describe the gap in social support in improving HRQOL between symptomatic and asymptomatic PLWH. Methods: By analysing secondary data from an online survey, a multicenter, descriptive and crosssectional study was conducted. The correlation trend and differences between PSS and HRQOL among asymptomatic and symptomatic PLWH were determined. Results: Information from 493 PLWH with ART medication was finally analyzed: 34.89% asymptomatic PLWH and 65.11% symptomatic PLWH. There were significant differences observed between the two groups in terms of family income (χ2=9.782, p=0.021), HIV-positive duration (χ2=19.541, p＜0.001), stage of disease (χ2=9.617, p=0.008), and comorbidities (χ2=26.119, P＜ 0.001). The mean score of HRQOL of PLWH for the whole domain of the questionnaire was 86.56 (SD=15.95). In six domains of QOL and PSS, the asymptomatic group had better conditions than the symptomatic group. There was a linear association between PSS and HRQOL, not only in the symptomatic group but also asymptomatic population, after adjusting for potential confounding factors. When the level of PSS was between 60 and 80, the HRQOL of the symptomatic group was similar to that of the asymptomatic group. While the score of PSS exceeded 80, the HRQOL of the symptomatic group was less sensitive to the changes in PSS. The social and environmental status of HRQOL in PLWH was most strongly correlated with their PSS. Conclusion: The value of PSS on the HRQOL in PLWH is confirmed, especially for asymptomatic subjects. Healthcare providers need a complete understanding of the gap in social support between the asymptomatic and symptomatic populations. The comprehensive strategies, including symptom management, active treatment, and social support, should be more efficient for improving the overall health of symptomatic PLWH.

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Health-related quality of life and its association with sociodemographic, economic, health status and lifestyles among HIV-positive patients in northern Malaysia

Cited by 4 publications

References 13 publications

Associations between treatment burden, self-reported treatment qualities, antiretroviral therapy obtainment, and health-related quality of life among Ugandan PLWH

Associations between treatment burden, self-reported treatment qualities, antiretroviral therapy obtainment, and health-related quality of life among Ugandan PLWH

The role of socioeconomic and behavioral factors in HIV-related deaths

Effects of Perceived Social Support on Health-Related Quality of Life in Asymptomatic and Symptomatic People Living with HIV in China: A Cross-Sectional Study

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