Plant-derived silver nanoparticles (AgNPs) have been demonstrated to possess effective antibacterial effects and have been vastly used in medicine. 6 Green synthesis method has been studied because of their renewability, 7 simplicity and eco-friendliness, 8 inherent antimicrobial activities, and preservative properties of the obtained AgNPs. 9 Plant components including leaves, fruits, roots, stems and leaves have been widely utilized to synthesize different NPs which are currently being used in different applications, 10 including fish preservation. The presence of a wide array of phytochemicals in their extracts may function as natural stabilizing and/or reducing agents for AgNPs production. 11 It is generally accepted that plant-derived nanoparticles (NPs) are also less likely to have harmful side effects in humans when compared to chemically synthesized NPs. 5 This is because the reductants, which are phytochemicals also possess beneficial biological effects, making them biocompatible. Thus, plants provide a far better alternative for nanоparticles synthesis as they are free from tоxic chemicals that are associated with the chemical method of synthesis. 12 Furthermore, the inherent biomolecules in plants serve as natural capping agents, which prevent oxidation of the synthesized NPs. 13 Launaea taraxacifolia of the family Asteraceae used for this study is a green leafy vegetable (Figure 1) locally cultivated and widely consumed in Nigeria, Senegal, Ghana, Dahomey, and Sierra Leone. 14 It is also known as African lettuce or wild lettuce. In Nigeria, Hausas call it 'Namijindayii, Nomenbarewa, and NonanBarya' while Yorubas call it 'EfoYanrin and Odundun odo. It is a wild plant that grows individually or in clusters on fields, rocky soil, fallows, and abandoned areas. The economic values of this plant were highlighted by Adebisi & Ladipo, 14 for its utility as food, fodders for animals, lactogen in cattle, and induction of multiple births in livestock. In Nigeria, it is employed as a cure for several complaints such as eye diseases (conjunctivitis), yaws, and measles. 14 The leaf extract mixed with the breast milk of a nursing