Health-related quality of life on combination therapy with peritoneal dialysis and hemodialysis in comparison with hemodialysis and peritoneal dialysis: A cross-sectional study

Tanaka, Mototsugu; Ishibashi, Yoshitaka; Hamasaki, Yoshifumi; Kamijo, Yuka; Idei, Mayumi; Kawahara, Takuya; Nishi, Takahiro; Takeda, Michio; Nonaka, Hiroshi; Nangaku, Masaomi; Mise, Naobumi

doi:10.1177/0896860819894066

Cited by 17 publications

(20 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In 2008, differences in QOL were compared between 77 in-center HD and 58 CAPD/PD patients, and the study concluded that patients on HD experienced more compromised QOL compared to those on CAPD/PD [12]. e same results were supported later by more recent trials [13][14][15]. However, some other trials concluded that depression is highly more prevalent in patients on PD than in those on HD [16].…”

Section: Discussionmentioning

confidence: 98%

Prevalence of Depression and Sleep Disorders in Patients on Dialysis: A Cross-Sectional Study in Qatar

Al-Ali

Elshirbeny

Hamad

et al. 2021

International Journal of Nephrology

View full text Add to dashboard Cite

Patients with end-stage renal disease treated with dialysis have poor quality of life (QOL). Improving QOL in these patients with multiple comorbidities is a large challenge. We performed a cross-sectional study to evaluate the prevalence and associated factors of depression and sleep disorders in this population. Our primary aim was to evaluate QOL measures in dialysis patients in Qatar through a series of validated questionnaires mainly concerning depression and sleep disorders. Our secondary aim was to study the associations of age, sex, and comorbid conditions with the QOL measures. We hypothesized that end-stage renal disease (ESRD) patients on dialysis would have disturbed QOL due to both ESRD and dialysis and comorbidities. This prospective cross-sectional study included adult ESRD patients receiving either hemodialysis (HD) or peritoneal dialysis (PD) in the main tertiary dialysis unit in Qatar. We administered two surveys to evaluate depression (the Center for Epidemiologic Studies Depression Scale, http://www.bmedreport.com/archives/7139) and sleep disorders (the Pittsburgh Sleep Quality Index, https://www.sleep.pitt.edu/instruments/). We also reviewed patient demographics, comorbidities, and laboratory test results to evaluate any associated factors. We randomly studied 253 patients (62% on HD and 38% on PD). Overall, 48% of patients had depression, while 83.8% had sleep disorders. The PD had more poor sleepers than the HD group (89.1% versus (vs.) 75%, p = 0.003 ). Most of our dialysis patients had poor sleep, but it was more significant in the elderly group 109 (90%) than in the young group 103 (78%) ( p = 0.009 ). Patients with diabetes mellitus (DM) had significantly more prevalence of poor sleep (131 (88.5%)) than those without DM (81 (77.1%), p = 0.01 ). More female patients had depression than male patients (52% vs. 25%, p < 0.0001 ; odds ratio: 3.27 (95% confidence interval: 1.9–5.6), p < 0.0001 ). This is the first study in Qatar to evaluate depression and sleep disorders in patients on dialysis therapy.

show abstract

Section: Discussionmentioning

confidence: 98%

Prevalence of Depression and Sleep Disorders in Patients on Dialysis: A Cross-Sectional Study in Qatar

Al-Ali

Elshirbeny

Hamad

et al. 2021

International Journal of Nephrology

View full text Add to dashboard Cite

show abstract

“…Recently, we reported that PDþHD may have a similar profile of health-related quality of life to PD and have an advantage in role and social participation as compared with HD. 27 PD and HD combination may be an individualized dialysis modality and a treatment of choice in patients with ESRD with decreased RKF who prefer PD lifestyles for social, economic, or geographic reasons.…”

Section: Discussionmentioning

confidence: 99%

“…Forty-two PDþHD patients were matched with 42 HD patients with 1:1 matching for age and diabetic nephropathy among the entire cohort (Figure 1), in which we previously investigated health-related quality of life among PDþHD, HD, and PD patients. 27 The exclusion criteria of the study were as follows: patients younger than 20 years; those who changed their dialysis modality or were hospitalized within 1 month; those without a decision-making ability due to cognitive impairment; those with severe frailty or a life expectancy of less than 6 months. PDþHD patients receiving 2 or more HD sessions per week and HD patients receiving other than 3 HD sessions per week were also excluded.…”

Section: Patientsmentioning

confidence: 99%

Hospitalization for Patients on Combination Therapy With Peritoneal Dialysis and Hemodialysis Compared With Hemodialysis

Tanaka

Ishibashi

Hamasaki

et al. 2020

Kidney International Reports

Self Cite

View full text Add to dashboard Cite

Introduction: Combination therapy with peritoneal dialysis and hemodialysis (PDþHD) is widely used for PD patients with decreased residual kidney function in Japan; however, hospitalization for this combined dialysis has not been investigated so far. We compared the risk of hospitalization for PDþHD with that for HD. Methods: A multicenter, prospective observational study was conducted on 42 PDþHD and 42 HD patients matched for age and diabetic nephropathy. The main outcome measure was the cumulative incidence of hospitalization for any cause assessed with the Kaplan-Meier method. Hospitalization rates (the number of admissions per 100 patient-years) associated with dialysis modality were also calculated. The impact of dialysis modality on time to hospitalization was analyzed using the Cox proportional hazard model.Results: There was no significant difference between groups in terms of age, sex, dialysis vintage, diabetic nephropathy, and comorbidities. The cumulative incidence of hospitalization did not significantly differ between the groups (log-rank test, P ¼ 0.36). Although total hospitalization rates were 66.0 in PDþHD and 59.2 in HD, hospitalization rates for the sum of PD-related infections (a composite of catheter-related infection and peritonitis) and vascular access troubles were 21.7 in PDþHD and 7.2 in HD. On univariate Cox proportional hazard analysis, dialysis modality had no significant impact on time to hospitalization. Conclusion:The risk of hospitalization was not significantly different between PDþHD and HD, although PDþHD patients had a higher risk of dialysis access-related complications than HD patients.

show abstract

“…PD+HD had a close profile of the health-related quality of life of PD, which was better than HD especially in role and social domains. 15 Fluid status of PD+HD was also relatively good as compared with that of HD and PD. 25 Furthermore, totalhospitalization risk was similar between PD+HD and HD, although PD+HD may have a higher hospitalization risk of dialysis access-related complications than HD.…”

Section: Discussionmentioning

confidence: 91%

Ultrafiltration volume by once‐weekly hemodialysis is a predictor of technique survival of combination therapy with peritoneal dialysis and hemodialysis

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

Health-related quality of life on combination therapy with peritoneal dialysis and hemodialysis in comparison with hemodialysis and peritoneal dialysis: A cross-sectional study

Cited by 17 publications

References 40 publications

Prevalence of Depression and Sleep Disorders in Patients on Dialysis: A Cross-Sectional Study in Qatar

Prevalence of Depression and Sleep Disorders in Patients on Dialysis: A Cross-Sectional Study in Qatar

Hospitalization for Patients on Combination Therapy With Peritoneal Dialysis and Hemodialysis Compared With Hemodialysis

Ultrafiltration volume by once‐weekly hemodialysis is a predictor of technique survival of combination therapy with peritoneal dialysis and hemodialysis

Contact Info

Product

Resources

About