Epilepsy is a neurological condition affecting millions worldwide, especially in low- and middle-income countries. This condition is poorly understood, and various misconceptions surround it, leading to stigma toward people living with epilepsy (PLWE). In rural areas, cultural beliefs and practices significantly shape attitudes toward health and illness, exacerbating the stigma associated with epilepsy. This proposed book addresses the pervasive stigma experienced by individuals living with epilepsy in rural communities. Through a review of relevant literature and case studies, this chapter examines how stigma affects the lives of people with epilepsy in rural areas. The chapter also explores strategies for reducing stigma, including community-based education and awareness programmes and the role of healthcare providers in promoting understanding and acceptance of epilepsy. In general, this chapter aims to highlight the need for increased awareness and understanding of epilepsy and its impact on those living with the condition in rural communities. It is believed that by tackling the stigma associated with epilepsy and promoting inclusivity, the quality of life of people living with epilepsy may be improved.