Background: Medication adherence is a growing concern to healthcare systems as non-adherence to pharmacotherapy has been associated with adverse outcomes and higher costs of care. Objective: To assess the determinants of Patient’s adherence to Hypertensive medication and to evaluate the levels of adherence based on Health belief Model.Methods: A cross-sectional study conducted in the OPDs of Rural Health Centres of a tertiary care hospital over a period of 4 months(April’16 –July’16) using a semi-structured and validated questionnaire which contain information on demographic characteristics, medication and health related facility and Health Belief Model. All hypertensives taking medication for more than 6 months were included in this study. Medication Adherence was assessed using the Morisky Medication Adherence Scale-8(MMAS-8).Statistical Analysis: Data was analysed using SPSS and P value <0.05 was considered statistically significant.Results: Out of 300 patients, 114 were males and 186 were females. The level of Adherence was 23% in our study subjects. Gender (0.05), Religion (0.02), Marital status (0.035), Socioeconomic status (p=0.000) and Frequency of medication (p=0.000) had association with adherence. Based on health belief model, perceived severity (p=0.000), perceived susceptibility (p=0.000), perceived benefit (p=0.000), perceived barrier (p=0.000), Cue to action (p=0.025) and self-efficacy (p=0.00) had association with adherence.Conclusions: Patients Knowledge, understanding and perception can improve the adherence to medication. The results of our study can be used for better treatment of Hypertension.