Health-Related Quality of Life in Hemodialysis Patients: An Iranian Multi-Center Study

Abstract

BackgroundThe effectiveness of health care and health policy developments are often determined by health-related quality of life (HRQOL) assessment.ObjectivesThe objective of this study was to explore the potential corresponding factors and traditional biomarkers of HRQOL in a large number of Iranian hemodialysis patients.Patients and MethodsA total of 6,930 chronic hemodialysis (HD) patients enrolled. KDCS-SF version 1.3 questionnaire was used to assess the health related quality of life (HRQOL). We pooled PCS, MCS and KDCS scores with random effect model from 19 similar studies performed between 1996 and 2010ResultsThe mean age was 54.4 ± 17.1 years. Mean PCS, MCS and KDCS scores obtained for the study cohort were 40.79 ± 20.10, 47.79 ± 18.31 and 57.97 ± 11.70, respectively; the total score of SF-36 plus KDCS was 51.12 ± 13.41 as well. The most common primary known disease was hypertension (31.9%) and the second etiology was diabetes (25.5%). In multilevel logistic regression, Kt/V between 1 and 1.2 and PCS, KDCS more than 50 were considered as a significant reduction in the risk of hospitalization.ConclusionsThis study showed that PCS and MCS score were slightly more than overall results while KDCS was slightly less than overall results. In addition, dialysis adequacy with Kt/V between 1 and 1.2 is associated with lower rate of hospitalization.

Depression, anxiety and health‐related quality of life amongst patients who are starting dialysis treatment

“…Numerous studies have reported that HRQL is significantly affected in patients with CKD (Soni et al ; Untas et al ; Avramovic & Stefanovic ; Pagels et al ; Rostami et al ). On comparing the results obtained in our patients with those for a healthy reference population, according to the Spanish version of the SF‐36 questionnaire, we find that our scores were lower for all the general dimensions of the KDQOL‐SF, with a difference of the means ranging from 52.53 for the physical role to 4.09 for social support.…”

Gender effect on quality of life in hemodialysis patients

“…In this study, females had poor self-reported health-related quality of life (HRQoL), but better survival than men [1]. We have also found a lower quality of life (QoL) score in women among 6,930 HD patients [2].…”

Comparison in Pattern of Quality of Life in Different Regions

“…Physical and Mental component summary scores in Iranian HD patients were 40.79 and 47.79 respectively [2]. Moreover, these parameters were different in American HD patients (34.4-37.7 and 41.73-41.7 respectively) [3] and Netherlands HD patients (38.8 and 43.7 respectively) [4].…”

“…The different ethnic groups may be another reason. For example, the prevalence of endstage renal disease (ESRD) and some risk factors of chronic kidney disease (CKD) such as hypertension and diabetes are widely different among various ethnic groups [2]. Age of participants, sample size and level of education which are different among countries are other important confounding factors.…”

“…We have also investigated health related quality of life among Iranian HD patients [2]. Physical and Mental component summary scores in Iranian HD patients were 40.79 and 47.79 respectively [2].…”