Health Related Quality of Life, Anxiety and Depression among Tuberculosis Patients in Kathmandu, Nepal

Abstract

Background and Objectives: Tuberculosis remains one of the major public health problems in Nepal. This study was carried out to assess the Health related Quality of life and Anxiety- Depression level of Tuberculosis patients in Kathmandu.Material and Methods: A cross-sectional study was conducted at Urban Direct Observation Treatment Short Course center using 150 study populations. Questionnaires containing socio-demographic characteristics, Self Reporting Questionnaire, Short Forms Health Survey, Hamilton Anxiety Rating Scale, and Hamilton Depression Rating Scale. SPSS 20, SF-36 Scoring Software were used for data management.Results: Majority of respondents (57.3%) were male, age group of 21-25 years. Majority of respondents suffered from Extra Pulmonary Tuberculosis, gland TB was in higher prevalence (31.3%). Most of the respondents found to poor HRQoL score where only 1.4% female and 1.7% male’s had above average HRQoL. There was no correlation between anxiety, depression, Mental Component Summary and Physical Component Summary score in pulmonary Tuberculosis patients unlike Extra pulmonary Tuberculosis patients, where there was strong correlation between anxiety and depression (r=0.721, p=0.000). There was negative correlation between PCS and MCS (r= -0.232, p= 0.037). There was no association between gender and PCS score on both types of TB patients. At majority of domain of HRQoL male had higher score than female.Conclusion: Co-morbidities of anxiety and depression in tuberculosis patients impact on health-related quality of life.Janaki Medical College Journal of Medical Sciences (2016) Vol. 4 (1): 13-18

Depression among TB patients and associated factors in Kathmandu Valley, Nepal

“…The prevalence of depression in our study was lower than findings from two other studies conducted in Nepal. In the first study among an urban sample patient with TB or MDR-TB, 18% suffered from some levels of depression requiring medical attention (Devkota et al ., 2016). In a more recent study among only MDR-TB patients, the prevalence of depression was estimated as 22.2%.…”

“…The sample size was calculated using the following formula (Naing et al ., 2006):where N = sample size, Z 2 = Z statistic for a level of confidence (95%), P = prevalence (18%) (Devkota et al ., 2016), and d = precision (5%).…”

“…where N = sample size, Z 2 = Z statistic for a level of confidence (95%), P = prevalence (18%) (Devkota et al, 2016), and d = precision (5%). Based on the above mentioned values, the sample size (N ) was calculated as follows:…”

“…Two studies in Nepal have assessed the prevalence of depression among patients with drug-susceptible TB and MDR-TB, respectively. At an urban directly observed treatment short-course (DOTS) center in Kathmandu, of the 150 TB patients included in the sample, 18% had depression (Devkota et al ., 2016). The frequency of mild depression was 16 (11%), for moderate depression was 6 (4%), for severe depression was 3 (2%) and that for very severe depression was 2 (1%).…”

Factors Associated with Treatment Adherence among Tuberculosis Patients in Gandaki Province of Nepal

“…According to the research conducted in Kathmandu, Nepal; National tuberculosis program Nepal 2011 report and Ethiopia which shows that majority of respondents were male and suffered from Extra Pulmonary Tuberculosis whereas the present research also shows that majority of respondents were also male but the majority of respondents were suffered from pulmonary tuberculosis. It might be due to the correctional health facilities and present at a time of data collection [26,27] .…”