Hearing impairment after childhood bacterial meningitis dependent on etiology in Luanda, Angola

Karppinen, Mariia; Pelkonen, Tuula; Roine, Irmeli; Cruzeiro, Manuel Leite; Peltola, Heikki; Pitkäranta, Anne

doi:10.1016/j.ijporl.2015.08.015

Cited by 13 publications

(7 citation statements)

References 29 publications

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“…pneumoniae was the most common cause of impaired hearing at >60dB threshold among infants and it caused deafness more often than Hib and N . meningitidis 16 . In our study, there was no difference in hearing between children with or without OM on day 7, or later at the follow‐ups of 1, 3 and 6 months.…”

Section: Discussioncontrasting

confidence: 51%

“…Karppinen et al results showed that S. pneumoniae was the most common cause of impaired hearing at >60dB threshold among infants and it caused deafness more often than Hib and N. meningitidis. 16 In our study, there was no difference in hearing between children with or without OM on day 7, or later at the follow-ups of 1, 3 and 6 months. However, any hearing impairment or full deafness a week after the BM diagnosis showed a higher risk for complicated or fatal clinical course.…”

Section: Discussioncontrasting

confidence: 51%

“…BM patients, S . pneumoniae is the most common agent causing hearing impairment in 21%–50% of the cases, 11,12,15,16 in Hib and meningococcal meningitis, hearing impairment is seen in 6%–16% and 5%–24%, respectively 11,12,17 …”

Section: Introductionmentioning

confidence: 99%

“…[9][10][11][12] The mechanisms behind hearing loss are thought to be the destruction of the inner ear's neural elements followed by labyrinthitis and ossification of the cochlear scalae. 13,14 BM patients, S. pneumoniae is the most common agent causing hearing impairment in 21%-50% of the cases, 11,12,15,16 in Hib and meningococcal meningitis, hearing impairment is seen in 6%-16% and 5%-24%, respectively. 11,12,17 Our aim was to investigate bacterial aetiology, hearing impairment and outcome in childhood BM with vs. without OM in the resource-poor settings of Angola.…”

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confidence: 99%

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Hearing impairment in Angolan children with acute bacterial meningitis with and without otitis media

et al. 2022

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Aim Bacterial meningitis (BM) is a common cause of hearing loss in childhood. Our aim was to investigate bacterial aetiology, hearing impairment and outcome in childhood BM with vs. without otitis media (OM) in Angola. Methods Hearing was tested by auditory brainstem response in 391 (76%) children with confirmed BM. The bacteria identified from the ear discharge were compared to those from cerebrospinal fluid (CSF). The hearing findings were compared among children with vs. without OM on days 1 and 7 of hospitalization, and at follow‐ups of 1, 3 and 6 month(s). Results No correlation was found in bacteriology between the ear discharge and CSF. On day 7 in hospital, hearing impairment (>40 dB) was common, regardless of whether concomitant OM or not (in 27% vs. 30%, respectively). Any hearing deficit on day 7 was associated with a higher risk of complicated or fatal clinical course (OR 2.76, CI95% 1.43–5.29, p = 0.002). Conclusion No significant difference prevailed in hearing thresholds between children with or without OM in hospital on day 7 or at later follow‐ups. Any hearing impairment during hospital stay associated with a higher risk for complicated clinical course or death.

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Section: Discussioncontrasting

confidence: 51%

Section: Discussioncontrasting

confidence: 51%

Section: Introductionmentioning

confidence: 99%

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confidence: 99%

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Hearing impairment in Angolan children with acute bacterial meningitis with and without otitis media

et al. 2022

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“…Hearing impairment is the most common disability found among survivors of meningitis in LMICs (Edmond et al, 2010). The greatest proportion of research literature comes from the African continent, which bears the highest global burden of meningitis and post-infectious hearing impairment (Cherukupally & Eavey, 2004;Forsyth et al, 2004;Karppinen et al, 2015;Khowaja et al, 2013;Molyneux et al, 2003). All of the WHO member states in the Pacific Islands currently include immunisation against Haemophilus influenzae Type B (HiB) in their immunisation schedules, however, coverage rates are still below target levels (WHO, 2018f).…”

Section: Meningitismentioning

confidence: 99%

Paediatric ear disease and hearing loss in the Solomon Islands

Kaspar¹

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According to the World Health Organisation (WHO), around 90% of the global burden of hearing loss is found in Low-and Middle-Income Countries (LMICs). It is estimated that 75% of childhood hearing loss in LMICs is preventable. Otitis media (OM) and infectious diseases that may be avoided through immunisations are the leading causes of preventable hearing loss in children. Given the wellknown adverse effects of hearing loss in childhood development, the WHO is leading global efforts to address the burden of hearing loss in children through public health measures. Newborn and Infant Hearing Screening (NIHS) and school-based hearing screening programmes are key strategies that should facilitate early identification and intervention for children with hearing disorders. There is very little in the audiology literature on childhood hearing loss in the Pacific Islands. Yet, this region is estimated to have among the highest global burden of OM and disabling hearing loss. The limited literature indicates that OM begins early in life, and may quickly progress to advanced/chronic stages of disease and potentially fatal complications. Ear, Nose and Throat (ENT) and audiology services are virtually non-existent throughout the Pacific Islands, and public health measures such as community ear/hearing screening programmes may be a feasible option until more sophisticated ENT/audiology services become available. The Solomon Islands are a Pacific Island nation that is currently developing the outreach service of the ENT Clinic at the National Referral Hospital in the capital city, Honiara. The present study was developed to assess community engagement and readiness for ear/hearing screening programmes for children, as well as to assess the prevalence of OM and hearing loss among children in Honiara. Should the results of the study indicate that OM and hearing loss are a significant public health issue among children, and that caregivers are supportive of ear/hearing services, the recommendation for routine community-based ear/hearing screening programmes in Honiara will be justified. Parental knowledge and attitudes to childhood hearing loss and hearing services was assessed through semi-structured interviews with 150 parents attending community clinics in Honiara. The highest level of parental knowledge found regarding causes of hearing loss was for OM (94%). Knowledge of routine childhood immunisations (84%) and breast-feeding (76%) as public health measures to reduce/prevent OM were also high. The knowledge of fathers was generally the same or better than that of mothers. Approximately half of participants (56%) agreed that curses may cause childhood hearing loss. There was high parental support for infant hearing screening programmes (96%) and v Publications included in this thesis

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