Health Utility Values Associated with Surgical Site Infection: A Systematic Review

Gheorghe, Adrian; Moran, Grace M; Duffy, Helen; Roberts, Tracy; Pinkney, Thomas; Calvert, Melanie

doi:10.1016/j.jval.2015.08.004

Cited by 62 publications

(56 citation statements)

References 84 publications

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“…EQ-5D scores demonstrated that SSIs negatively impact on patient HRQoL, demonstrated by a statistically significant reduction in HRQoL scores (11%) at 30 days in patients who underwent laparotomy surgery, relative to patients who did not develop an SSI [9]. It is noteworthy that the results of this study were also included in a recent systematic review by Gheorghe et al, who reported that the SSI utility decrement in patients who developed an SSI after laparotomy surgery was 0.05 at 7 days and 0.12 at 30 days (Table V) [35].…”

Section: Quality Of Lifementioning

confidence: 56%

Impact of surgical site infection on healthcare costs and patient outcomes: a systematic review in six European countries

Badia

Casey

Petrosillo

et al. 2017

Journal of Hospital Infection

661

465

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Section: Quality Of Lifementioning

confidence: 56%

Impact of surgical site infection on healthcare costs and patient outcomes: a systematic review in six European countries

Badia

Casey

Petrosillo

et al. 2017

Journal of Hospital Infection

661

465

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“…Yet, they still represent a significant clinical and economic burden to the health care system [17][18][19][20][21]. In particular, wound infections are responsible for longer hospitalizations, increased costs for antibiotic therapy and topical wound care during the same admission and after discharge.…”

Section: The Economic and Clinical Burden Of Wound Infectionsmentioning

confidence: 99%

“…However, there are several observational studies and systematic reviews that analyzed the costs of robotic assisted prostatectomies or partial nephrectomies that can be used for our model [38,39]. Similarly, costs of treatment of surgical site infections [20], repair of incisional hernias [40], utility of patients undergoing incisional hernia repair [21] will be extracted from nontransplant scientific literature as we will assume that these values are applicable to our study population.…”

Section: Rationale For Cost-effectiveness and Cost-benefit Analysismentioning

confidence: 99%

Robotic Versus Open Renal Transplantation in Obese Patients: Protocol for a Cost-Benefit Markov Model Analysis (Preprint)

Molinari¹,

Puttarajappa²,

Wijkstrom³

et al. 2017

Preprint

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A Markov model will be developed to simulate a randomized controlled study to assess the costeffectiveness of robotic-assisted renal transplantation in comparison to open surgery in obese patients. Project SummaryThe number of patients affected by renal insufficiency and obesity is growing, especially in North America where obesity has reached epidemic proportions. Obesity is associated with several comorbidities that increase the risks of wound complications. Wound infections are one of the most common nosocomial complications in patients who undergo contaminated surgical procedures or who are immunosuppressed or diabetic. Often, obese patients who undergo renal transplantation have diabetes in addition to being immunosuppressed and develop some degree of wound complications (infections, seromas, dehiscence, hernias) in up to 50% of cases. Wound complications represent a significant clinical and economic burden to the health-care system. In particular, wound infections are responsible for longer hospitalizations and decreased functional capacity of renal transplant recipients who require extramural nursing for the management of their wound-vacuum devices and local debridement and packing of their incisions.

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“…The infection of an operated wound, especially in the case of arthroplasty or orthopedic implants, can have disastrous effects, the removal of the foreign material being necessary. Postoperative infections interrupt the normal healing process, increasing the risk of some associated pathologies or decompensation of the pre-existent ones, but also prolong the hospitalization time with significant additional costs for health systems [12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Utility of microcalorimetry in describing the growth curve of C. albicans at different temperatures – indentifying the optimal growth temperature

Popa

Șerban

et al. 2019

Romanian Journal of Orthopaedic Surgery and Traumatology

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In comparison with other medical specialties, Orthopedics and Traumatology are continuously impressively developing, intrinsically connected to technological evolution. More than in other fields, in Orthopedics and Traumatology, the technological progress becomes obvious also by the frequent use of implants or osteosynthesis materials. By performing a simple search in the specialty literature, an exponential growth of arthroplasty surgeries in correlation with the life span of the population and implying a need that presupposes the increase of the quality of life, also by maintaining or improving mobility at a satisfying level, can be observed. At the same time, due to the increase in the number of traffic and sports accidents, the use of artificial joints and implants for osteosynthesis will constantly rise. The prostheses and the osteosynthesis materials used for the treatment of degenerative, traumatic or even esthetic pathologies are made of materials with a good biocompatibility. Candida albicans is an optional anaerobic microorganism so the experiments performed with different volumes of environment were most likely influenced by the amount of oxygen, nutrient. In the described research, we demonstrated that, using microcalorimetry, it is possible to identify this fungus in half the time required for classical microbiological identification. In addition, as our team has shown, there is the possibility of real-time antifungigram by using microcalorimetry.

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Health Utility Values Associated with Surgical Site Infection: A Systematic Review

Cited by 62 publications

References 84 publications

Impact of surgical site infection on healthcare costs and patient outcomes: a systematic review in six European countries

Impact of surgical site infection on healthcare costs and patient outcomes: a systematic review in six European countries

Robotic Versus Open Renal Transplantation in Obese Patients: Protocol for a Cost-Benefit Markov Model Analysis (Preprint)

Utility of microcalorimetry in describing the growth curve of C. albicans at different temperatures – indentifying the optimal growth temperature

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