Health-Related Quality of Life Assessment in Iranian Hemophilia Patients (Single Center); A Cross-Sectional Study

Abstract

Background: Hemophilia affects the patients′ life in many aspects. The major concerns are restriction on physical activities, life-threatening bleeding, arthropathy, etc., and worsening mental issues like anxiety. This study aimed to evaluate the health-related quality of life in hemophilia patients.Methods: In this cross-sectional study, 147 patients with hemophilia had been referred to special patients′ clinic at Kermanshah province (IRAN) for comprehensive medical care services. The patients who met the criteria of this study were selected using counting sampling method and were assessed with the quality of life in hemophilia patients′ questionnaire (A36 Hemofilia-QoL® questionnaire).Results: Out of 147 patients with hemophilia, 139 were male and 8 were female. The mean age of the subjects was 25.85±15.54 years. The results demonstrate that the total score of 65 patients (44.2%) had poor quality, 60 patients (40.8%) had moderate quality and 22 patients (15.0%) had good quality of life. Although there was no significant correlation between hemophilia A & B with health-related quality of life, there was a good connection between age, gender, level of education, and the severity of disease with health-related quality of life. Conclusion: According to the low quality of life in relation to health in hemophilia patients, different interventions should be administrated to increase health-related quality of life in these patients.

Prevalence of Depression in Hemophilia Patients: A Cross-Sectional Study

“…Hemophilia is an inherited X-linked bleeding disorder whose most common types are associated with a deficiency of coagulation factor VIII (hemophilia A) or factor IX (hemophilia B) (Golpayegani et al, 2021;Srivastava et al, 2013). Patients with hemophilia often face multiple complications, perceived risks, and functional limitations.…”