Health-Related Quality of life of Complete versus Infarct artery-only Percutaneous Coronary Revascularization in Multi-vessel Disease with ST-Segment Elevation Myocardial Infarction

Abstract

Objective: The aim of this study was to evaluate the health-related quality of life (HRQoL) as measured by the EQ-5D (European quality of life-5 dimensions) self-report questionnaire in patients treated with complete revascularization versus infarct artery-only revascularization at index admission. Background: The revascularization strategies for multivessel disease while undergoing primary percutaneous coronary intervention (P-PCI) on HRQoL is uncertain. Methods and Results: STEMI patients with multivessel disease underwent either complete or between April 1, 2012, and March 31, 2014, were subdivided into those who underwent complete revascularization (n = 133) or infarct-related artery (IRA)-only revascularization (n = 139) at index admission. The EQ-5D assessed mobility, self-care, usual activity, pain or discomfort, and anxiety or depression. Patient groups were differed at baseline by gender and prevalence of heart failure. At 2-year follow-up, both mean (±SD) EQ-VAS and EQ-5D utility scores were lower for patients who underwent complete revascularization versus infarct artery-only revascularization (60.00 (±18.8) vs. 59.03 (±16.9), P < 0.03, and 0.68 (±0.02) vs. 0.54 (±0.02), P<0.004, respectively). Conclusion: The clinically significant improvement in QoL was seen in the complete revascularization group compared with treating only the IRA at 24 months.