Health‐related quality of life in 794 patients with a peripheral facial palsy using the Fa<scp>CE</scp> Scale: a retrospective cohort study

Kleiss, Ingrid J.; Hohman, Marc H.; Susarla, Srinivas M.; Marres, H.A.M.; Hadlock, Tessa A.

doi:10.1111/coa.12434

Cited by 86 publications

(109 citation statements)

References 34 publications

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“…The most commonly raised concerns centred on eye function, with 12 participants mentioning a total of 27 problems. This is not surprising as previous studies have shown a similar result . In our study, participants cited an inability to blink, excessive dryness, visual impairment and the need to tape their affected eye shut at night as major problems in their day‐to‐day life.…”

Section: Discussionsupporting

confidence: 83%

Development of the Alberta facial clinical evaluation scale: A patient‐centred outcomes instrument for facial nerve paralysis

Hamour

Mendez

Biron

et al. 2019

Clinical Otolaryngology

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Objectives Facial nerve paralysis has functional, psychological and social consequences for patients. Traditionally, outcome measurements for facial nerve injuries have been clinician derived. Recent literature has shown that patient perspective is valuable and necessary in outcomes research. This study aimed to identify patient domains of concern and subsequently, develop a point‐of‐care questionnaire for clinical use. Design This mixed‐methods prospective study was completed in three phases. In Phase I, 15 facial nerve injury patients were interviewed individually. Interviews were digitally recorded, transcribed and coded with NVivo software. Analysis led to a conceptual framework detailing the most important quality of life outcomes. During Phase II, a focus group was held with five new patients in order to prioritise the outcome themes to a top six list. A second focus group was held with Otolaryngology‐Head and Neck staff surgeons to create a 25‐item questionnaire based on these six themes. In Phase III, the questionnaire was administered to 10 new patients to test for comprehension. Setting University of Alberta Hospital, Edmonton, Alberta, Canada. Participants A total of 30 patients with facial nerve injury were included in the various phases in the study. In addition, 5 staff Otolaryngology‐Head and Neck surgeons participated as focus group contributors. Main outcome measures Domains of concern and quality of life outcomes as reported by facial nerve injury patients. Results Patients identified a total of 16 themes encompassing both functional and psychological deficits related to their facial nerve injury. From these findings, a 25‐item Likert‐type scale, the A‐FaCE scale, was developed for clinical use. Conclusions Patients with facial nerve paralysis experience functional and psychological deficits. This study led to the creation of the first patient‐reported instrument for this population that addresses functional impairment, social function, psychological well‐being and self‐perception of appearance.

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Section: Discussionsupporting

confidence: 83%

Development of the Alberta facial clinical evaluation scale: A patient‐centred outcomes instrument for facial nerve paralysis

Hamour

Mendez

Biron

et al. 2019

Clinical Otolaryngology

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“…There is relatively scant published information about FP disability as it relates to etiology. Most authors who studied it found that etiology was not a predicting factor of PROMs . One previous study compared the morbidity of facial nerve dysfunction arising from surgical intervention for VS (n = 53) with those resulting from Bell palsy (n = 22).…”

Section: Discussionmentioning

confidence: 99%

Facial Palsy‐Specific Quality of Life in 920 Patients: Correlation With Clinician‐Graded Severity and Predicting Factors

et al. 2018

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“…20,21,38,39 In 2 cross-sectional studies assessing QOL in patients with acoustic neuroma, Ryzenman et al 21 found that 28% of patients were significantly affected by facial weakness, and Lee et al 38 found a significantly lower QOL scores in patients with facial paralysis compared with normal patients. Looking at patients with all-cause facial paralysis at initial presentation, Kleiss et al 20 found that patients with facial paralysis have a mean (SD) baseline Facial Clinimetric Evaluation score of 47.3 (19.2) representing health-related QOL on a scale of 0 to 100. Our study expands on these findings by comparing QOL scores between patients with all-cause facial paralysis and control patients and presenting a model showing that QOL scores are significantly affected by facial paralysis.…”

Section: Discussionmentioning

confidence: 99%

Association Among Facial Paralysis, Depression, and Quality of Life in Facial Plastic Surgery Patients

Nellis

Ishii

Byrne

et al. 2017

JAMA Facial Plast Surg

169

127

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IMPORTANCE Though anecdotally linked, few studies have investigated the impact of facial paralysis on depression and quality of life (QOL).OBJECTIVE To measure the association between depression, QOL, and facial paralysis in patients seeking treatment at a facial plastic surgery clinic.DESIGN, SETTING, PARTICIPANTS Data were prospectively collected for patients with all-cause facial paralysis and control patients initially presenting to a facial plastic surgery clinic from 2013 to 2015. The control group included a heterogeneous patient population presenting to facial plastic surgery clinic for evaluation. Patients who had prior facial reanimation surgery or missing demographic and psychometric data were excluded from analysis.MAIN OUTCOMES AND MEASURES Demographics, facial paralysis etiology, facial paralysis severity (graded on the House-Brackmann scale), Beck depression inventory, and QOL scores in both groups were examined. Potential confounders, including self-reported attractiveness and mood, were collected and analyzed. Self-reported scores were measured using a 0 to 100 visual analog scale. RESULTSThere was a total of 263 patients (mean age, 48.8 years; 66.9% were female) were analyzed. There were 175 control patients and 88 patients with facial paralysis. Sex distributions were not significantly different between the facial paralysis and control groups. Patients with facial paralysis had significantly higher depression, lower self-reported attractiveness, lower mood, and lower QOL scores. Overall, 37 patients with facial paralysis (42.1%) screened positive for depression, with the greatest likelihood in patients with House-Brackmann grade 3 or greater (odds ratio, 10.8; 95% CI, 5.13-22.75) compared with 13 control patients (8.1%) (P < .001). In multivariate regression, facial paralysis and female sex were significantly associated with higher depression scores (constant, 2.08 [95% CI, 0.77-3.39]; facial paralysis effect, 5. 98 [95% CI,]; female effect, 1.95 [95% CI, 0.65-3.25]). Facial paralysis was associated with lower QOL scores (constant, 81.62 [95% CI,]; facial paralysis effect, −16.06 [95% CI,).CONCLUSIONS AND RELEVANCE For treatment-seeking patients, facial paralysis was significantly associated with increased depression and worse QOL scores. In addition, female sex was significantly associated with increased depression scores. Moreover, patients with a greater severity of facial paralysis were more likely to screen positive for depression. Clinicians initially evaluating patients should consider the psychological impact of facial paralysis to optimize care.LEVEL OF EVIDENCE 2.

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Health‐related quality of life in 794 patients with a peripheral facial palsy using the FaCE Scale: a retrospective cohort study

Cited by 86 publications

References 34 publications

Development of the Alberta facial clinical evaluation scale: A patient‐centred outcomes instrument for facial nerve paralysis

Development of the Alberta facial clinical evaluation scale: A patient‐centred outcomes instrument for facial nerve paralysis

Facial Palsy‐Specific Quality of Life in 920 Patients: Correlation With Clinician‐Graded Severity and Predicting Factors

Association Among Facial Paralysis, Depression, and Quality of Life in Facial Plastic Surgery Patients

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