Health‐related quality of life during pregnancy: A repeated measures study of changes from the first trimester to birth

Morin, Mathieu; Claris, Olivier; Deroanne, Claude; Frelat, Alais; Place, Alice de; Molinier, Laurent; Matillon, Y.; Elhinger, Virginie; Vayssière, Christophe

doi:10.1111/aogs.13624

Cited by 23 publications

(22 citation statements)

References 23 publications

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“…All women in our study had a slight decrease in QOLS from the first to the second trimester ( Table 3). The decrease in quality of life among pregnant women has also previously been reported by Chang et al in Taiwan [42], Bai et al in the Netherlands [43], and Morin et al in France [44]. The observed decrease in quality of life is likely multifactorial, including both physical and emotional changes as the pregnancy proceeds.…”

Section: Discussionsupporting

confidence: 74%

“…Participants completed Q1 immediately after study enrollment in the first trimester and completed Q2 during the second trimester (13 weeks after enrollment). The timing of Q2 was based on prior studies on quality of life in pregnancy [27][28][29]. Women in the intervention group completed an additional satisfaction questionnaire after the consultation.…”

Section: Data Collectionmentioning

confidence: 99%

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The effect of a pharmacist consultation on pregnant women’s quality of life with a special focus on nausea and vomiting: an intervention study

Truong

Ngo

Ariansen

et al. 2020

BMC Pregnancy Childbirth

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Background Maternal wellbeing and quality of life (QOL) are increasingly being recognized as important for healthy pregnancies. The aim of this study was to investigate the impact of a pharmacist consultation on pregnant women’s QOL focusing on nausea and vomiting in pregnancy (NVP), and patient satisfaction. Methods For this intervention study in 14 community pharmacies, women in early pregnancy were recruited and assigned to a pharmacist consultation (intervention) or standard care (control). The consultation aimed to address each woman’s concerns regarding medications and pregnancy-related ailments. Data were collected through online questionnaires at baseline (Q1) and during the second trimester (Q2). The intervention group completed an additional satisfaction questionnaire after the consultation was completed. The primary outcome was the impact of the intervention on the Quality of Life Scale (QOLS) scores between the first and second trimesters. The impact of the intervention was assessed by linear regression, and secondary analyses were performed to assess effect modification by NVP. Results Of the 340 women enrolled in the study, we analyzed data for 245. Half (170/340) of the original participants were allocated to the intervention group, of whom 131 received the pharmacist consultation. Most women (75%, 78/96) reported that the consultation was useful to a large/very large extent. The consultation had no overall impact on QOLS scores between the first and the second trimesters compared with standard care (adjusted β: 0.7, 95% CI: -2.1, 3.4). The impact of the intervention on QOLS was greater amongst women with moderate/severe NVP (adjusted β: 3.6, 95% CI: -0.6, 7.7) compared to those with no/mild NVP (adjusted β: -1.4, 95% CI: -5.1, 2.2) (interaction term study group*NVP severity, p = 0.048). Conclusions The pregnant women highly appreciated the pharmacist consultation, but the intervention did not affect their QOL scores compared with standard care. Future studies should further explore the effect of a pharmacist consultation specifically for NVP and on other outcomes such as use of health care services and medication use in pregnancy. Trial registration Retrospectively registered in ClinicalTrials.gov (identifier: NCT04182750, registration date: December 2, 2019).

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Section: Discussionsupporting

confidence: 74%

Section: Data Collectionmentioning

confidence: 99%

The effect of a pharmacist consultation on pregnant women’s quality of life with a special focus on nausea and vomiting: an intervention study

Truong

Ngo

Ariansen

et al. 2020

BMC Pregnancy Childbirth

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“…In addition to this, factors that may affect QoL have also been studied. It was appropriate to use a generalised questionnaire to determine the subject's health-related quality of life (HRQoL) values [33][34][35][36], given that most pregnant women do not have a fatal illness [37]. As one of the most common means for assessing the overall health of the body, EQ-5D is a powerful generic tool, particularly in regards to evaluating symptoms of pain and anxiety/depression [38].…”

Section: Discussionmentioning

confidence: 99%

The impact of lower urinary tract symptoms on the quality of life during pregnancy: a cross-sectional study from Palestine

et al. 2020

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Background Lower urinary tract symptoms (LUTS) are prevalent among pregnant women. Several articles show the impact of LUTS on pregnant women’s quality of life (QoL). This study was designed to examine the impact of non-pathological LUTS on QoL among pregnant Palestinian women. Methods A cross-sectional, hospital-based study was conducted on women who were pregnant and receiving regular antenatal care at the obstetrics and gynecology clinic in Rafidia Hospital, Palestine. This self-administered questionnaire included the Urinary Distress Inventory – short-form (UDI-6), the Incontinence Impact Questionnaire – short-form (IIQ-7), the European Quality of Life scale – 5 dimensions (EQ-5D), and the European Quality of Life – visual analogue scale (EQ-VAS). A convenience sampling method was used. In addition to this, multiple linear regression analyses were performed aiming to identify variables that have a significant relationship with QoL (i.e. socio-demographic variables, UDI-6 score, and IIQ-7 score). Results This study included a total of 306 pregnant women. Participants had a mean age of 26.9 years (SD, 3.6). The subjects scored an average of 31.2 ± 19.2 out of 100 points for the UDI-6 scale and an average of 31.9 ± 24.9 out of 100 points for the IIQ-7 scale. On the other hand, the subjects’ average EQ-5D and EQ-VAS scores were 0.76 ± 0.17 and 67.96 ± 19.28 respectively. The subjects’ responses on UDI-6 significantly correlated with their responses on both the EQ-5D and EQ-VAS scales (r = − 0.338, p < 0.001 and r = − 0.206, p < 0.001, respectively). Likewise, their responses on IIQ-7 also significantly correlated with their responses on both the EQ-5D and EQ-VAS scales (r = − 0.389, p < 0.001 and r = − 0.329, p < 0.001, respectively). Regression analysis found that the UDI-6 score (p = 0.001) and IIQ-7 score (p < 0.001), were significantly and negatively associated with EQ-5D index scores. Conclusions Our study shows a remarkable correlation between LUTS and QoL among pregnant women. Further longitudinal studies are required to assess the status of LUTS in the pre-pregnancy stage to ascertain a more accurate assessment of LUTS or LUTS related intervention and its impact on QoL during pregnancy.

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“…Pregnancy is not a pathological condition [ 5 ], it involves anatomical, physiological, and biochemical changes in the woman’s body [ 5 ]. It is known that the quality of life decreases significantly overtime during pregnancy and it is even worse in the case of pathological pregnancy [ 6 ]. Pregnancy is associated with depression and other psychosomatic conditions [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Dry eye, its clinical subtypes and associated factors in healthy pregnancy: A cross-sectional study

Asiedu¹,

Kyei

Adanusa

et al. 2021

PLoS ONE

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The study determined the frequency of dry eye, its clinical subtypes and risk factors among pregnant women. This study was a hospital-based cross-sectional study of pregnant women visiting the antenatal clinic of the University of Cape Coast hospital. Clinical dry eye tests were performed along with the administration of a symptom questionnaire. Frequencies, chi-square analysis and logistic regression analyses were conducted to determine the frequency of dry eye disease, its clinical subtypes and associated factors. The prevalence of dry eye disease among the cohort of pregnant women was 82/201 (40.8% 95% confidence interval 34.3%-47.3%). Among the 82 pregnant women with dry eye disease, the frequencies of the clinical subtypes of dry eye were: evaporative dry eye [15/82(18.3%; 95% CI, 12.2%–25.2%)], aqueous deficient dry eye [10/82(12.2.%; 95% CI, 7.3%–18.3)], mixed dry eye [6/82(7.3%; 95% CI, 3.7%–11.0%)], and unclassified dry eye [51/82(62.2%; 95% CI, 52.4%–72.0%)]. Binary logistic regression analysis showed that the following factors were not significantly associated with dry eye: age, BMI, lipid profile, prolactin level, testosterone level, ocular protection index and blink rate. Only gestational age was significantly associated with dry eye disease in pregnancy. In conclusion, the current study showed that dry eye disease occurs frequently in pregnant women ranging from the first to the third trimester and it is associated with increasing gestational age. The evaporative dry eye was more common compared to the aqueous deficient dry eye, but most dry eye could not be classified.

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Health‐related quality of life during pregnancy: A repeated measures study of changes from the first trimester to birth

Cited by 23 publications

References 23 publications

The effect of a pharmacist consultation on pregnant women’s quality of life with a special focus on nausea and vomiting: an intervention study

The effect of a pharmacist consultation on pregnant women’s quality of life with a special focus on nausea and vomiting: an intervention study

The impact of lower urinary tract symptoms on the quality of life during pregnancy: a cross-sectional study from Palestine

Dry eye, its clinical subtypes and associated factors in healthy pregnancy: A cross-sectional study

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