Health Technology Assessment In Singapore: Shining A Light In The Darkness

Viswambaram, A; Brooks-Rooney, C.

doi:10.1016/j.jval.2017.08.1593

Cited by 2 publications

(4 citation statements)

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“…A cost-utility analysis was conducted to evaluate the cost-effectiveness of VACOM compared to IPC plus manual ankle movement. A ceiling threshold of S$75,000 was considered for the Singapore setting (49).…”

Section: Methodsmentioning

confidence: 99%

Using early health economic modeling to inform medical innovation development: a soft robotic sock in poststroke patients in Singapore

Wang

Low

et al. 2023

Int J Technol Assess Health Care

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Objectives Based on a real-world collaboration with innovators in applying early health economic modeling, we aimed to offer practical steps that health technology assessment (HTA) researchers and innovators can follow and promote the usage of early HTA among research and development (R&D) communities. Methods The HTA researcher was approached by the innovator to carry out an early HTA ahead of the first clinical trial of the technology, a soft robotic sock for poststroke patients. Early health economic modeling was selected to understand the potential value of the technology and to help uncover the information gap. Threshold analysis was used to identify the target product profiles. Value-of-information analysis was conducted to understand the uncertainties and the need for further research. Results Based on the expected price and clinical effectiveness by the innovator, the new technology was found to be cost-saving compared to the current practice. Risk reduction in deep vein thrombosis and ankle contracture, the incidence rate of ankle contracture, the compliance rate of the new technology, and utility scores were found to have high impacts on the value-for-money of the new technology. The value of information was low if the new technology can achieve the expected clinical effectiveness. A list of parameters was recommended for data collection in the impending clinical trial. Conclusions This work, based on a real-world collaboration, has illustrated that early health economic modeling can inform medical innovation development. We provided practical steps in order to achieve more efficient R&D investment in medical innovation moving forward.

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Section: Methodsmentioning

confidence: 99%

Using early health economic modeling to inform medical innovation development: a soft robotic sock in poststroke patients in Singapore

Wang

Low

et al. 2023

Int J Technol Assess Health Care

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“…The importance of experts' opinion based on clinical experience, in the choice of conditions to be screened for is also present in other Southeast countries, as Cambodia and Laos [54][55]. In other countries, such as Singapore [56][57], Thailand [58] and the Philippine [59], the decision to include a particular condition tend to be based on strong evidence demonstrating the effectiveness of screening and the potential benefits to affected individuals and families Changes brought by the technological diagnostic development in the field of neonatal screening, a new understanding of screenable conditions, and new possibilities of treatment, have fueled the expansion of NBS programs around the world [60][61]. However, Vietnam as many other LMICs is not taking part in this trend, but the government has set a specific target according to which, by 2030, 90% of newborns should be screened for at least 5 of the most common congenital diseases in the country: GPD deficiency; congenital hypothyroidism; congenital adrenal hyperplasia, galactose metabolism disorder, and phenylketonuria.…”

Section: Ee For Nbs Programs In Lmicsmentioning

confidence: 99%

“…It can therefore look for foreign support in its mandate to evaluate interventions. One notes, the HSPI has a Department of Health Economics that, among its responsibilities, has to promote the production of relevant economic data on interventions that could be offered to the population [53][54][55][56][57][58][59][60][61][62].…”

Section: Ee For Nbs Programs In Lmicsmentioning

confidence: 99%

“…Unfortunately, there is no real substitute to the HSPI in the country. As a consequence, as in many other LMICs, Vietnam has few explicit formal frameworks and guidelines for pricing and reimbursement processes [53][54][55][56][57][58][59][60][61][62][63] that are needed to make EE studies. Again, decisions are mainly taken based on experts' opinion and regulatory requirements [53].…”

Section: Ee For Nbs Programs In Lmicsmentioning

confidence: 99%

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Expected Benefits and Challenges of Using Economic Evaluations to Make Decisions About the Content of Newborn Screening Programs in Vietnam: A Scoping Review of the Literature

Giguère

Reinharz

2023

J. inborn errors metab. screen.

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Screening newborns for genetic and other diseases is one of the most effective ways to improve health and reduce disease in a population. In developed countries, newborn screening has been a cornerstone of public health for decades. In many developing countries, however, newborn screening is still in its infancy. Many countries still lack screening programs. When a program is available, it generally lacks well-defined criteria on which decision-makers can justify the choice of diseases screened for and the methods used. One of the reasons put forward to understand this observation is the fact that little consideration is given by decision-makers to economic evaluations as a pillar of decision-making, as is the case in industrialized countries. This article provides a brief description of the challenges of using economic evaluation of newborn screening in developing countries. This will be illustrated by the example of the national newborn screening program in Vietnam.

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Health Technology Assessment In Singapore: Shining A Light In The Darkness

Cited by 2 publications

References 0 publications

Using early health economic modeling to inform medical innovation development: a soft robotic sock in poststroke patients in Singapore

Using early health economic modeling to inform medical innovation development: a soft robotic sock in poststroke patients in Singapore

Expected Benefits and Challenges of Using Economic Evaluations to Make Decisions About the Content of Newborn Screening Programs in Vietnam: A Scoping Review of the Literature

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