Health-Related Quality-of-Life in a cohort undergoing cholecystectomy

Abstract

IntroductionPatient-related outcome measures are crucial when assessing outcome from surgical intervention registers. The aim of this study was to analyse what factors affect Health-Related Quality of Life (HRQoL) in patients undergoing cholecystectomy, and to assess the feasibility of SF-36 as a HRQoL instrument in a patient register.MethodsThe SF-36 questionnaire was distributed to patients preoperatively and 6–9 months after surgery. The outcome of patients who had undergone planned surgery between January 1, 2010 and June 30, 2011 at six units, with response rates of at least 100 per year, formed the basis for the present study. Expected outcome from a background population was determined from a Swedish cohort assembled previously.ResultsAltogether 919 patients (646 women, 273 men) at the six units answered the questionnaire. Mean age was 52 years, standard deviation 15 years. Preoperatively, the surgery cohort rated lower on all subscales of the SF-36 than the age- and gender-matched background population. Postoperatively, they did not rate lower in any of the subscales. High age was associated with a significantly lower increase in bodily pain and Physical Component Summary (both p < 0.05). Open surgery was associated with a significantly lower increase in the Physical Component Summary (p < 0.05).DiscussionRegardless of indication for surgery, high age is associated with less benefit from surgery according to this questionnaire study. SF-36 is appropriate for measuring the impact of gallstone surgery on HRQoL.

Quality of life and psychological and gastrointestinal symptoms after cholecystectomy: a population-based cohort study

“… 1 There are some limited and inconsistent information available about the long-term quality of life in these patients. 2 In previous studies, female gender and cholecystectomy for gallstone colic correlated with low quality of life scores. Female gender also correlated with a higher risk of pain in the right upper stomach quadrant after cholecystectomy.…”

“…There are some limited and inconsistent information available about the long-term quality of life in these patients 2. In previous studies, female gender and cholecystectomy for gallstone colic correlated with low quality of life scores.…”

Quality-of-life After Cholecystectomy in Kazakhstan and Sweden: Comparative Study Based on the Gastrointestinal Quality-of-life Index Questionnaire

“…Furthermore, the surgical technique has developed during this period, which may also have biased the outcome. The SF-36 instrument is routinely used for assessing quality of life in patients undergoing gallstone surgery in the Swedish national register for gallstone surgery [25], [26]. Since the start of GallRiks 2005, the perceived QoL measured with SF-36 has remained relatively stable [25].…”

Long-term patient-reported outcomes following laparoscopic cholecystectomy

“…This positive result following cholecystectomy is consistent with previous published literature. [ 11 , 12 , 24 , 31 ] In the case of severe complication such as BDI, several studies reported that extremely long-term follow-up of 8 to 12 years was needed to improve QoL after cholecystectomy. [ 14 , 32 , 33 ] Also, other studies suggested that the occurrence of a BDI has a great impact on the patient's physical and mental QoL even after excellent functional outcome following repair.…”

“…[ 22 ] However, there is limited and inconsistent information available about PRO in these patients. [ 23 , 24 ] For these reasons, the clinical management of these patients is frequently without an evidence-based approach. The purpose of this prospective multicenter observational study is to analyze which factors have the greatest impact on short- and long-term PRO including various postoperative symptoms and QoL using the GIQLI questionnaire following cholecystectomy.…”