Health-related quality of life in men receiving prostate brachytherapy on RTOG 98-05

Feigenberg, Steven J.; Lee, W. Robert; DeSilvio, Michelle; Winter, P. Kathryn; Pisansky, Thomas M.; Bruner, Deborah Watkins; Lawton, Colleen A.; Morton, G.; Baikadi, Madhava; Sandler, Howard M.

doi:10.1016/j.ijrobp.2004.12.061

Cited by 57 publications

(39 citation statements)

References 29 publications

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“…Subsequent studies have also confirmed that the FACT-P is able to detect significant changes in QoL. 16,17,19 In our own study we found that the FACT-P values did not significantly change in patients in whom the PS deteriorated. In contrast there were significant changes in SEIQoL-DW and VAS scores.…”

Section: Quality Of Life In Prostate Cancersupporting

confidence: 66%

“…5,15 Previous studies have used the FACT-P to evaluate QoL in patients with prostate cancer undergoing external beam radiotherapy, 16 brachytherapy, 16,17 surgery, 16 cryosurgery, 18,19 chemotherapy 20 and treatment with an epidermal growth factor receptor inhibitor. 21 These studies have reported significant changes in health-related QoL in response to the various anti-cancer treatments.…”

Section: Quality Of Life In Prostate Cancermentioning

confidence: 99%

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Measuring the individual quality of life of patients with prostate cancer

Stone

Matar

et al. 2008

Prostate Cancer Prostatic Dis

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Prostate cancer can have diverse effects on patients' quality of life (QoL). Standard QoL questionnaires do not address all of the concerns expressed by such patients. The primary purpose of this study was to identify those issues with the greatest influence on the QoL of patients with prostate cancer. A secondary aim was to compare the performance of the Schedule for the Evaluation of Individual Quality of Life-Direct Weighting (SEIQoL-DW) semi-structured interview with the Functional Assessment of Cancer Therapy-Prostate questionnaire (FACT-P). A mixed population of patients with prostate cancer (including those with localized and metastatic disease) completed the SEIQoL-DW and the FACT-P. The SEIQoL-DW was satisfactorily completed by 180 patients, including 93 patients with metastatic disease. Patients identified 144 separate QoL concerns, and these were then independently grouped by three of the authors into 13 distinct themes. The most frequently identified themes were 'leisure and hobbies', 'family' and 'health'. The themes that patients considered to be the most important were 'partner/spouse', 'family' and 'health'. Patients were most satisfied with their QoL in the domains of 'family', 'partner/spouse' and 'friends'. They were least satisfied with 'sexuality', 'mobility' and 'psychological factors'. Patients with metastatic disease rated their QoL significantly (Po0.0001) lower than other patients using the FACT-P, but not using the SEIQoL-DW (P ¼ 0.07). Patients with prostate cancer identified numerous QoL concerns that are not included (or are underrepresented) in standard health-related QoL questionnaires such as the FACT-P. Health-related QoL questionnaires may underestimate the QoL of patients with metastatic disease.

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Section: Quality Of Life In Prostate Cancersupporting

confidence: 66%

Section: Quality Of Life In Prostate Cancermentioning

confidence: 99%

Measuring the individual quality of life of patients with prostate cancer

Stone

Matar

et al. 2008

Prostate Cancer Prostatic Dis

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“…(1-35%) 12-59% (o1 to 14%) 3-15% (o1 to 24%) 4,6,7,[9][10][11][12][13][14]16,23,24,27,34,37,46,53,[55][56][57][58]60,63,65,66,[69][70][71]73,74 Single surgeon case series 2 24-69% …”

Section: -67%mentioning

confidence: 99%

Estimating the risk of long-term erectile, urinary and bowel symptoms resulting from prostate cancer treatment

Bhatnagar

Stewart

Huynh

et al. 2006

Prostate Cancer Prostatic Dis

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Reports on long-term complications resulting from treatment for localized prostate cancer are very inconsistent. In order to estimate the risks of long-term erectile dysfunction, urine symptoms and bowel symptoms following prostatectomy (RP), external conventional or conformal beam radiation (ERT or CRT) and brachytherapy (BRT), 98 papers from the PubMed and Cochrane Clinical Trial databases were selected, reviewed and critically evaluated. The majority of papers were institutionbased retrospective and prospective follow-up studies; only two of these studies measured the risk of developing more than one treatment complication. Due to differences in study designs and populations, it is difficult to directly compare studies and not meaningful to calculate summary estimates. In addition to focusing on randomized clinical trials and well-designed population based studies, future research should adopt standardized methodologies and should measure the risk of developing more than one treatment complication.

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“…Многочисленные клинические исследования доказали безопасность и эф фективность брахитерапии [7,8], в том числе радиацион ной онкологической группой (RTOG) [9,10].…”

Section: Discussionunclassified

“…[8][9][10][11]. Согласно данному анализу ни один из пере численных факторов не оказывал достоверного влияния на результаты лечения.…”

Section: результатыunclassified