Health utility scores of family caregivers for leukemia patients measured by EQ-5D-3L: a cross-sectional survey in China

Yu, Hongjuan; Zhang, Huan; Yang, Jian; Liu, George; Lu, Chengfang; Yang, Hongbin; Huang, Weidong; Zhou, Jin; Fu, Wang; Shi, Linmei; Yan, Yan; Liu, Guoxiang; Liu, Limin

doi:10.1186/s12885-018-4855-y

Cited by 20 publications

(22 citation statements)

References 38 publications

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“…Health is a complex concept, so there are many methods and indicators to measure the health status of residents. The European five-dimensional health scale (EQ-5D) is widely used by researchers due to its simplicity and high credibility [23][24][25]. Zhang divided the health of the elderly into three aspects: physical health, cognitive function, and self-evaluated health [26].…”

Section: Outcome Variablesmentioning

confidence: 99%

The Effects of China’s Targeted Poverty Alleviation Policy on the Health and Health Equity of Rural Poor Residents: Evidence from Shaanxi Province

2020

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Objective: China’s targeted poverty alleviation policy has a profound impact on the country’s rural economic and social development now. This study aimed to learn about the health status and health equity of rural poor residents under the implementation of the policy. It further explores the factors affecting the health status and health equity of rural poor residents in order to contribute to the improvement of the policy. Methods: The data of 1233 rural poor residents were collected from a questionnaire survey from 12 prefecture-level cities and areas of Shaanxi province in 2017, and the self-reported health was used to reflect the health status. A concentration index was applied to measure the inequity of the health status of rural poor residents. The decomposition method was employed to explore the source of health inequity. Results: The results showed that 44.56% of rural poor residents in Shaanxi province had a poor or very poor health status, which was affected by their economic level, gender, age, degree of education, and marital status. Additionally, participation in agricultural industry development, relocation, health poverty alleviation, and basic living standards were significantly correlated with health status. The concentration index of the health status of rural poor residents was 0.0327. The primary contributors to the health inequity in different regions varied, but the economic level and the degree of education were the most significant factors, and the targeted poverty alleviation policy had a significant impact on health equity. Conclusions: The results indicated that the health status of rural poor residents in Shaanxi province was generally poor, there was a pro-rich inequity in the health status, and the degree of education and economic level were the primary factors affecting the health status and health equity. The targeted poverty alleviation policy greatly impacted the health status and health equity of rural poor residents, and the difference in health status would lead to the inequity of benefits of the targeted poverty alleviation policy. In the future, the policy should focus on ensuring the sustainable development ability of rural residents with poor health status.

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Section: Outcome Variablesmentioning

confidence: 99%

The Effects of China’s Targeted Poverty Alleviation Policy on the Health and Health Equity of Rural Poor Residents: Evidence from Shaanxi Province

2020

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“…The initial screening retrieved 9426 citations, and following the data-extraction process, 12 primary studies (reported in 17 publications) were included in the HRQoL burden review (Figure 1). The 12 studies differed in terms of design, study populations, and the instruments used to measure HRQoL burden (Table 1) [14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] . The majority of studies were conducted in the United States (n ¼ 6) and Europe (n ¼ 3); study populations included both treated and untreated patients, as well as those with R/R disease.…”

Section: Hrqol Burden Of Cllmentioning

confidence: 99%

Health-related quality of life and economic burden of chronic lymphocytic leukemia in the era of novel targeted agents

Waweru

Kaur

Sharma

2020

Current Medical Research and Opinion

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Objective: To quantify the health-related quality of life (HRQoL) and economic burden of chronic lymphocytic leukemia (CLL). Methods: Studies were searched through Embase, MEDLINE, PubMed, and Cochrane Library, as well as conference abstracts (1 January 2000-2 June 2019). Results: Overall, 12 and 17 primary studies were included in the HRQoL and economic burden reviews, respectively. Patients with CLL reported impairment in various quality of life domains when compared with healthy controls, including fatigue, anxiety, physical functioning, social functioning, depression, sleep disturbance, and pain interference. Key factors associated with a negative impact on the HRQoL burden of CLL included female gender, increased disease severity, and the initiation of multiple lines of therapy. Economic burden was assessed for patients with CLL based on disease status and the treatment regimen received. The main cost drivers related to CLL were outpatient and hospitalization-related costs, primarily incurred as a result of chemo/chemoimmunotherapy, adverse events (AEs), and disease progression. Treatment with targeted agents, i.e. ibrutinib and venetoclax, was associated with lower medical costs than chemoimmunotherapy, although ibrutinib was associated with some increased AE costs related to cardiac toxicities. Cost studies of targeted agents were limited by short follow-up times that did not capture the full scope of treatment costs. Conclusions: CLL imposes a significant HRQoL and economic burden. Our systematic review shows that an unmet need persists in CLL for treatments that delay progression while minimizing AEs. Studies suggest targeted therapies may reduce the economic burden of CLL, but longer follow-up data are needed.

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“…The quality of life (QoL) was assessed by using the Chinese version EuroQol (EQ-5D-3L)(10), which has been previously validated (11)(12)(13). The questionnaire of EQ-5D-3L consists of two parts.…”

Section: Measures Of Quality Of Life and In Uencing Factorsmentioning

confidence: 99%

Quality of life during the epidemic of COVID-19 and its associated factors among enterprise workers in East China

Chen¹,

Lin

et al. 2020

Preprint

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Background: The impact of COVID-19 related quarantine on quality of life was expected and unclear for enterprise workers. We investigated the quality of life during the epidemic in enterprise workers just returned to work and assessed its potential influencing factors to get a better understanding of the impact of COVID-19 epidemic. Methods: This was a cross-sectional study among enterprise workers in Deqing and Taizhou, Zhejiang Province, China. Chinese version of EQ5D to assess life quality, and information about general characteristics and COVID-19 related information was collected by a structured questionnaire online distributed through the social application “Wechat”. Results: A total of 2435 participants were enrolled, 59.5% of which worked in Deqing. About 50% reported worries about the COVID-2019 epidemic and 40.1% of participants performed centralized or home quarantine during the epidemic. The mean EQ-5D score and VAS were 0.990 and 93.5. Multiple logistic regression suggested that physical activities (ORad=0.46) and keeping home ventilation (ORad=0.04) was related with life quality in Deqing, while for participants in Taizhou, wearing a mask when going out (ORad=0.35), keeping home ventilation (ORad=0.16), unmarried status (ORad=2.38) and experienced centralized or home quarantine (ORad=1.64) was related with quality of life.Conclusions: Enterprise workers in two areas with different risk of COVID-19 experienced different life quality during the epidemic of COVID-19. Physical activity, marital status, worry about epidemic of COVID-19, keeping home ventilation, wearing a mask and quarantine were related with quality of life.

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Health utility scores of family caregivers for leukemia patients measured by EQ-5D-3L: a cross-sectional survey in China

Cited by 20 publications

References 38 publications

The Effects of China’s Targeted Poverty Alleviation Policy on the Health and Health Equity of Rural Poor Residents: Evidence from Shaanxi Province

The Effects of China’s Targeted Poverty Alleviation Policy on the Health and Health Equity of Rural Poor Residents: Evidence from Shaanxi Province

Health-related quality of life and economic burden of chronic lymphocytic leukemia in the era of novel targeted agents

Quality of life during the epidemic of COVID-19 and its associated factors among enterprise workers in East China

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