Health‐related quality of life of Brazilian children and adolescents with benign and malignant solid tumours: A prospective cohort study during the first year after hospital admission

Abstract

Introduction This study aims to assess the impact of paediatric benign and malignant solid tumours and its treatment on the health‐related quality of life of children and adolescents who were followed up in a Reference Center in Pediatric Oncology in Rio de Janeiro. Methods It is a prospective cohort study. Quality of life assessment was performed using the PedsQL™ 4.0 Generic Core Scales and PedsQL™ 3.0 Cancer Module protocols three times: during hospital admission (T1), 6 months after admission (T2) and 1 year after admission (T3). Results We evaluated 132 patients, 59 men and 73 women, aged 2–17 years. In PedsQL™4.0, the Emotional Functioning scale was the one with the worst scores, while the scores on the Social Functioning scale was the best. In PedsQL™ 3.0, the worst domains were Procedural Anxiety and Worry. Patients with malignant bone tumours had the worst health‐related quality of life. The group who received only surgery had better results. Total scores of PedsQL™4.0 and PedsQL™ 3.0 improved between T1 and T3. Conclusion Children and adolescents with malignant and benign neoplasms undergo changes in quality of life as a result of the disease and treatment, but an improvement has been observed over time.

Prevalence of Anxiety, Depression, and Post-Traumatic Stress Disorder among Children and Adolescents with Cancer: A Systematic Review and Meta-Analysis

“…A total of 16 studies were conducted in North America, of which the majority were performed in the USA (Bemis et al, 2015; Cousino et al, 2017; Cox et al, 2019; Dupuis et al, 2016; Foster et al, 2020; Germann et al, 2015; Hinds et al, 2013; Hockenberry et al, 2017; Karimi et al, 2020; Kunin-Batson et al, 2016; Liu et al, 2018; Myers et al, 2014; Okado et al, 2018; Rodgers et al, 2019; Stoppelbein et al, 2006) and only one study was conducted in Canada (Lazor et al, 2019). Two studies were conducted in South America in Brazil (Coça et al, 2019; Scarpelli et al, 2008). There are 12 studies conducted in Asia, of which three studies in Japan(Sato et al, 2014; Tsuji et al, 2011; Wakimizu et al, 2011), three studies in Taiwan (Tsai et al, 2013; Wu et al, 2013, 2016), two studies in China (Li et al, 2010, 2013b), two studies in South Korea (Kim & Yi, 2013; Sohn et al, 2017), one in Indonesia (Sitaresmi et al, 2008) and one in Iran (Zahed & Koohi, 2020).…”

“…There are six instruments used to measure anxiety alone and six tools measured both anxiety and depression, while one assessed all three psychological disorders at once. Among the 26 studies measuring anxiety, the PedsQL tool, a modular instrument assessing health-related quality of life in children which incorporates different subscales to differentiate between treatment and procedural anxiety, was most commonly used (Canning et al, 2014; Coça et al, 2019; Dupuis et al, 2016; Lazor et al, 2019; Sato et al, 2014; Scarpelli et al, 2008; Sitaresmi et al, 2008; Tsuji et al, 2011). However, none of the above studies presented a prevalence rate that could be pooled in the meta-analysis.…”

Avaliação da qualidade de vida de adolescentes em tratamento de câncer: Uma revisão integrativa

“…A maior parte dos estudos incluídos (N = 07) utilizou a quimioterapia como forma de tratamento do câncer. Coça et al (2019) e Skaczkowski (2018) compararam a quimioterapia com outras formas de tratamento, sendo observado que os pacientes em tratamento com quimioterapia apresentam os piores escores de QV nos domínios de saúde física, funcionamento emocional, social e escolar quando comparada a qualquer outra forma de tratamento.…”

The effects of administered interventions on quality of life of children with cancer in Turkey: A systematic review and meta‐analysis

“…All such symptoms impair the quality of life among affected children physically, psychologically, and intellectually (Fazelniya et al, 2017; Yağcı Küpeli et al, 2012). Studies report that children's quality of life decreases once they are diagnosed with cancer and they start cancer treatment (Byrne et al, 2018; Coça et al, 2019; Fazelniya et al, 2017; Müller et al, 2016).…”