Health Stimulating Properties of Resveratrol

Kopeć, Aneta; Piątkowska, Ewa; Leszczyńska, Teresa; Bieżanowska-Kopeć, Renata

doi:10.15193/zntj/2011/78/005-015

Cited by 4 publications

(6 citation statements)

References 33 publications

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“…Resveratrol is a major secondary metabolite in peanuts. It is associated with anticancer, anti-inflammatory, and neuroprotective effects; protective effects on the cardiovascular system; and prevention against degenerative diseases [65]. It is also considered an effective scavenger of reactive oxygen species (ROS) and reactive nitrogen species (RNS) produced during metabolic processes [66], which play a major role in maintaining the oxidation-reduction balance in cells expressing antioxidant enzymes, such as catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase [67,68].…”

Section: Discussionmentioning

confidence: 99%

The Influence of Light Wavelength on Resveratrol Content and Antioxidant Capacity in Arachis hypogaeas L.

Chung

Lee²,

Hwang

et al. 2021

Agronomy

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The quality and intensity of light can have a huge influence on plant growth and bioactive compound production. Compared to conventional lighting, very little is known about the influence of light emitting diodes (LED) irradiation on the antioxidant and antimicrobial properties and resveratrol content of peanut sprouts. This study was aimed at understanding the effects of LED light on the growth and antioxidant capacity of peanut sprouts. The resveratrol concentration was determined by liquid chromatography–tandem mass spectrometry. Peanut sprouts grown under blue LED light exhibited a higher total resveratrol content grown than those under fluorescent light and other LED light sources. The highest total phenolic content was recorded in the case of blue LED. The 1,1-diphenyl-2-picrylhydrazyl and 2,2-azino-bis 3-ethylbenzothiazoline-6-sulfonic acid radical scavenging values of blue LED‒treated and micro-electrodeless light-treated sprouts were significantly (p < 0.05) higher than that of sprouts grown under lights with other wavelengths. A Pearson correlation analysis revealed a strong association of the resveratrol, total phenolic, and flavonoid contents of peanut sprouts with 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2-azino-bis 3-ethylbenzothiazoline-6-sulfonic acid (ABTS), indicating its contribution to antioxidant activities. The anti-tyrosinase activity increased with an increase in the concentration of the tested sample. Blue LED-irradiated peanut extracts at a selected concentration range showed moderate cytotoxicity. Furthermore, the antimicrobial activity of peanut sprouts grown under blue LED was effective against Escherichia coli, Klebsiella pneumonia, and Vibrio litoralis. The present study revealed that the application of LEDs during the peanut sprouts growth improves the antioxidant activity, resveratrol concentration, and metabolite accumulation.

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Section: Discussionmentioning

confidence: 99%

The Influence of Light Wavelength on Resveratrol Content and Antioxidant Capacity in Arachis hypogaeas L.

Chung

Lee²,

Hwang

et al. 2021

Agronomy

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“…negative side effects such as hyperplastic changes of kidneys and gallbladder, diarrhea, vomiting, leukocytosis, and more. A lower dose of 0.3 g/kg b.w./day for 4 weeks did not show any side effects[68,69] and may be added to multi-domain interventions. Similarly, probiotic bacteria should be taken into account when thinking about such studies, as these contain anti-inflammatory effects on the digestive system with various benefits.…”

mentioning

confidence: 85%

Influence of a 12-Month Structured Exercise Program on the Micronutrient-Cognitive Fitness-Physical Association Profiles in Mild Cognitive Impairment

Weigert

Stuckenschneider

Pickert

et al. 2022

ADR

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Background: Preventive lifestyle strategies have shown promise to slow down or prevent age-related cognitive decline. However, evidence on the reciprocal longitudinal relationships between nutrition biomarkers and cognitive and physical performance is lacking. Studying nutritional, cognitive, and physical profiles over time may help to overcome this knowledge gap. Objective: To investigate the relationship of plasma levels of the robust nutritional- and antioxidant defense-related biomarkers carotenoids and tocopherols with both indicators of cognitive and physical performance in persons with mild cognitive impairment (MCI) participating in a structured exercise program. Methods: Data from 40 participants with MCI of the NeuroExercise study were analyzed. Participants had undergone a blood withdrawal for the analysis of plasma concentrations of six carotenoids, two tocopherols and retinol prior to and after one-year of structured exercise. All participants had undergone a broad spectrum of cognitive and physical performance tests. Results: Significant associations between lipophilic micronutrients and cognitive/physical measures were observed that were previously found to play a role in cognitive and physical frailty. In particular, lutein, zeaxanthin, and lycopene are confirmed as robust, reliable, and stable indicators of nutritional defense. Importantly, these micronutrients were associated with cognitive measures prior to the physical training program and to a more prominent extent with indicators of motoric function after the physical exercise program. Conclusion: Specific profiles of lipophilic micronutrients are associated to cognitive performance measures and, especially after a structured exercise program, to indicators of physical performance.

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“…Największą zawartość resweratrolu mają czerwone winogrona odmiany Pinot noir. Związek ten występuje również w owocach jagodowych (żurawina, borówka amerykańska, borówka czernica, borówka brusznica, morwa, maliny, truskawki, czarna porzeczka), jabłkach i owocach chlebowca [13].…”

Section: Kumarynyunclassified

“…Hamowanie fazy inicjacji wynika z jego zdolności do detoksykacji kancerogenów w komórkach raka wątroby na zasadzie indukcji reduktazy chinonowej (QR-2), zdolności do usuwania reaktywnych form tlenu, aktywności przeciwmutagennej. Resweratrol działa również poprzez zmniejszenie aktywności i ekspresji izoenzymów cytochromu P450: CYP1A1, CYP1A2 i CYP2B1 [13]. Indukuje również ekspresję genu p53, posiadającego zdolność do hamowania procesów nowotworowych.…”

Section: Kumarynyunclassified

“…W innym badaniu przez 29 dni podawano osobom zdrowym resweratrol w dawkach od 500 mg do 5 g. We krwi badanych stwierdzono niezależne od dawki zahamowanie wytwarzania czynników wzrostu IGFPB-3 oraz IGF-1, które związane są z rozwojem procesu nowotworowego [27]. Jako fitoestrogen reguluje również ekspresję wielu genów związanych z rozwojem raka piersi [13].…”

Section: Kumarynyunclassified

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Wybrane Substancje Bioaktywne Pochodzenia Roślinnego I Ich Rola W Zapobieganiu Nowotworom

Goderska¹,

Nikrandt²

2022

zntj

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Background. Cancer poses a major public health challenge. Cancer treatment is expensive, burdened with many side effects, and in the case of some types of cancer, ineffective. This is related to the high degree of complexity of metabolic disorders accompanying the growth of neoplastic tissue. Therefore, special attention is paid to primary prevention, the aim of which is to reduce the risk of disease. Primary prevention activities focus on reducing exposure to modifiable risk factors, which include e.g. smoking, alcohol consumption, low physical activity and poor diet. Results and conclusion. The paper presents literature reports on the protective effect of bioactive compounds of plant origin against the development of cancer. Individual groups of compounds such as fibre, stilbenes, carotenoids, glucosinolates, betalains, phytitians, flavonoids, isoflavones and anthocyanins were characterized. The anti-carcinogenic properties of bioactive ingredients are discussed, taking into account the molecular mechanisms underlying their action. Particular attention was paid to the sources of compounds with anticancer activity present in food and the way these substances act on the processes of growth and migration of cancer cells. In addition, the results of experiments using in vitro and in vivo models as well as case-control trials with human participants are presented.

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Health Stimulating Properties of Resveratrol

Cited by 4 publications

References 33 publications

The Influence of Light Wavelength on Resveratrol Content and Antioxidant Capacity in Arachis hypogaeas L.

The Influence of Light Wavelength on Resveratrol Content and Antioxidant Capacity in Arachis hypogaeas L.

Influence of a 12-Month Structured Exercise Program on the Micronutrient-Cognitive Fitness-Physical Association Profiles in Mild Cognitive Impairment

Wybrane Substancje Bioaktywne Pochodzenia Roślinnego I Ich Rola W Zapobieganiu Nowotworom

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