Health risk assessment of various metal(loid)s via multiple exposure pathways on children living near a typical lead-acid battery plant, China

Cao, Suzhen; Duan, Xiaoli; Zhao, Xueyan; Wang, Beibei; Ma, Jin; Fan, Delong; Sun, Chaofen; He, Bin; Wei, Fusheng; Jiang, Guibin

doi:10.1016/j.envpol.2015.02.010

Cited by 187 publications

(73 citation statements)

References 48 publications

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“…In this study, carcinogenic risk induced by Cr, As, and Cd exceeded the maximal acceptable risk level, indicating that carcinogenic risk from these three metals in drinking water is higher than the non-carcinogenic risk from seven metals from drinking water in both areas. This result is similar to most other related studies (Zhang et al 2014a, b;Cao et al 2015), but different from the study conducted in Shenzhen, China, which concluded that the non-cancer risk was higher than the cancer risk from heavy metals in drinking water (Lu et al 2015).…”

Section: Non-carcinogenic Risk Assessmentsupporting

confidence: 53%

Occurrence and health risk assessment of selected metals in drinking water from two typical remote areas in China

Geng

Liu

et al. 2016

Environ Sci Pollut Res

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The potential contaminations of 16 trace elements (Cr, Mn, Ni, Cu, Zn, As, Cd, Sb, Ba, Pb, Co, Be, V, Ti, Tl, Al) in drinking water collected in two remote areas in China were analyzed. The average levels of the trace elements were lower than the allowable concentrations set by national agencies, except for several elements (As, Sb, Mn, and Be) in individual samples. A health risk assessment model was conducted and carcinogenic and non-carcinogenic risks were evaluated separately. The results indicated that the total carcinogenic risks were higher than the maximum allowed risk level set by most organizations (1 × 10(-6)). Residents in both study areas were at risk of carcinogenic effects from exposure to Cr, which accounted for 80-90 % of the total carcinogenic risks. The non-carcinogenic risks (Cu, Zn, Ni) were lower than the maximum allowance levels. Among the four population groups, infants incurred the highest health risks and required special attention. Correlation analysis revealed significant positive associations among most trace elements, indicating the likelihood of a common source. The results of probabilistic health risk assessment of Cr based on Monte-Carlo simulation revealed that the uncertainty of system parameters does not affect the decision making of pollution prevention and control. Sensitivity analysis revealed that ingestion rate of water and concentration of Cr showed relatively high sensitivity to the health risks.

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Section: Non-carcinogenic Risk Assessmentsupporting

confidence: 53%

Occurrence and health risk assessment of selected metals in drinking water from two typical remote areas in China

Geng

Liu

et al. 2016

Environ Sci Pollut Res

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“…Our results confirmed that exposure to toxic metals from soils and sediments would cause high potential ecological risks and health risks in this area, although the results would inevitably be affected by the inherent uncertainty in risk assessment (USEPA, 1989;Cao et al, 2015). In this study, bioavailability of the metals in soils and sediments was not considered, which might result in an overestimation of the potential risks.…”

Section: Risk Characteristics Of Contaminationsupporting

confidence: 57%

Contamination and risk of heavy metals in soils and sediments from a typical plastic waste recycling area in North China

Tang

Zhang

Huang

et al. 2015

Ecotoxicology and Environmental Safety

140

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a b s t r a c tPlastic wastes are increasingly being recycled in many countries. However, available information on the metals released into the environment during recycling processes is rare. In this study, the contamination features and risks of eight heavy metals in soils and sediments were investigated in Wen'an, a typical plastic recycling area in North China. The surface soils and sediments have suffered from moderate to high metal pollution and in particular, high Cd and Hg pollution. The mean concentrations of Cd and Hg were 0.355 and 0.408 mg kg À 1 , respectively, in the soils and 1.53 and 2.10 mg kg À 1 , respectively, in the sediments. The findings suggested that there is considerable to high potential ecological risks in more than half of the soils and high potential ecological risk in almost all sediments. Although the health risk levels from exposure to soil metals were acceptable for adults, the non-carcinogenic risks to local children exceeded the acceptable level. Source assessment indicated that heavy metals in soils and sediments were mainly derived from inputs from poorly controlled plastic waste recycling operations in this area. The results suggested that the risks associated with heavy metal pollution from plastic waste recycling should be of great concern.

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“…If HQ 1, adverse health effects would be unlikely to be experienced, whereas potential non-carcinogenic effects would occur when HQ > 1 (Cao et al, 2015).…”

Section: Principal Component Analysis (Pca)mentioning

confidence: 99%

“…In the present study, we adapted the health risk assessment models of the U.S. EPA to evaluate the health risks of the heavy metals. The average daily doses through ingestion (ADD ing ) (mg/kg/day), inhalation (ADD inh ) (mg/kg/day), and dermal contact (ADD dermal ) (mg/kg/day) were calculated as follows (Cao et al, 2015):…”

Section: Principal Component Analysis (Pca)mentioning

confidence: 99%

Heavy metals bound to fine particulate matter from northern China induce season-dependent health risks: A study based on myocardial toxicity

Zhang

et al. 2016

Environmental Pollution

130

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Substantial epidemiological evidence has consistently reported that fine particulate matter (PM2.5) is associated with an increased risk of cardiovascular outcomes. PM2.5 is a complex mixture of extremely small particles and liquid droplets composed of multiple components, and there has been high interest in identifying the specific health-relevant physical and/or chemical toxic constituents of PM2.5. In the present study, we analyzed 8 heavy metals (Cr, Ni, Cu, Cd, Pb, Zn, Mn and Co) in the PM2.5 collected during four different seasons in Taiyuan, a typical coal-burning city in northern China. Our results indicated that total concentrations of the 8 heavy metals differed among the seasons. Zn and Pb, which are primarily derived from the anthropogenic source, coal burning, were the dominant elements, and high concentrations of these two elements were observed during the spring and winter. To clarify whether these heavy metals in the locally collected PM2.5 were associated with health effects, we conducted health risk assessments using validated methods. Interestingly, Pb was responsible for greater potential health risks to children. Because cardiovascular disease (CVD) is a main contributor to the mortality associated with PM2.5 exposure, we performed experimental assays to evaluate the myocardial toxicity. Our in vitro experiments showed that the heavy metal-containing PM2.5 induced season-dependent apoptosis in rat H9C2 cells through a reactive oxygen species (ROS)-mediated inflammatory response. Our findings suggested that heavy metals bound to PM2.5 produced by coal burning play an important role in myocardial toxicity and contribute to season-dependent health risks.

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Health risk assessment of various metal(loid)s via multiple exposure pathways on children living near a typical lead-acid battery plant, China

Cited by 187 publications

References 48 publications

Occurrence and health risk assessment of selected metals in drinking water from two typical remote areas in China

Occurrence and health risk assessment of selected metals in drinking water from two typical remote areas in China

Contamination and risk of heavy metals in soils and sediments from a typical plastic waste recycling area in North China

Heavy metals bound to fine particulate matter from northern China induce season-dependent health risks: A study based on myocardial toxicity

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